ERBB2 cDNA ORF clone, Felis catus(domestic cat)

Gene
Clones
gRNAs

Summary

Gene Symbol	ERBB2
Entrez Gene ID	751824
Full Name	erb-b2 receptor tyrosine kinase 2
Synonyms	HER2,erb2
Gene Type	protein-coding
Organism	Felis catus(domestic cat)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001048163.1	NP_001041628.1	receptor tyrosine-protein kinase erbB-2 precursor
XM_006940248.3	XP_006940310.1	receptor tyrosine-protein kinase erbB-2 isoform X1
XM_006940248.4	XP_006940310.2	receptor tyrosine-protein kinase erbB-2 isoform X1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status.
Soares M, Ribeiro R, Najmudin S, Gameiro A, Rodrigues R, Cardoso F, Ferreira F
Oncotarget7(14)17314-26(2016 Apr)

Changes in c-erbB-2 Immunoexpression in Feline Endometrial Adenocarcinomas.
Saraiva AL, Payan-Carreira R, Gärtner F, Faria F, Lourenço LM, Pires MA
Reproduction in domestic animals = Zuchthygiene51(1)33-9(2016 Feb)

Molecular phenotype of primary mammary tumours and distant metastases in female dogs and cats.
Beha G, Muscatello LV, Brunetti B, Asproni P, Millanta F, Poli A, Benazzi C, Sarli G
Journal of comparative pathology150(2-3)194-7(2014 Feb-Apr)

Sequence variants and haplotype analysis of cat ERBB2 gene: a survey on spontaneous cat mammary neoplastic and non-neoplastic lesions.
Santos S, Bastos E, Baptista CS, Sá D, Caloustian C, Guedes-Pinto H, Gärtner F, Gut IG, Chaves R
International journal of molecular sciences13(3)2783-800(2012)

Spontaneous feline mammary carcinoma is a model of HER2 overexpressing poor prognosis human breast cancer.
De Maria R, Olivero M, Iussich S, Nakaichi M, Murata T, Biolatti B, Di Renzo MF
Cancer research65(3)907-12(2005 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ERBB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ERBB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFb24724	NM_001048163.1 Latest version!	Felis catus erb-b2 receptor tyrosine kinase 2 (ERBB2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OFb19071	XM_006940248.3 Latest version!	Felis catus erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OFb64284	XM_006940248.4 Latest version!	Felis catus erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ERBB2 ( NM_001048163.1 ) cDNA ORF clone, Felis catus(domestic cat) -> NP_001041628.1 Felis catus erb-b2 receptor tyrosine kinase 2 (ERBB2), mRNA.

Price & Availability↑

CloneID	OFb24724
Clone ID Related Accession (Same CDS sequence)	NM_001048163.1
Accession Version	NM_001048163.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3783bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1498233600000
Organism	Felis catus(domestic cat)
Product	receptor tyrosine-protein kinase erbB-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY702651.1. ##Evidence-Data-START## Transcript exon combination :: AY702651.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01831871, SAMN01831872 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCTGG CGGCCTGGTG CCGCTGGGGG CTCCTCCTCG CCCTCCTGCC CTCCGGAGCC 
ACGGGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTGC GGCTCCCAGC CAGTCCCGAG 
ACCCACCTGG ACATGCTCCG CCACCTCTAC CAGGGCTGTC AAGTGGTACA GGGCAACCTG 
GAGCTCACCT ACCTGCATGC CAATGCCAGC CTCTCCTTCC TGCAGGATAT CCAGGAGGTG 
CAAGGCTATG TGCTCATTGC CCACAACCAA GTGAAACAGG TCCCACTGCA GAGGCTACGA 
ATCGTGCGAG GCACCCAGCT CTTTGAGGAC AACTACGCCC TGGCCGTGCT GGACAATGGA 
GACCCGCTGA AGAATACCAC CCCTGTCACA GGGGCCTCCC CAGGAGGCCT GCGGGAGCTG 
CAGCTTCGAA GCCTCACAGA GATCTTGAAA GGAGGGGTCT TGATCCAGCG GAACCCCCAG 
CTCTGCTACC AGGACACGAT TTTGTGGAAG GACATCTTCC ACAAGAACAA CCAGCTGGCT 
CTCACACTGA TAGACACCAA CCGCTCTCGG GCCTGCCACC CCTGTTCTCC GATGTGTGAG 
GGCTCCCGCT GCTGGGGAGA GAGTTCTGAG GATTGTCAGA GCCTGACGCG CACTGTCTGT 
GCCGGTGGCT GTGCCCGCTG CAAGGGGCCA CTGCCCACTG ACTGCTGCCA TGAGCAGTGT 
GCTGCCGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTCCA CTTCAACCAC 
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACAGA CACGTTTGAG 
TCCATGCCCA ATCCCGAGGG CCGGTATACA TTCGGCGCCA GCTGTGTGAC TGCCTGTCCC 
TACAACTACC TTTCTACGGA CGTGGGATCC TGCACCCTGG TCTGTCCCCT GAACAACCAA 
GAGGTGACAG CTGAGGATGG AACACAGCGG TGTGAGAAAT GCAGCAAGCC CTGTGCCCGA 
GTGTGCTACG GCCTAGGCAT GGAGCACCTG CGGGAGGCGA GGGCAGTCAC CAGTGCCAAC 
