The clinical study of immune checkpoint proteins achieved great success, making immunotherapy a promising method to treat cancer. Immune checkpoints are involved in a series of immunomodulatory pathways that can either co-stimulate or co-inhibit the immune response. Co-stimulatory immune checkpoints enhance the body's immune response against pathogens. Co-inhibitory immune-checkpoints can negatively regulate T cell's activity to protect against pro-inflammatory reactions. Targets, such as PD-1, PD-L1, B7, CD28, TIM and CD226, are very hot in cancer treatment.
GenScript immune checkpoint recombinant proteins passed a variety of activity testing and are featured with high purity and batch to batch stability. They are used as immunogens for the production of GenScript immune checkpoint antibodies.
Application
- Modulate immune responses
- Identify binding partners
- Discover novel drugs
- Antibody production
Product Overview
| ligand/ receptor | Product | Cat.no |
|---|---|---|
| 4-1BB | 4-1BB (CD137) Fc Chimera, Human | Z03382 |
| B7-1 | B7-1(CD80) Fc Chimera, Human | Z03409 |
| B7-2 | B7-2/CD86 Fc Chimera, Human | Z03416 |
| B7-2/CD86 Fc His, Human | Z03452 | |
| B7-H2 | B7-H2/ICOSLG Fc Chimera, Human | Z03414 |
| B7-H2/ICOSLG, His, Human | Z03415 | |
| B7-H3 | B7-H3 Fc Chimera, Human | Z03426 |
| B7-H3, His, Human | Z03427 | |
| CD19 | CD19 Fc Chimera, Human | Z03407 |
| CD25 | CD25/IL-2Rα Fc Chimera, Human | Z03400 |
| CD28 | CD28 Fc Chimera, Human | Z03413 |
| CD40L | CD40L/CD154/TRAP, Human | Z02022 |
| sCD40L, Human | Z02727 | |
| CD47 | CD47 Fc Chimera, Human | Z03418 |
| CD47, His, Human | Z03419 | |
| CTLA4 | CTLA-4 Fc Chimera, Human | Z03373 |
| GITR | GITR Ligand Fc Chimera, Human | Z03446 |
| GITR Fc Chimera, Human | Z03440 | |
| HVEM | HVEM-Fc, Human | Z03224 |
| OX40 | OX40/TNFRSF4, His, Human | Z03438 |
| PD-1 | PD-1 Fc Chimera, Human | Z03370 |
| PD-1, His, Human | Z03424 | |
| PD-L1 | PD-L1 Fc Chimera, Human | Z03371 |
| PD-L1, His, Human | Z03425 | |
| PD-L2 | PD-L2 Fc Chimera, Human | Z03417 |
| PVR | PVR/CD155 Fc Chimera, Human | Z03435 |
| PVR/CD155, His, Human | Z03436 | |
| SIRP | SIRPα Fc Chimera, Human | Z03420 |
| SIRPα, His, Human | Z03421 | |
| TIGIT | TIGIT Fc Chimera, Human | Z03439 |
| TIM3 | TIM-3 Fc Chimera, Human | Z03392 |
| TIM-3 Fc Chimera, Mouse | Z03401 | |
| TIM-3, His, Mouse | Z03402 |
Related Products
Find more Epitope Tag Antibodies
| Cat. No. | Product Name | Quantity | Price |
|---|---|---|---|
A01797-40 |
Human IgG (Fc) Antibody, mAb, Mouse - 40 μg |
$99.00 |
|
A00186-40 |
THE™ His Tag Antibody, mAb, Mouse - 40 μg |
$180.00 |
|
A00186-200 |
THE™ His Tag Antibody, mAb, Mouse - 200 μg(5x40μg) |
$675.00 |
|
A01620 |
THE™ His Tag Antibody [FITC], mAb, Mouse - 100 μg |
$410.00 |
|
L00210 |
Protein A Resin - 5 ml Resin (Total 10 ml) |
$107.80 |
|
L00223-500 |
High Affinity Ni-Charged Resin - 500 ml Resin (Total 1000 ml) |
$2480.00 |
|
L00223-50 |
High Affinity Ni-Charged Resin - 50 ml |
$1200.00 |
|
L00223-25 |
High Affinity Ni-Charged Resin - 25 ml Resin (Total 50 ml) |
$168.00 |
|
L00223-10 |
High Affinity Ni-Charged Resin - 10 ml Resin (Total 20 ml) |
$80.00 |
