Synthetic Peptides in Cancer Immunotherapy Development

Cancer immunotherapies re-direct and strengthen cellular immunity to target specific tumor antigens more effectively. To this end, discovery and development strategies focus on identifying and validating novel tumor-specific antigens or neoantigens. Cancer vaccines and adoptive T-cell transfer are predominant immunotherapy modalities leveraging neoantigens. These neoantigen-based immunotherapies are frequently patient-specific.

Significant discovery efforts precede the selection of neoantigens in support of adoptive T-cell therapy or vaccine development. Synthetic peptides are critical throughout the long immunotherapy discovery, development, manufacturing, and immune response monitoring workflow.

Explore the essential roles of synthetic peptides in:

• Neoantigen Target Discovery
• Cancer Vaccine Development Workflows
• Development of Antigen-Specific T-Cell Therapies
  • Identifying and isolating neoepitope-specific T cells
  • Manufacturing T-cell immunotherapies
• Immune Response Monitoring