ATCCAAGAAT TTGTCGGCTG CAAGAAGATC TTTGGGAGCC TGGCGTTTCT GCCAGGGAGC 
TTTGAGGGGG ACCCAGCCTC CAACACTGCC CCCCTGCAGC CTGAGCAGCT CAGAGTGTTT 
GAGGCTCTGG AGGAGATTAC AGGTTACCTG TACATCTCAG CGTGGCCAGA CAGCTTGCCT 
AACCTCAGTG TCTTCCAGAA CCTCAGAGTA ATCCGGGGCC GAGTTCTGCA TGACGGTGCT 
TACTCGCTGA CCCTTCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC GCTGCGGGAG 
CTGGGCAGTG GGCTGGCCCT CATCCACCGC AACTCCCGCC TCTGCTTCGT ACACACGGTG 
CCCTGGGACC AGCTCTTCCG GAACCCCCAC CAGGCCCTGC TCCACAGCGC CAACCGGCCA 
GAGGACGAGT GCCCGGGTGA GGGCCTGGCC TGCTATCCGC TGTGCGCCCA CGGGCACTGC 
TGGGGTCCGG GACCCACCCA TTGTGTCAAC TGCAGCCAGT TCCTTCCGGG CCAGGAATGC 
GTGGAGGAAT GCCGAGTACT GCAGGGGCTG CCCCGGGAGT ATGTGAAGGA TAGGTTCTGT 
CTGCCATGCC ACCCGGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGCTT GGGCTCGGAA 
GCTGACCAGT GTGTGGCCTG TGCCCACTAC AAGGACCCTC CTTTCTGTGT GGCTCGCTGC 
TCCAGTGGGG TGAAACCTGA CCTCTCCTTC ATGCCCATCT GGAAGTTCGC AGATGAGGAG 
GGCACGTGCC AGCCATGCCC CATCAACTGC ACCCACTCCT GTGCGGACCT GGACGAGAAG 
GGCTGCCCCG CCGAGCAGAG AGCCAGCCCT GTGACGTCCA TCATTGCCGC TGTGGTGGGC 
ATTCTGCTGG TCGTGGTTGT GGGGCTGGTC CTTGGCATCC TGATCAAGCG AAGGCGGCAG 
AAGATCCGGA AGTACACGAT GCGGAGGCTG CTGCAGGAGA CGGAGCTGGT GGAGCCCCTG 
ACGCCTAGTG GAGCCATGCC CAACCAGGCT CAGATGCGAA TCCTGAAAGA AACAGAGCTG 
AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT TTTGGCACTG TCTACAAGGG CATCTGGATC 
CCTGACGGGG AAAATGTGAA AATCCCAGTG GCCATCAAAG TGTTGAGGGA AAATACATCT 
CCCAAAGCCA ACAAAGAAAT CTTGGACGAA GCGTATGTGA TGGCTGGCGT GGGCTCCCCA 
TATGTGTCTC GCCTTCTGGG CATCTGCCTG ACATCCACGG TGCAGTTGGT GACACAGCTT 
ATGCCTTATG GCTGCCTCTT AGACCATGTC CGAGAACACC GTGGGCGCCT AGGCTCCCAG 
GACCTGCTGA ACTGGTGTGT GCAGATTGCC AAGGGGATGA GCTACTTGGA GGATGTTCGG 
CTCGTGCACA GGGACCTGGC TGCCCGGAAC GTGCTGGTCA AGAGTCCCAA CCACGTCAAG 
ATTACAGATT TTGGGCTGGC TCGGCTGCTG GACATTGACG AGACAGAGTA CCATGCCGAT 
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCA TTCTCCGCCG GCGGTTCACC 
CATCAGAGTG ACGTGTGGAG CTACGGTGTG ACTGTATGGG AACTGATGAC TTTTGGGGCC 
AAACCTTATG ATGGGATCCC AGCCCGGGAG ATTCCTGACC TGCTGGAGAA GGGGGAACGG 
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA ATGTTGGATG 
ATAGACTCTG AATGTCGGCC ACGTTTCCGG GAGCTGGTGG CCGAATTCTC CCGTATGGCC 
AGGGACCCCC AGCGCTTTGT GGTCATCCAG AATGAGGACT TGGGCCCAGC GAGTCCCTTG 
GACAGCACTT TCTACCGTTC ACTGCTGGAG GATGAGGACA TGGGAGACCT GGTGGATGCT 
GAGGAGTACC TGGTACCCCA GCAGGGTTTC TTCTGCCCAG ACCCTGCCCC AGGCGCTGGG 
GGCACAGCCC ACCGCAGACA CCGCAGCTCA TCCACCAGGA GTGGCGGTGG TGAGCTGACA 
CTGGGGCTGG AGCCCTCCGA GGAAGAGCCT CCCAAGTCTC CACTGGCACC CTCAGAAGGG 
GCTGGCTCTG ATGTGTTTGA TGGCGACTTG GGAATGGGGG CAGCCAAGGG GCTGCAGAGC 
CTTTCCCCAC AGGACCCCAG CCCTCTACAG CGGTACAGTG AGGATCCTAC CGTACCCCTA 
CCCCCTGAGA CTGATGGCTA CGTTGCCCCC CTGACCTGCA GTCCCCAGCC TGAATACGTG 
AACCAGCCAG AGGTTTGGCC AAAGCCCCCA TCGCCCTTAG AAGGCCCTCT GCCTCCTTCT 
CGACCTGCCG GTGCCACTCT GGAAAGGCCC AAGACTCTGT CCCCCAAGAC TCTTTCCCCC 
GGCAAGAATG GGGTTGTCAA AGACGTTTTT GCCTTTGGGG GTGCTGTGGA GAACCCCGAG 
TACTTGGCAC CCCGGGGCAG GGCTGCCCCT CAGCCTCACC CTCCTCCAGC CTTCAGCCCA 
GCCTTTGACA ACCTCTATTA CTGGGACCAG GACACATCTG AGCGGGGCTC TCCACCCAGC 
ACCTTTGAAG GGACCCCTAC AGCAGAGAAC CCCGAATACC TGGGGCTGGA CGTGCCAGTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001041628.1
CDS	1..3783
Translation	MELAAWCRWGLLLALLPSGATGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLHANASLSFLQDIQEVQGYVLIAHNQVKQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLKNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCEGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSANIQEFVGCKKIFGSLAFLPGSFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLPNLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNSRLCFVHTVPWDQLFRNPHQALLHSANRPEDECPGEGLACYPLCAHGHCWGPGPTHCVNCSQFLPGQECVEECRVLQGLPREYVKDRFCLPCHPECQPQNGSVTCLGSEADQCVACAHYKDPPFCVARCSSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDEKGCPAEQRASPVTSIIAAVVGILLVVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDEDMGDLVDAEEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEGAGSDVFDGDLGMGAAKGLQSLSPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYVNQPEVWPKPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGGAVENPEYLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDTSERGSPPSTFEGTPTAENPEYLGLDVPV

