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Homo sapiens (human) IRS-mediated signalling (provided by Reactome)

296 gene

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.


Gene Symbol Full Name
GFRA3 GDNF family receptor alpha 3
FGF2 fibroblast growth factor 2
PPP2R5C protein phosphatase 2 regulatory subunit B'gamma
PSMC5 proteasome 26S subunit, ATPase 5
MET MET proto-oncogene, receptor tyrosine kinase
PPP2R5B protein phosphatase 2 regulatory subunit B'beta
MAP3K11 mitogen-activated protein kinase kinase kinase 11
PDGFA platelet derived growth factor subunit A
THEM4 thioesterase superfamily member 4
ARTN artemin
EIF4G1 eukaryotic translation initiation factor 4 gamma 1
IL2RA interleukin 2 receptor subunit alpha
EIF4B eukaryotic translation initiation factor 4B
PSMB8 proteasome subunit beta 8
CSF2 colony stimulating factor 2
ACTN2 actinin alpha 2
MAPK1 mitogen-activated protein kinase 1
PSMD11 proteasome 26S subunit, non-ATPase 11
SHC2 SHC adaptor protein 2
PSMA2 proteasome subunit alpha 2
PSMB1 proteasome subunit beta 1
RPTOR regulatory associated protein of MTOR complex 1
GRIN2D glutamate ionotropic receptor NMDA type subunit 2D
GRIN2A glutamate ionotropic receptor NMDA type subunit 2A
PSMB10 proteasome subunit beta 10
PPP2CA protein phosphatase 2 catalytic subunit alpha
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
PTPRA protein tyrosine phosphatase, receptor type A
IL17RD interleukin 17 receptor D
KL klotho
ITGA2B integrin subunit alpha 2b
PSMA8 proteasome subunit alpha 8
MIR7855 microRNA 7855
CALM1 calmodulin 1
CUL3 cullin 3
DLG4 discs large MAGUK scaffold protein 4
KITLG KIT ligand
PHB prohibitin
JAK1 Janus kinase 1
PRKAB2 protein kinase AMP-activated non-catalytic subunit beta 2
RRAGC Ras related GTP binding C
PEBP1 phosphatidylethanolamine binding protein 1
NRTN neurturin
CSF2RA colony stimulating factor 2 receptor alpha subunit
PSMD1 proteasome 26S subunit, non-ATPase 1
RASGRF2 Ras protein specific guanine nucleotide releasing factor 2
FGF19 fibroblast growth factor 19
IL2RB interleukin 2 receptor subunit beta
PRKAG1 protein kinase AMP-activated non-catalytic subunit gamma 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
TLR9 toll like receptor 9
RPS27A ribosomal protein S27a
RAP1B RAP1B, member of RAS oncogene family
IL3RA interleukin 3 receptor subunit alpha
AKT1 AKT serine/threonine kinase 1
PSME2 proteasome activator subunit 2
NRG2 neuregulin 2
BTC betacellulin
TRIB3 tribbles pseudokinase 3
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
CAMK2D calcium/calmodulin dependent protein kinase II delta
FGF6 fibroblast growth factor 6
EIF4E eukaryotic translation initiation factor 4E
ERBB2 erb-b2 receptor tyrosine kinase 2
FRS2 fibroblast growth factor receptor substrate 2
DUSP10 dual specificity phosphatase 10
DUSP7 dual specificity phosphatase 7
CNKSR2 connector enhancer of kinase suppressor of Ras 2
AKT1S1 AKT1 substrate 1
NEFL neurofilament light
IRS1 insulin receptor substrate 1
ERBB4 erb-b2 receptor tyrosine kinase 4
GAB1 GRB2 associated binding protein 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
GDNF glial cell derived neurotrophic factor
ITGB3 integrin subunit beta 3
PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2
ERBB3 erb-b2 receptor tyrosine kinase 3
SHC1 SHC adaptor protein 1
RASAL1 RAS protein activator like 1
SEM1 SEM1, 26S proteasome complex subunit
APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein
SYNGAP1 synaptic Ras GTPase activating protein 1
RHEB Ras homolog, mTORC1 binding
PSMD9 proteasome 26S subunit, non-ATPase 9
FYN FYN proto-oncogene, Src family tyrosine kinase
FGF10 fibroblast growth factor 10
CSF2RB colony stimulating factor 2 receptor beta common subunit
PSMD4 proteasome 26S subunit, non-ATPase 4
MIR6852 microRNA 6852
PDPK1 3-phosphoinositide dependent protein kinase 1
PSMD13 proteasome 26S subunit, non-ATPase 13
PSMC1 proteasome 26S subunit, ATPase 1
NCAM1 neural cell adhesion molecule 1
PDGFB platelet derived growth factor subunit B
KSR2 kinase suppressor of ras 2
PSMB6 proteasome subunit beta 6
PSMC2 proteasome 26S subunit, ATPase 2
PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3
FGF18 fibroblast growth factor 18
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ORF