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About the Cytokine Signaling in Immune system pathway
Cytokines are small proteins that regulate and mediate immunity, inflammation, and hematopoiesis. They are secreted in response to immune stimuli, and usually act briefly, locally, at very low concentrations. Cytokines bind to specific membrane receptors, which then signal the cell via second messengers, to regulate cellular activity.
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Gene Symbol | Full Name |
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ACTN2 | actinin, alpha 2 |
ADAR | adenosine deaminase, RNA-specific |
ANGPT1 | angiopoietin 1 |
BIRC2 | baculoviral IAP repeat containing 2 |
BIRC3 | baculoviral IAP repeat containing 3 |
FASLG | Fas ligand (TNF superfamily, member 6) |
ARAF | A-Raf proto-oncogene, serine/threonine kinase |
ARRB1 | arrestin, beta 1 |
ARRB2 | arrestin, beta 2 |
B2M | beta-2-microglobulin |
TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
BRAF | B-Raf proto-oncogene, serine/threonine kinase |
BST2 | bone marrow stromal cell antigen 2 |
BTC | betacellulin |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
CALM2 | calmodulin 2 (phosphorylase kinase, delta) |
CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
CAMK2D | calcium/calmodulin-dependent protein kinase II delta |
CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
CASP1 | caspase 1, apoptosis-related cysteine peptidase |
CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
CD27 | CD27 molecule |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
CD40LG | CD40 ligand |
CD44 | CD44 molecule (Indian blood group) |
CD70 | CD70 molecule |
CHUK | conserved helix-loop-helix ubiquitous kinase |
CISH | cytokine inducible SH2-containing protein |
MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
CSH1 | chorionic somatomammotropin hormone 1 (placental lactogen) |
CSHL1 | chorionic somatomammotropin hormone-like 1 |
CSK | c-src tyrosine kinase |
DLG4 | discs, large homolog 4 (Drosophila) |
HBEGF | heparin-binding EGF-like growth factor |
DUSP1 | dual specificity phosphatase 1 |
DUSP2 | dual specificity phosphatase 2 |
DUSP4 | dual specificity phosphatase 4 |
DUSP5 | dual specificity phosphatase 5 |
DUSP6 | dual specificity phosphatase 6 |
DUSP7 | dual specificity phosphatase 7 |
DUSP8 | dual specificity phosphatase 8 |
DUSP9 | dual specificity phosphatase 9 |
EDA | ectodysplasin A |
EGF | epidermal growth factor |
EGFR | epidermal growth factor receptor |
EGR1 | early growth response 1 |
EIF4A1 | eukaryotic translation initiation factor 4A1 |
EIF4A2 | eukaryotic translation initiation factor 4A2 |
EIF4E | eukaryotic translation initiation factor 4E |
EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 |
EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
ERBB4 | erb-b2 receptor tyrosine kinase 4 |
EREG | epiregulin |
PTK2B | protein tyrosine kinase 2 beta |
FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
FGA | fibrinogen alpha chain |
FGB | fibrinogen beta chain |
FGF1 | fibroblast growth factor 1 (acidic) |
FGF2 | fibroblast growth factor 2 (basic) |
FGF3 | fibroblast growth factor 3 |
FGF4 | fibroblast growth factor 4 |
FGF5 | fibroblast growth factor 5 |
FGF6 | fibroblast growth factor 6 |
FGF7 | fibroblast growth factor 7 |
FGF8 | fibroblast growth factor 8 (androgen-induced) |
FGF9 | fibroblast growth factor 9 |
FGF10 | fibroblast growth factor 10 |
FGFR1 | fibroblast growth factor receptor 1 |
FGFR3 | fibroblast growth factor receptor 3 |
FGFR2 | fibroblast growth factor receptor 2 |
FGFR4 | fibroblast growth factor receptor 4 |
FGG | fibrinogen gamma chain |
FLNB | filamin B, beta |
FN1 | fibronectin 1 |
FYN | FYN proto-oncogene, Src family tyrosine kinase |
IFI6 | interferon, alpha-inducible protein 6 |
GBP1 | guanylate binding protein 1, interferon-inducible |
GBP2 | guanylate binding protein 2, interferon-inducible |
GBP3 | guanylate binding protein 3 |
GH1 | growth hormone 1 |
GH2 | growth hormone 2 |
GHR | growth hormone receptor |
GRB2 | growth factor receptor-bound protein 2 |
RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 |
GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D |
HCK | HCK proto-oncogene, Src family tyrosine kinase |