Target ORF information:

RefSeq Version	NM_001048163.1
Organism	Felis catus(domestic cat)
Definition	Felis catus erb-b2 receptor tyrosine kinase 2 (ERBB2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001048163.1

ORF Insert Sequence:

ATGGAGCTGG CGGCCTGGTG CCGCTGGGGG CTCCTCCTCG CCCTCCTGCC CTCCGGAGCC 
ACGGGCACCC AAGTGTGCAC CGGCACAGAC ATGAAGCTGC GGCTCCCAGC CAGTCCCGAG 
ACCCACCTGG ACATGCTCCG CCACCTCTAC CAGGGCTGTC AAGTGGTACA GGGCAACCTG 
GAGCTCACCT ACCTGCATGC CAATGCCAGC CTCTCCTTCC TGCAGGATAT CCAGGAGGTG 
CAAGGCTATG TGCTCATTGC CCACAACCAA GTGAAACAGG TCCCACTGCA GAGGCTACGA 
ATCGTGCGAG GCACCCAGCT CTTTGAGGAC AACTACGCCC TGGCCGTGCT GGACAATGGA 
GACCCGCTGA AGAATACCAC CCCTGTCACA GGGGCCTCCC CAGGAGGCCT GCGGGAGCTG 
CAGCTTCGAA GCCTCACAGA GATCTTGAAA GGAGGGGTCT TGATCCAGCG GAACCCCCAG 
CTCTGCTACC AGGACACGAT TTTGTGGAAG GACATCTTCC ACAAGAACAA CCAGCTGGCT 
CTCACACTGA TAGACACCAA CCGCTCTCGG GCCTGCCACC CCTGTTCTCC GATGTGTGAG 
GGCTCCCGCT GCTGGGGAGA GAGTTCTGAG GATTGTCAGA GCCTGACGCG CACTGTCTGT 
GCCGGTGGCT GTGCCCGCTG CAAGGGGCCA CTGCCCACTG ACTGCTGCCA TGAGCAGTGT 
GCTGCCGGCT GCACGGGCCC CAAGCACTCT GACTGCCTGG CCTGCCTCCA CTTCAACCAC 
AGTGGCATCT GTGAGCTGCA CTGCCCAGCC CTGGTCACCT ACAACACAGA CACGTTTGAG 
TCCATGCCCA ATCCCGAGGG CCGGTATACA TTCGGCGCCA GCTGTGTGAC TGCCTGTCCC 
TACAACTACC TTTCTACGGA CGTGGGATCC TGCACCCTGG TCTGTCCCCT GAACAACCAA 
GAGGTGACAG CTGAGGATGG AACACAGCGG TGTGAGAAAT GCAGCAAGCC CTGTGCCCGA 
GTGTGCTACG GCCTAGGCAT GGAGCACCTG CGGGAGGCGA GGGCAGTCAC CAGTGCCAAC 
ATCCAAGAAT TTGTCGGCTG CAAGAAGATC TTTGGGAGCC TGGCGTTTCT GCCAGGGAGC 
TTTGAGGGGG ACCCAGCCTC CAACACTGCC CCCCTGCAGC CTGAGCAGCT CAGAGTGTTT 
GAGGCTCTGG AGGAGATTAC AGGTTACCTG TACATCTCAG CGTGGCCAGA CAGCTTGCCT 
AACCTCAGTG TCTTCCAGAA CCTCAGAGTA ATCCGGGGCC GAGTTCTGCA TGACGGTGCT 
TACTCGCTGA CCCTTCAAGG GCTGGGCATC AGCTGGCTGG GGCTGCGCTC GCTGCGGGAG 
CTGGGCAGTG GGCTGGCCCT CATCCACCGC AACTCCCGCC TCTGCTTCGT ACACACGGTG 
CCCTGGGACC AGCTCTTCCG GAACCCCCAC CAGGCCCTGC TCCACAGCGC CAACCGGCCA 
GAGGACGAGT GCCCGGGTGA GGGCCTGGCC TGCTATCCGC TGTGCGCCCA CGGGCACTGC 
TGGGGTCCGG GACCCACCCA TTGTGTCAAC TGCAGCCAGT TCCTTCCGGG CCAGGAATGC 
GTGGAGGAAT GCCGAGTACT GCAGGGGCTG CCCCGGGAGT ATGTGAAGGA TAGGTTCTGT 
CTGCCATGCC ACCCGGAGTG TCAGCCCCAG AATGGCTCAG TGACCTGCTT GGGCTCGGAA 
GCTGACCAGT GTGTGGCCTG TGCCCACTAC AAGGACCCTC CTTTCTGTGT GGCTCGCTGC 
TCCAGTGGGG TGAAACCTGA CCTCTCCTTC ATGCCCATCT GGAAGTTCGC AGATGAGGAG 
GGCACGTGCC AGCCATGCCC CATCAACTGC ACCCACTCCT GTGCGGACCT GGACGAGAAG 
GGCTGCCCCG CCGAGCAGAG AGCCAGCCCT GTGACGTCCA TCATTGCCGC TGTGGTGGGC 
ATTCTGCTGG TCGTGGTTGT GGGGCTGGTC CTTGGCATCC TGATCAAGCG AAGGCGGCAG 
AAGATCCGGA AGTACACGAT GCGGAGGCTG CTGCAGGAGA CGGAGCTGGT GGAGCCCCTG 
ACGCCTAGTG GAGCCATGCC CAACCAGGCT CAGATGCGAA TCCTGAAAGA AACAGAGCTG 
AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT TTTGGCACTG TCTACAAGGG CATCTGGATC 
CCTGACGGGG AAAATGTGAA AATCCCAGTG GCCATCAAAG TGTTGAGGGA AAATACATCT 
CCCAAAGCCA ACAAAGAAAT CTTGGACGAA GCGTATGTGA TGGCTGGCGT GGGCTCCCCA 
TATGTGTCTC GCCTTCTGGG CATCTGCCTG ACATCCACGG TGCAGTTGGT GACACAGCTT 
ATGCCTTATG GCTGCCTCTT AGACCATGTC CGAGAACACC GTGGGCGCCT AGGCTCCCAG 
GACCTGCTGA ACTGGTGTGT GCAGATTGCC AAGGGGATGA GCTACTTGGA GGATGTTCGG 
CTCGTGCACA GGGACCTGGC TGCCCGGAAC GTGCTGGTCA AGAGTCCCAA CCACGTCAAG 
ATTACAGATT TTGGGCTGGC TCGGCTGCTG GACATTGACG AGACAGAGTA CCATGCCGAT 
GGGGGCAAGG TGCCCATCAA GTGGATGGCG CTGGAGTCCA TTCTCCGCCG GCGGTTCACC 
CATCAGAGTG ACGTGTGGAG CTACGGTGTG ACTGTATGGG AACTGATGAC TTTTGGGGCC 
AAACCTTATG ATGGGATCCC AGCCCGGGAG ATTCCTGACC TGCTGGAGAA GGGGGAACGG 
CTGCCCCAGC CCCCCATCTG CACCATTGAT GTCTACATGA TCATGGTCAA ATGTTGGATG 
