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Homo sapiens (human) IRS-mediated signalling (provided by Reactome)

Browse by Letter Index, Genomic Locus

296 gene

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.


Gene Symbol Full Name
DUSP8 dual specificity phosphatase 8
EGF epidermal growth factor
TSC1 TSC complex subunit 1
PSMA4 proteasome subunit alpha 4
DUSP2 dual specificity phosphatase 2
LAMTOR4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
PSMB2 proteasome subunit beta 2
PPP2CB protein phosphatase 2 catalytic subunit beta
SRC SRC proto-oncogene, non-receptor tyrosine kinase
RASA2 RAS p21 protein activator 2
RAPGEF2 Rap guanine nucleotide exchange factor 2
SPTBN2 spectrin beta, non-erythrocytic 2
PSME4 proteasome activator subunit 4
KIT KIT proto-oncogene receptor tyrosine kinase
FGF20 fibroblast growth factor 20
PSMD7 proteasome 26S subunit, non-ATPase 7
LOC101930123 eukaryotic elongation factor 2 kinase
FGFR4 fibroblast growth factor receptor 4
FGA fibrinogen alpha chain
ARAF A-Raf proto-oncogene, serine/threonine kinase
FGF23 fibroblast growth factor 23
RPS6 ribosomal protein S6
ARRB1 arrestin beta 1
RASGRP4 RAS guanyl releasing protein 4
KBTBD7 kelch repeat and BTB domain containing 7
RASAL3 RAS protein activator like 3
DUSP1 dual specificity phosphatase 1
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
MTOR mechanistic target of rapamycin kinase
GRIN2C glutamate ionotropic receptor NMDA type subunit 2C
NF1 neurofibromin 1
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
PSME1 proteasome activator subunit 1
FGF22 fibroblast growth factor 22
DUSP9 dual specificity phosphatase 9
LOC102724229 uncharacterized LOC102724229
IL5 interleukin 5
PSMD8 proteasome 26S subunit, non-ATPase 8
TEK TEK receptor tyrosine kinase
PDE3B phosphodiesterase 3B
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
STK11 serine/threonine kinase 11
SPRED2 sprouty related EVH1 domain containing 2
CALM2 calmodulin 2
PDGFRB platelet derived growth factor receptor beta
RASA3 RAS p21 protein activator 3
PEA15 proliferation and apoptosis adaptor protein 15
PIK3R1 phosphoinositide-3-kinase regulatory subunit 1
FGF5 fibroblast growth factor 5
FGF1 fibroblast growth factor 1
CALM3 calmodulin 3
FRS3 fibroblast growth factor receptor substrate 3
RASGRF1 Ras protein specific guanine nucleotide releasing factor 1
EEF2K eukaryotic elongation factor 2 kinase
VWF von Willebrand factor
MARK3 microtubule affinity regulating kinase 3
RBX1 ring-box 1
KSR1 kinase suppressor of ras 1
MLST8 MTOR associated protein, LST8 homolog
IL3 interleukin 3
PRKAG3 protein kinase AMP-activated non-catalytic subunit gamma 3
IL5RA interleukin 5 receptor subunit alpha
AKT2 AKT serine/threonine kinase 2
SPTA1 spectrin alpha, erythrocytic 1
FGF9 fibroblast growth factor 9
GFRA1 GDNF family receptor alpha 1
PSMF1 proteasome inhibitor subunit 1
PSMC6 proteasome 26S subunit, ATPase 6
PSMC4 proteasome 26S subunit, ATPase 4
GFRA4 GDNF family receptor alpha 4
CSK C-terminal Src kinase
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
HRAS HRas proto-oncogene, GTPase
GFRA2 GDNF family receptor alpha 2
PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A
PSMD12 proteasome 26S subunit, non-ATPase 12
PTK2 protein tyrosine kinase 2
RET ret proto-oncogene
RANBP9 RAN binding protein 9
FGF4 fibroblast growth factor 4
KRAS KRAS proto-oncogene, GTPase
CAMK2G calcium/calmodulin dependent protein kinase II gamma
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
FGF3 fibroblast growth factor 3
PSMB3 proteasome subunit beta 3
MIR5004 microRNA 5004
IQGAP1 IQ motif containing GTPase activating protein 1
PSME3 proteasome activator subunit 3
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
PSMD10 proteasome 26S subunit, non-ATPase 10
PSMD2 proteasome 26S subunit, non-ATPase 2
PSMC3 proteasome 26S subunit, ATPase 3
PSMD6 proteasome 26S subunit, non-ATPase 6
RASAL2 RAS protein activator like 2
UBC ubiquitin C
MAP2K1 mitogen-activated protein kinase kinase 1
DAB2IP DAB2 interacting protein
GRIN1 glutamate ionotropic receptor NMDA type subunit 1
PSMA5 proteasome subunit alpha 5
RAP1A RAP1A, member of RAS oncogene family
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