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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


NOTCH1 Intracellular Domain Regulates Transcription NOTCH2 Activation and Transmission of Signal to the Nucleus
Signaling by NOTCH3 Peptide ligand-binding receptors
Chemokine receptors bind chemokines Vasopressin-like receptors
Orexin and neuropeptides FF and QRFP bind to their respective receptors Hormone ligand-binding receptors
Calcitonin-like ligand receptors G alpha (s) signalling events
G alpha (i) signalling events G alpha (12/13) signalling events
phospho-PLA2 pathway EGFR Transactivation by Gastrin
Disassembly of the destruction complex and recruitment of AXIN to the membrane Degradation of AXIN
Asymmetric localization of PCP proteins Ca2+ pathway
Signaling by Hippo Signaling by Activin
Antagonism of Activin by Follistatin Visual phototransduction
The phototransduction cascade Signaling by Hedgehog
Hedgehog ligand biogenesis Degradation of GLI2 by the proteasome
RNA Polymerase I Promoter Clearance RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
Cleavage of Growing Transcript in the Termination Region mRNA Splicing
Transport of Mature mRNAs Derived from Intronless Transcripts Processing of Capped Intronless Pre-mRNA
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs Deadenylation of mRNA
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Small interfering RNA (siRNA) biogenesis
Post-transcriptional silencing by small RNAs Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression Cell Cycle Checkpoints
Interleukin-10 signaling TBC/RABGAPs
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Regulation of TLR by endogenous ligand Deubiquitination
UCH proteinases SUMOylation of RNA binding proteins
Retinoid metabolism disease events Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3)
Activation of anterior HOX genes in hindbrain development during early embryogenesis Complex I biogenesis
Selenoamino acid metabolism tRNA modification in the nucleus and cytosol
TNFR1-mediated ceramide production Homology Directed Repair
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) Homologous DNA Pairing and Strand Exchange
Resolution of D-loop Structures through Holliday Junction Intermediates Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Nonhomologous End-Joining (NHEJ) Dual incision in TC-NER
MAP3K8 (TPL2)-dependent MAPK1/3 activation SLC transporter disorders
Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) Defective TRP may confer susceptibility towards thyroid papillary carcinoma (TPC)
Defective pro-SFTPB causes pulmonary surfactant metabolism dysfunction 1 (SMDP1) and respiratory distress syndrome (RDS) Mitophagy
Surfactant metabolism ERBB2 Regulates Cell Motility
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases PTK6 promotes HIF1A stabilization
Signaling by MST1 Defective LFNG causes SCDO3
Defective B3GALTL causes Peters-plus syndrome (PpS) Glycerophospholipid catabolism
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Regulation of TP53 Activity rRNA modification in the nucleus and cytosol
Neurodegenerative Diseases PI5P Regulates TP53 Acetylation
MET promotes cell motility MET receptor recycling
Negative regulation of MET activity Protein ubiquitination
Digestion of dietary carbohydrate Gluconeogenesis
Lysosomal glycogen catabolism Hyaluronan biosynthesis and export
Keratan sulfate/keratin metabolism HS-GAG degradation
Chondroitin sulfate/dermatan sulfate metabolism Chondroitin sulfate biosynthesis
Synthesis of IP3 and IP4 in the cytosol Synthesis of IPs in the ER lumen
Synthesis of IP2, IP, and Ins in the cytosol Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
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