ATAGACTCTG AATGTCGGCC ACGTTTCCGG GAGCTGGTGG CCGAATTCTC CCGTATGGCC 
AGGGACCCCC AGCGCTTTGT GGTCATCCAG AATGAGGACT TGGGCCCAGC GAGTCCCTTG 
GACAGCACTT TCTACCGTTC ACTGCTGGAG GATGAGGACA TGGGAGACCT GGTGGATGCT 
GAGGAGTACC TGGTACCCCA GCAGGGTTTC TTCTGCCCAG ACCCTGCCCC AGGCGCTGGG 
GGCACAGCCC ACCGCAGACA CCGCAGCTCA TCCACCAGGA GTGGCGGTGG TGAGCTGACA 
CTGGGGCTGG AGCCCTCCGA GGAAGAGCCT CCCAAGTCTC CACTGGCACC CTCAGAAGGG 
GCTGGCTCTG ATGTGTTTGA TGGCGACTTG GGAATGGGGG CAGCCAAGGG GCTGCAGAGC 
CTTTCCCCAC AGGACCCCAG CCCTCTACAG CGGTACAGTG AGGATCCTAC CGTACCCCTA 
CCCCCTGAGA CTGATGGCTA CGTTGCCCCC CTGACCTGCA GTCCCCAGCC TGAATACGTG 
AACCAGCCAG AGGTTTGGCC AAAGCCCCCA TCGCCCTTAG AAGGCCCTCT GCCTCCTTCT 
CGACCTGCCG GTGCCACTCT GGAAAGGCCC AAGACTCTGT CCCCCAAGAC TCTTTCCCCC 
GGCAAGAATG GGGTTGTCAA AGACGTTTTT GCCTTTGGGG GTGCTGTGGA GAACCCCGAG 
TACTTGGCAC CCCGGGGCAG GGCTGCCCCT CAGCCTCACC CTCCTCCAGC CTTCAGCCCA 
GCCTTTGACA ACCTCTATTA CTGGGACCAG GACACATCTG AGCGGGGCTC TCCACCCAGC 
ACCTTTGAAG GGACCCCTAC AGCAGAGAAC CCCGAATACC TGGGGCTGGA CGTGCCAGTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERBB2 ( XM_006940248.3 ) cDNA ORF clone, Felis catus(domestic cat) -> XP_006940310.1 Felis catus erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OFb19071
Clone ID Related Accession (Same CDS sequence)	XM_006940248.3
Accession Version	XM_006940248.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1482854400000
Organism	Felis catus(Domestic cat)
Product	receptor tyrosine-protein kinase erbB-2 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_018736.2) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 29, 2016 this sequence version replaced XM_006940248.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Felis catus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGC GGCTCCCAGC CAGTCCCGAG ACCCACCTGG ACATGCTCCG CCACCTCTAC 
CAGGGCTGTC AAGTGGTACA GGGCAACCTG GAGCTCACCT ACCTGCATGC CAATGCCAGC 
CTCTCCTTCC TGCAGGATAT CCAGGAGGTG CAAGGCTATG TGCTCATTGC CCACAACCAA 
GTGAAACAGG TCCCACTGCA GAGGCTACGA ATCGTGCGAG GCACCCAGCT CTTTGAGGAC 
AACTACGCCC TGGCCGTGCT GGACAACGGA GACCCACTGG ACAGTGGCAC CCCTGCTACA 
GGGACTGCCC TAGGAGGGCT GCGGGAGCTG CAGCTCCGAA GCCTCACAGA GATCCTGAAG 
GGAGGGGTCC TCATTCAGCG GAACCCGCAG CTCTGCCACC AGGACACGAT TCTGTGGAAG 
GACATCTTCC ACAAGAACAA CCAGCTGGCC CTCATGCTGA TAGACACCAA CCGCTCTCGG 
GCCTGCCAAC CCTGTTCTCC AGCTTGTAAA GACTCCCACT GCTGGGGAGC AAGTTCCGGG 
GACTGTCAGA GCTTGACTCG AACTGTCTGT GCTGGTGGCT GTGCCCGCTG CAAGGGCCCG 
CAGCCCACCG ACTGCTGCCA CGAGCAGTGT GCTGCTGGCT GCACGGGCCC CAAGCATTCT 
GACTGCCTGG CCTGCCTCCA CTTCAACCAC AGTGGCATCT GTGAGCTGCA CTGCCCAGCC 
CTGGTCACCT ACAACACGGA CACCTTCGAA TCCATGCCCA ACCCTGAGGG CCGTTATACC 
TTCGGTGCCA GCTGTGTGAC TGCCTGTCCC TACAACTACC TGTCTACGGA CGTGGGATCC 
TGCACCCTGG TCTGTCCCCT GAACAACCAA GAGGTGACAG CTGAGGATGG AACACAGCGG 
TGTGAGAAAT GCAGCAAGCC CTGTGCCCGA GTGTGCTACG GCCTAGGCAT GGAGCACCTG 
CGGGAGGCGA GGGCAGTCAC CAGTGCCAAC ATCCAAGAAT TTGTCGGCTG CAAGAAGATC 
TTTGGGAGCC TGGCGTTTCT GCCAGAGAGC TTTGAGGGGG ACCCAGCCTC CAACACTGCC 
CCCCTGCAGC CTGAGCAGCT CAGAGTGTTT GAGGCTCTGG AGGAGATTAC AGGTTACCTG 
TACATCTCAG CGTGGCCAGA CAGCTTGCCT AACCTCAGTG TCTTCCAGAA CCTCAGAGTG 
ATCCGGGGCC GAGTTCTGCA TGACGGTGCT TACTCGCTGA CCCTTCAAGG GCTGGGCATC 
AGCTGGCTGG GGCTGCGCTC GCTGCGGGAG CTGGGCAGTG GGCTGGCCCT CATCCACCGC 
AACTCCCGCC TCTGCTTCGT ACACACGGTG CCCTGGGACC AGCTCTTCCG GAACCCCCAC 
CAGGCCCTGC TCCACAGCGC CAACCGGCCA GAGGACGAGT GCGCGGGTGA GGGCCTGGCC 
TGCTATCCGC TGTGTGCCCA CGGGCACTGC TGGGGTCCGG GACCCACCCA GTGTGTCAAC 
TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC GTGGAGGAAT GCCGAGTATT GCAGGGGCTT 
CCCCGGGAGT ATGTGAAGGA TAGGTTCTGT CTGCCATGCC ACCCGGAGTG TCAGCCCCAG 
AATGGCTCAG TGACCTGCTT GGGCTCGGAA GCTGACCAGT GTGTGGCCTG TGCCCACTAC 
AAGGACCCTC CTTTCTGTGT GGCTCGCTGC CCCAGTGGGG TGAAACCTGA CCTCTCCTTC 
ATGCCCATCT GGAAGTTCGC AGATGAGGAG GGCACGTGCC AGCCATGCCC CATCAACTGC 
ACCCACTCCT GTGCGGACCT GGACGAGAAG GGCTGCCCCG CTGAGCAGAG AGCCAGCCCT 
GTGACGTCCA TCATTGCTGC TGTGGTGGGC ATTCTGCTGG TCGTGGTTGT GGGGCTGGTC 
CTTGGCATCC TAATCAAGCG AAGGCGGCAG AAGATCCGGA AGTACACGAT GCGGAGGCTG 
CTGCAGGAGA CGGAGCTGGT GGAGCCCCTG ACGCCTAGTG GAGCCATGCC CAACCAGGCT 
CAGATGCGAA TCCTGAAAGA AACAGAGCTG AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT 
TTTGGCACTG TCTACAAGGG CATCTGGATC CCTGATGGGG AAAATGTGAA AATCCCAGTG 
GCCATCAAAG TGTTGAGGGA AAATACATCT CCCAAAGCCA ACAAAGAAAT CTTGGACGAA 
GCATATGTGA TGGCTGGCGT GGGCTCCCCA TATGTGTCTC GCCTTCTGGG CATCTGTCTG 
ACATCCACCG TGCAGTTGGT GACACAGCTT ATGCCTTATG GCTGCCTCTT AGACCATGTC 
CGAGAACACC GTGGGCGCCT AGGCTCCCAG GACCTGCTGA ACTGGTGTGT GCAGATTGCC 
AAGGGGATGA GCTACTTGGA GGATGTTCGG CTCGTGCACA GGGACCTGGC TGCCCGGAAC 
GTGCTGGTCA AGAGTCCCAA CCACGTCAAG ATTACAGATT TTGGGCTGGC TCGGCTGCTG 
GACATTGACG AGACAGAGTA CCATGCCGAT GGGGGCAAGG TGCCCATCAA GTGGATGGCG 
CTGGAGTCCA TTCTCCGCCG GCGGTTCACC CATCAGAGTG ACGTGTGGAG CTACGGTGTG 
ACTGTATGGG AACTGATGAC TTTTGGGGCC AAACCTTATG ATGGGATCCC AGCCCGGGAG 
ATTCCTGACC TGCTGGAGAA GGGGGAACGG CTGCCCCAGC CCCCCATCTG CACCATTGAT 
GTCTACATGA TCATGGTCAA ATGTTGGATG ATAGACTCTG AATGTCGGCC ACGTTTCCGG 
GAGCTGGTGG CCGAATTCTC CCGGATGGCC AGGGACCCCC AGCGCTTTGT GGTCATCCAG 
AATGAGGACT TGGGCCCAGC GAGTCCCCTG GACAGCACTT TCTACCGTTC ACTGCTGGAG 
GATGAGGACA TGGGAGACCT GGTGGATGCT GAGGAGTACC TGGTACCCCA GCAGGGTTTC 
TTCTGCCCAG ACCCTGCCCC AGGCGCCGGG GGCACAGCCC ACCGCAGACA CCGCAGCTCA 
TCCACCAGGA GTGGCGGTGG TGAGCTGACA CTGGGGCTGG AGCCCTCCGA GGAAGAGCCT 
CCCAAGTCTC CACTGGCACC CTCAGAAGGG GCTGGCTCTG ATGTGTTTGA TGGCGACTTG 
GGAATGGGGG CAGCCAAGGG GCTGCAGAGC CTTTCCCCAC AGGACCCCAG CCCTCTACAG 
CGGTACAGTG AGGATCCTAC CGTACCCCTA CCCCCTGAGA CTGATGGCTA CGTTGCCCCC 
CTGACCTGCA GTCCCCAGCC TGAATACGTG AACCAGCCAG AGGTTTGGCC AAAGCCCCCA 
TCGCCCTTAG AAGGCCCTCT GCCTCCTTCT CGACCTGCCG GTGCCACTCT GGAAAGGCCC 
AAGACTCTGT CCCCCAAGAC TCTTTCCCCC GGCAAGAATG GGGTTGTCAA AGACGTTTTT 
GCCTTTGGGG GTGCTGTGGA GAACCCCGAG TACTTGGCAC CCCGGGGCAG GGCTGCCCCT 
CAGCCTCACC CTCCTCCAGC CTTCAGCCCA GCCTTTGACA ACCTCTATTA CTGGGACCAG 
GACACATCTG AGCGGGGCTC TCCACCCAGC ACCTTTGAAG GGACCCCTAC AGCAGAGAAC 
CCCGAATACC TGGGCCTGGA TGTGCCAGTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006940310.1
CDS	43..3735
Translation	MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLHANASLSFLQDIQEVQGYVLIAHNQVKQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLDSGTPATGTALGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLALMLIDTNRSRACQPCSPACKDSHCWGASSGDCQSLTRTVCAGGCARCKGPQPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSANIQEFVGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLPNLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNSRLCFVHTVPWDQLFRNPHQALLHSANRPEDECAGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVKDRFCLPCHPECQPQNGSVTCLGSEADQCVACAHYKDPPFCVARCPSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDEKGCPAEQRASPVTSIIAAVVGILLVVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDEDMGDLVDAEEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEGAGSDVFDGDLGMGAAKGLQSLSPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYVNQPEVWPKPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGGAVENPEYLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDTSERGSPPSTFEGTPTAENPEYLGLDVPV

Target ORF information:

RefSeq Version	XM_006940248.3
Organism	Felis catus(Domestic cat)
Definition	Felis catus erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006940248.3

ORF Insert Sequence:

ATGAAGCTGC GGCTCCCAGC CAGTCCCGAG ACCCACCTGG ACATGCTCCG CCACCTCTAC 
CAGGGCTGTC AAGTGGTACA GGGCAACCTG GAGCTCACCT ACCTGCATGC CAATGCCAGC 
CTCTCCTTCC TGCAGGATAT CCAGGAGGTG CAAGGCTATG TGCTCATTGC CCACAACCAA 
GTGAAACAGG TCCCACTGCA GAGGCTACGA ATCGTGCGAG GCACCCAGCT CTTTGAGGAC 
AACTACGCCC TGGCCGTGCT GGACAACGGA GACCCACTGG ACAGTGGCAC CCCTGCTACA 
GGGACTGCCC TAGGAGGGCT GCGGGAGCTG CAGCTCCGAA GCCTCACAGA GATCCTGAAG 
GGAGGGGTCC TCATTCAGCG GAACCCGCAG CTCTGCCACC AGGACACGAT TCTGTGGAAG 
GACATCTTCC ACAAGAACAA CCAGCTGGCC CTCATGCTGA TAGACACCAA CCGCTCTCGG 
GCCTGCCAAC CCTGTTCTCC AGCTTGTAAA GACTCCCACT GCTGGGGAGC AAGTTCCGGG 
GACTGTCAGA GCTTGACTCG AACTGTCTGT GCTGGTGGCT GTGCCCGCTG CAAGGGCCCG 
CAGCCCACCG ACTGCTGCCA CGAGCAGTGT GCTGCTGGCT GCACGGGCCC CAAGCATTCT 
GACTGCCTGG CCTGCCTCCA CTTCAACCAC AGTGGCATCT GTGAGCTGCA CTGCCCAGCC 
CTGGTCACCT ACAACACGGA CACCTTCGAA TCCATGCCCA ACCCTGAGGG CCGTTATACC 
TTCGGTGCCA GCTGTGTGAC TGCCTGTCCC TACAACTACC TGTCTACGGA CGTGGGATCC 
TGCACCCTGG TCTGTCCCCT GAACAACCAA GAGGTGACAG CTGAGGATGG AACACAGCGG 
TGTGAGAAAT GCAGCAAGCC CTGTGCCCGA GTGTGCTACG GCCTAGGCAT GGAGCACCTG 
CGGGAGGCGA GGGCAGTCAC CAGTGCCAAC ATCCAAGAAT TTGTCGGCTG CAAGAAGATC 
TTTGGGAGCC TGGCGTTTCT GCCAGAGAGC TTTGAGGGGG ACCCAGCCTC CAACACTGCC 
CCCCTGCAGC CTGAGCAGCT CAGAGTGTTT GAGGCTCTGG AGGAGATTAC AGGTTACCTG 
TACATCTCAG CGTGGCCAGA CAGCTTGCCT AACCTCAGTG TCTTCCAGAA CCTCAGAGTG 
ATCCGGGGCC GAGTTCTGCA TGACGGTGCT TACTCGCTGA CCCTTCAAGG GCTGGGCATC 
AGCTGGCTGG GGCTGCGCTC GCTGCGGGAG CTGGGCAGTG GGCTGGCCCT CATCCACCGC 
AACTCCCGCC TCTGCTTCGT ACACACGGTG CCCTGGGACC AGCTCTTCCG GAACCCCCAC 
CAGGCCCTGC TCCACAGCGC CAACCGGCCA GAGGACGAGT GCGCGGGTGA GGGCCTGGCC 
TGCTATCCGC TGTGTGCCCA CGGGCACTGC TGGGGTCCGG GACCCACCCA GTGTGTCAAC 
TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC GTGGAGGAAT GCCGAGTATT GCAGGGGCTT 
CCCCGGGAGT ATGTGAAGGA TAGGTTCTGT CTGCCATGCC ACCCGGAGTG TCAGCCCCAG 
AATGGCTCAG TGACCTGCTT GGGCTCGGAA GCTGACCAGT GTGTGGCCTG TGCCCACTAC 
AAGGACCCTC CTTTCTGTGT GGCTCGCTGC CCCAGTGGGG TGAAACCTGA CCTCTCCTTC 
ATGCCCATCT GGAAGTTCGC AGATGAGGAG GGCACGTGCC AGCCATGCCC CATCAACTGC 
ACCCACTCCT GTGCGGACCT GGACGAGAAG GGCTGCCCCG CTGAGCAGAG AGCCAGCCCT 
GTGACGTCCA TCATTGCTGC TGTGGTGGGC ATTCTGCTGG TCGTGGTTGT GGGGCTGGTC 
CTTGGCATCC TAATCAAGCG AAGGCGGCAG AAGATCCGGA AGTACACGAT GCGGAGGCTG 
CTGCAGGAGA CGGAGCTGGT GGAGCCCCTG ACGCCTAGTG GAGCCATGCC CAACCAGGCT 
CAGATGCGAA TCCTGAAAGA AACAGAGCTG AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT 
TTTGGCACTG TCTACAAGGG CATCTGGATC CCTGATGGGG AAAATGTGAA AATCCCAGTG 
GCCATCAAAG TGTTGAGGGA AAATACATCT CCCAAAGCCA ACAAAGAAAT CTTGGACGAA 
GCATATGTGA TGGCTGGCGT GGGCTCCCCA TATGTGTCTC GCCTTCTGGG CATCTGTCTG 
ACATCCACCG TGCAGTTGGT GACACAGCTT ATGCCTTATG GCTGCCTCTT AGACCATGTC 
CGAGAACACC GTGGGCGCCT AGGCTCCCAG GACCTGCTGA ACTGGTGTGT GCAGATTGCC 
AAGGGGATGA GCTACTTGGA GGATGTTCGG CTCGTGCACA GGGACCTGGC TGCCCGGAAC 
GTGCTGGTCA AGAGTCCCAA CCACGTCAAG ATTACAGATT TTGGGCTGGC TCGGCTGCTG 
GACATTGACG AGACAGAGTA CCATGCCGAT GGGGGCAAGG TGCCCATCAA GTGGATGGCG 
CTGGAGTCCA TTCTCCGCCG GCGGTTCACC CATCAGAGTG ACGTGTGGAG CTACGGTGTG 
ACTGTATGGG AACTGATGAC TTTTGGGGCC AAACCTTATG ATGGGATCCC AGCCCGGGAG 
ATTCCTGACC TGCTGGAGAA GGGGGAACGG CTGCCCCAGC CCCCCATCTG CACCATTGAT 
GTCTACATGA TCATGGTCAA ATGTTGGATG ATAGACTCTG AATGTCGGCC ACGTTTCCGG 
GAGCTGGTGG CCGAATTCTC CCGGATGGCC AGGGACCCCC AGCGCTTTGT GGTCATCCAG 
AATGAGGACT TGGGCCCAGC GAGTCCCCTG GACAGCACTT TCTACCGTTC ACTGCTGGAG 
GATGAGGACA TGGGAGACCT GGTGGATGCT GAGGAGTACC TGGTACCCCA GCAGGGTTTC 
TTCTGCCCAG ACCCTGCCCC AGGCGCCGGG GGCACAGCCC ACCGCAGACA CCGCAGCTCA 
TCCACCAGGA GTGGCGGTGG TGAGCTGACA CTGGGGCTGG AGCCCTCCGA GGAAGAGCCT 
CCCAAGTCTC CACTGGCACC CTCAGAAGGG GCTGGCTCTG ATGTGTTTGA TGGCGACTTG 
GGAATGGGGG CAGCCAAGGG GCTGCAGAGC CTTTCCCCAC AGGACCCCAG CCCTCTACAG 
CGGTACAGTG AGGATCCTAC CGTACCCCTA CCCCCTGAGA CTGATGGCTA CGTTGCCCCC 
CTGACCTGCA GTCCCCAGCC TGAATACGTG AACCAGCCAG AGGTTTGGCC AAAGCCCCCA 
TCGCCCTTAG AAGGCCCTCT GCCTCCTTCT CGACCTGCCG GTGCCACTCT GGAAAGGCCC 
AAGACTCTGT CCCCCAAGAC TCTTTCCCCC GGCAAGAATG GGGTTGTCAA AGACGTTTTT 
GCCTTTGGGG GTGCTGTGGA GAACCCCGAG TACTTGGCAC CCCGGGGCAG GGCTGCCCCT 
CAGCCTCACC CTCCTCCAGC CTTCAGCCCA GCCTTTGACA ACCTCTATTA CTGGGACCAG 
GACACATCTG AGCGGGGCTC TCCACCCAGC ACCTTTGAAG GGACCCCTAC AGCAGAGAAC 
CCCGAATACC TGGGCCTGGA TGTGCCAGTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERBB2 ( XM_006940248.4 ) cDNA ORF clone, Felis catus(domestic cat) -> XP_006940310.2 Felis catus erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant X1, mRNA.

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CloneID	OFb64284
Clone ID Related Accession (Same CDS sequence)	XM_006940248.4
Accession Version	XM_006940248.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3693bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1512921600000
Organism	Felis catus(domestic cat)
Product	receptor tyrosine-protein kinase erbB-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_018736.3) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 12, 2017 this sequence version replaced XM_006940248.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Felis catus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGC GGCTCCCAGC CAGTCCCGAG ACCCACCTGG ACATGCTCCG CCACCTCTAC 
CAGGGCTGTC AAGTGGTACA GGGCAACCTG GAGCTCACCT ACCTGCATGC CAATGCCAGC 
CTCTCCTTCC TGCAGGATAT CCAGGAGGTG CAAGGCTATG TGCTCATTGC CCACAACCAA 
GTGAAACAGG TCCCACTGCA GAGGCTACGA ATCGTGCGAG GCACCCAGCT CTTTGAGGAC 
AACTACGCCC TGGCCGTGCT GGACAACGGA GACCCACTGG ACAGTGGCAC CCCTGCTACA 
GGGGCTGCCC TAGGAGGGCT GCGGGAGCTG CAGCTCCGAA GCCTCACAGA GATCCTGAAG 
GGAGGGGTCC TCATTCAGCG GAACCCGCAG CTCTGCCACC AGGACACGAT TCTGTGGAAG 
GACATCTTCC ACAAGAACAA CCAGCTGGCC CTCATGCTGA TAGACACCAA CCGCTCTCGG 
GCCTGCCAAC CCTGTTCTCC AGCTTGTAAA GACTCCCACT GCTGGGGAGC AAGTTCCGGG 
GACTGTCAGA GCTTGACTCG AACTGTCTGT GCTGGCGGCT GTGCCCGCTG CAAGGGCCCG 
CAGCCCACCG ACTGCTGCCA CGAGCAGTGT GCTGCTGGCT GCACGGGCCC CAAGCATTCT 
GACTGCCTGG CCTGCCTCCA CTTCAACCAC AGTGGCATCT GTGAGCTGCA CTGCCCAGCC 
CTGGTCACCT ACAACACGGA CACCTTCGAA TCCATGCCCA ACCCTGAGGG CCGTTATACC 
TTCGGTGCCA GCTGTGTGAC TGCCTGTCCC TACAACTACC TGTCTACGGA CGTGGGATCC 
TGCACCCTGG TCTGTCCCCT GAACAACCAA GAGGTGACAG CTGAGGATGG AACACAGCGG 
TGTGAGAAAT GCAGCAAGCC CTGTGCCCGA GTGTGCTACG GCCTAGGCAT GGAGCACCTG 
CGGGAGGCGA GGGCAGTCAC CAGTGCCAAC ATCCAAGAAT TTGTCGGCTG CAAGAAGATC 
TTTGGGAGCC TGGCGTTTCT GCCAGAGAGC TTTGAGGGGG ACCCAGCCTC CAACACTGCC 
CCCCTGCAGC CTGAGCAGCT CAGAGTGTTT GAGGCTCTGG AGGAGATTAC AGGTTACCTG 
TACATCTCAG CGTGGCCAGA CAGCTTGCCT AACCTCAGTG TCTTCCAGAA CCTCAGAGTG 
ATCCGGGGCC GAGTTCTGCA TGACGGTGCT TACTCGCTGA CCCTTCAAGG GCTGGGCATC 
AGCTGGCTGG GGCTGCGCTC GCTGCGGGAG CTGGGCAGTG GGCTGGCCCT CATCCACCGC 
AACTCCCGCC TCTGCTTCGT ACACACGGTG CCCTGGGACC AGCTCTTCCG GAACCCCCAC 
CAGGCCCTGC TCCACAGCGC CAACCGGCCA GAGGACGAGT GCGCGGGTGA GGGCCTGGCC 
TGCTATCCGC TGTGTGCCCA CGGGCACTGC TGGGGTCCGG GACCCACCCA GTGTGTCAAC 
TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC GTGGAGGAAT GCCGAGTATT GCAGGGGCTT 
CCCCGGGAGT ATGTGAAGGA TAGGTTCTGT CTGCCATGCC ACCCGGAGTG TCAGCCCCAG 
AATGGCTCAG TGACCTGCTT GGGCTCGGAA GCTGACCAGT GTGTGGCCTG TGCCCACTAC 
AAGGACCCTC CTTTCTGTGT GGCTCGCTGC CCCAGTGGGG TGAAACCTGA CCTCTCCTTC 
ATGCCCATCT GGAAGTTCGC AGATGAGGAG GGCACGTGCC AGCCATGCCC CATCAACTGC 
ACCCACTCCT GTGCGGACCT GGACGAGAAG GGCTGCCCCG CTGAGCAGAG AGCCAGCCCT 
GTGACGTCCA TCATTGCTGC TGTGGTGGGC ATTCTGCTGG TCGTGGTTGT GGGGCTGGTC 
CTTGGCATCC TAATCAAGCG AAGGCGGCAG AAGATCCGGA AGTACACGAT GCGGAGGCTG 
CTGCAGGAGA CGGAGCTGGT GGAGCCCCTG ACGCCTAGTG GAGCCATGCC CAACCAGGCT 
CAGATGCGAA TCCTGAAAGA AACAGAGCTG AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT 
TTTGGCACTG TCTACAAGGG CATCTGGATC CCTGATGGGG AAAATGTGAA AATCCCAGTG 
GCCATCAAAG TGTTGAGGGA AAATACATCT CCCAAAGCCA ACAAAGAAAT CTTGGACGAA 
GCGTATGTGA TGGCTGGCGT GGGCTCCCCA TATGTGTCTC GCCTTCTGGG CATCTGTCTG 
ACATCCACCG TGCAGTTGGT GACACAGCTT ATGCCTTATG GCTGCCTCTT AGACCATGTC 
CGAGAACACC GTGGGCGCCT AGGCTCCCAG GACCTGCTGA ACTGGTGTGT GCAGATTGCC 
AAGGGGATGA GCTACTTGGA GGATGTTCGG CTCGTGCACA GGGACCTGGC TGCCCGGAAC 
GTGCTGGTCA AGAGTCCCAA CCACGTCAAG ATTACAGATT TTGGGCTGGC TCGGCTGCTG 
GACATTGACG AGACAGAGTA CCATGCCGAT GGGGGCAAGG TGCCCATCAA GTGGATGGCG 
CTGGAGTCCA TTCTCCGCCG GCGGTTCACC CATCAGAGTG ACGTGTGGAG CTACGGTGTG 
ACTGTATGGG AACTGATGAC TTTTGGGGCC AAACCTTATG ATGGGATCCC AGCCCGGGAG 
ATTCCTGACC TGCTGGAGAA GGGGGAACGG CTGCCCCAGC CCCCCATCTG CACCATTGAT 
GTCTACATGA TCATGGTCAA ATGTTGGATG ATAGACTCTG AATGTCGGCC ACGTTTCCGG 
GAGCTGGTGG CCGAATTCTC CCGGATGGCC AGGGACCCCC AGCGCTTTGT GGTCATCCAG 
AATGAGGACT TGGGCCCAGC GAGTCCCCTG GACAGCACTT TCTACCGTTC ACTGCTGGAG 
GATGAGGACA TGGGAGACCT GGTGGATGCT GAGGAGTACC TGGTACCCCA GCAGGGTTTC 
TTCTGCCCAG ACCCTGCCCC AGGCGCCGGG GGCACAGCCC ACCGCAGACA CCGCAGCTCA 
TCCACCAGGA GTGGCGGTGG TGAGCTGACA CTGGGGCTGG AGCCCTCCGA GGAAGAGCCT 
CCCAAGTCTC CACTGGCACC CTCAGAAGGG GCTGGCTCTG ATGTGTTTGA TGGCGACTTG 
GGAATGGGGG CAGCCAAGGG GCTGCAGAGC CTTTCCCCAC AGGACCCCAG CCCTCTACAG 
CGGTACAGTG AGGATCCTAC CGTACCCCTA CCCCCTGAGA CTGATGGCTA CGTTGCCCCC 
CTGACCTGCA GTCCCCAGCC TGAATACGTG AACCAGCCAG AGGTTTGGCC AAAGCCCCCA 
TCGCCCTTAG AAGGCCCTCT GCCTCCTTCT CGACCTGCCG GTGCCACTCT GGAAAGGCCC 
AAGACTCTGT CCCCCAAGAC TCTTTCCCCC GGCAAGAATG GGGTTGTCAA AGACGTTTTT 
GCCTTTGGGG GTGCTGTGGA GAACCCCGAG TACTTGGCAC CCCGGGGCAG GGCTGCCCCT 
CAGCCTCACC CTCCTCCAGC CTTCAGCCCA GCCTTTGACA ACCTCTATTA CTGGGACCAG 
GACACATCTG AGCGGGGCTC TCCACCCAGC ACCTTTGAAG GGACCCCTAC AGCAGAGAAC 
CCCGAATACC TGGGCCTGGA TGTGCCAGTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006940310.2
CDS	43..3735
Translation	MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLHANASLSFLQDIQEVQGYVLIAHNQVKQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLDSGTPATGAALGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLALMLIDTNRSRACQPCSPACKDSHCWGASSGDCQSLTRTVCAGGCARCKGPQPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSANIQEFVGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLPNLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNSRLCFVHTVPWDQLFRNPHQALLHSANRPEDECAGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVKDRFCLPCHPECQPQNGSVTCLGSEADQCVACAHYKDPPFCVARCPSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDEKGCPAEQRASPVTSIIAAVVGILLVVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDEDMGDLVDAEEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEGAGSDVFDGDLGMGAAKGLQSLSPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYVNQPEVWPKPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGGAVENPEYLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDTSERGSPPSTFEGTPTAENPEYLGLDVPV

Target ORF information:

RefSeq Version	XM_006940248.4
Organism	Felis catus(domestic cat)
Definition	Felis catus erb-b2 receptor tyrosine kinase 2 (ERBB2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006940248.4

ORF Insert Sequence:

ATGAAGCTGC GGCTCCCAGC CAGTCCCGAG ACCCACCTGG ACATGCTCCG CCACCTCTAC 
CAGGGCTGTC AAGTGGTACA GGGCAACCTG GAGCTCACCT ACCTGCATGC CAATGCCAGC 
CTCTCCTTCC TGCAGGATAT CCAGGAGGTG CAAGGCTATG TGCTCATTGC CCACAACCAA 
GTGAAACAGG TCCCACTGCA GAGGCTACGA ATCGTGCGAG GCACCCAGCT CTTTGAGGAC 
AACTACGCCC TGGCCGTGCT GGACAACGGA GACCCACTGG ACAGTGGCAC CCCTGCTACA 
GGGGCTGCCC TAGGAGGGCT GCGGGAGCTG CAGCTCCGAA GCCTCACAGA GATCCTGAAG 
GGAGGGGTCC TCATTCAGCG GAACCCGCAG CTCTGCCACC AGGACACGAT TCTGTGGAAG 
GACATCTTCC ACAAGAACAA CCAGCTGGCC CTCATGCTGA TAGACACCAA CCGCTCTCGG 
GCCTGCCAAC CCTGTTCTCC AGCTTGTAAA GACTCCCACT GCTGGGGAGC AAGTTCCGGG 
GACTGTCAGA GCTTGACTCG AACTGTCTGT GCTGGCGGCT GTGCCCGCTG CAAGGGCCCG 
CAGCCCACCG ACTGCTGCCA CGAGCAGTGT GCTGCTGGCT GCACGGGCCC CAAGCATTCT 
GACTGCCTGG CCTGCCTCCA CTTCAACCAC AGTGGCATCT GTGAGCTGCA CTGCCCAGCC 
CTGGTCACCT ACAACACGGA CACCTTCGAA TCCATGCCCA ACCCTGAGGG CCGTTATACC 
TTCGGTGCCA GCTGTGTGAC TGCCTGTCCC TACAACTACC TGTCTACGGA CGTGGGATCC 
TGCACCCTGG TCTGTCCCCT GAACAACCAA GAGGTGACAG CTGAGGATGG AACACAGCGG 
TGTGAGAAAT GCAGCAAGCC CTGTGCCCGA GTGTGCTACG GCCTAGGCAT GGAGCACCTG 
CGGGAGGCGA GGGCAGTCAC CAGTGCCAAC ATCCAAGAAT TTGTCGGCTG CAAGAAGATC 
TTTGGGAGCC TGGCGTTTCT GCCAGAGAGC TTTGAGGGGG ACCCAGCCTC CAACACTGCC 
CCCCTGCAGC CTGAGCAGCT CAGAGTGTTT GAGGCTCTGG AGGAGATTAC AGGTTACCTG 
TACATCTCAG CGTGGCCAGA CAGCTTGCCT AACCTCAGTG TCTTCCAGAA CCTCAGAGTG 
ATCCGGGGCC GAGTTCTGCA TGACGGTGCT TACTCGCTGA CCCTTCAAGG GCTGGGCATC 
AGCTGGCTGG GGCTGCGCTC GCTGCGGGAG CTGGGCAGTG GGCTGGCCCT CATCCACCGC 
AACTCCCGCC TCTGCTTCGT ACACACGGTG CCCTGGGACC AGCTCTTCCG GAACCCCCAC 
CAGGCCCTGC TCCACAGCGC CAACCGGCCA GAGGACGAGT GCGCGGGTGA GGGCCTGGCC 
TGCTATCCGC TGTGTGCCCA CGGGCACTGC TGGGGTCCGG GACCCACCCA GTGTGTCAAC 
TGCAGCCAGT TCCTTCGGGG CCAGGAGTGC GTGGAGGAAT GCCGAGTATT GCAGGGGCTT 
CCCCGGGAGT ATGTGAAGGA TAGGTTCTGT CTGCCATGCC ACCCGGAGTG TCAGCCCCAG 
AATGGCTCAG TGACCTGCTT GGGCTCGGAA GCTGACCAGT GTGTGGCCTG TGCCCACTAC 
AAGGACCCTC CTTTCTGTGT GGCTCGCTGC CCCAGTGGGG TGAAACCTGA CCTCTCCTTC 
ATGCCCATCT GGAAGTTCGC AGATGAGGAG GGCACGTGCC AGCCATGCCC CATCAACTGC 
ACCCACTCCT GTGCGGACCT GGACGAGAAG GGCTGCCCCG CTGAGCAGAG AGCCAGCCCT 
GTGACGTCCA TCATTGCTGC TGTGGTGGGC ATTCTGCTGG TCGTGGTTGT GGGGCTGGTC 
CTTGGCATCC TAATCAAGCG AAGGCGGCAG AAGATCCGGA AGTACACGAT GCGGAGGCTG 
CTGCAGGAGA CGGAGCTGGT GGAGCCCCTG ACGCCTAGTG GAGCCATGCC CAACCAGGCT 
CAGATGCGAA TCCTGAAAGA AACAGAGCTG AGGAAGGTGA AGGTGCTTGG ATCCGGAGCT 
TTTGGCACTG TCTACAAGGG CATCTGGATC CCTGATGGGG AAAATGTGAA AATCCCAGTG 
GCCATCAAAG TGTTGAGGGA AAATACATCT CCCAAAGCCA ACAAAGAAAT CTTGGACGAA 
GCGTATGTGA TGGCTGGCGT GGGCTCCCCA TATGTGTCTC GCCTTCTGGG CATCTGTCTG 
ACATCCACCG TGCAGTTGGT GACACAGCTT ATGCCTTATG GCTGCCTCTT AGACCATGTC 
CGAGAACACC GTGGGCGCCT AGGCTCCCAG GACCTGCTGA ACTGGTGTGT GCAGATTGCC 
AAGGGGATGA GCTACTTGGA GGATGTTCGG CTCGTGCACA GGGACCTGGC TGCCCGGAAC 
GTGCTGGTCA AGAGTCCCAA CCACGTCAAG ATTACAGATT TTGGGCTGGC TCGGCTGCTG 
GACATTGACG AGACAGAGTA CCATGCCGAT GGGGGCAAGG TGCCCATCAA GTGGATGGCG 
CTGGAGTCCA TTCTCCGCCG GCGGTTCACC CATCAGAGTG ACGTGTGGAG CTACGGTGTG 
ACTGTATGGG AACTGATGAC TTTTGGGGCC AAACCTTATG ATGGGATCCC AGCCCGGGAG 
ATTCCTGACC TGCTGGAGAA GGGGGAACGG CTGCCCCAGC CCCCCATCTG CACCATTGAT 
GTCTACATGA TCATGGTCAA ATGTTGGATG ATAGACTCTG AATGTCGGCC ACGTTTCCGG 
GAGCTGGTGG CCGAATTCTC CCGGATGGCC AGGGACCCCC AGCGCTTTGT GGTCATCCAG 
AATGAGGACT TGGGCCCAGC GAGTCCCCTG GACAGCACTT TCTACCGTTC ACTGCTGGAG 
GATGAGGACA TGGGAGACCT GGTGGATGCT GAGGAGTACC TGGTACCCCA GCAGGGTTTC 
TTCTGCCCAG ACCCTGCCCC AGGCGCCGGG GGCACAGCCC ACCGCAGACA CCGCAGCTCA 
TCCACCAGGA GTGGCGGTGG TGAGCTGACA CTGGGGCTGG AGCCCTCCGA GGAAGAGCCT 
CCCAAGTCTC CACTGGCACC CTCAGAAGGG GCTGGCTCTG ATGTGTTTGA TGGCGACTTG 
GGAATGGGGG CAGCCAAGGG GCTGCAGAGC CTTTCCCCAC AGGACCCCAG CCCTCTACAG 
CGGTACAGTG AGGATCCTAC CGTACCCCTA CCCCCTGAGA CTGATGGCTA CGTTGCCCCC 
CTGACCTGCA GTCCCCAGCC TGAATACGTG AACCAGCCAG AGGTTTGGCC AAAGCCCCCA 
TCGCCCTTAG AAGGCCCTCT GCCTCCTTCT CGACCTGCCG GTGCCACTCT GGAAAGGCCC 
AAGACTCTGT CCCCCAAGAC TCTTTCCCCC GGCAAGAATG GGGTTGTCAA AGACGTTTTT 
GCCTTTGGGG GTGCTGTGGA GAACCCCGAG TACTTGGCAC CCCGGGGCAG GGCTGCCCCT 
CAGCCTCACC CTCCTCCAGC CTTCAGCCCA GCCTTTGACA ACCTCTATTA CTGGGACCAG 
GACACATCTG AGCGGGGCTC TCCACCCAGC ACCTTTGAAG GGACCCCTAC AGCAGAGAAC 
CCCGAATACC TGGGCCTGGA TGTGCCAGTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status.
Oncotarget7(14)17314-26(2016 Apr)
Soares M,Ribeiro R,Najmudin S,Gameiro A,Rodrigues R,Cardoso F,Ferreira F

Changes in c-erbB-2 Immunoexpression in Feline Endometrial Adenocarcinomas.
Reproduction in domestic animals = Zuchthygiene51(1)33-9(2016 Feb)
Saraiva AL,Payan-Carreira R,Gärtner F,Faria F,Lourenço LM,Pires MA

Molecular phenotype of primary mammary tumours and distant metastases in female dogs and cats.
Journal of comparative pathology150(2-3)194-7(2014 Feb-Apr)
Beha G,Muscatello LV,Brunetti B,Asproni P,Millanta F,Poli A,Benazzi C,Sarli G

Sequence variants and haplotype analysis of cat ERBB2 gene: a survey on spontaneous cat mammary neoplastic and non-neoplastic lesions.
International journal of molecular sciences13(3)2783-800(2012)
Santos S,Bastos E,Baptista CS,Sá D,Caloustian C,Guedes-Pinto H,Gärtner F,Gut IG,Chaves R

Spontaneous feline mammary carcinoma is a model of HER2 overexpressing poor prognosis human breast cancer.
Cancer research65(3)907-12(2005 Feb)
De Maria R,Olivero M,Iussich S,Nakaichi M,Murata T,Biolatti B,Di Renzo MF

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ERBB2 cDNA ORF clone, Felis catus(domestic cat)

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Target ORF information:

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ORF Insert Sequence:

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ORF Insert Sequence:

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