ORF » Species Summary » Homo sapiens » Reactome

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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


Beta oxidation of myristoyl-CoA to lauroyl-CoA Beta oxidation of butanoyl-CoA to acetyl-CoA
PPARA activates gene expression Bile acid and bile salt metabolism
Synthesis of bile acids and bile salts Recycling of bile acids and salts
Pregnenolone biosynthesis Phospholipid metabolism
POLB-Dependent Long Patch Base Excision Repair PCNA-Dependent Long Patch Base Excision Repair
DNA Damage Bypass Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
Translesion synthesis by POLI DNA Damage Reversal
Reversal of alkylation damage by DNA dioxygenases Cellular responses to stress
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Cellular Senescence
PKMTs methylate histone lysines TAK1 activates NFkB by phosphorylation and activation of IKKs complex
activated TAK1 mediates p38 MAPK activation MAPK targets/ Nuclear events mediated by MAP kinases
ERK/MAPK targets Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
MyD88 dependent cascade initiated on endosome Complement cascade
Ficolins bind to repetitive carbohydrate structures on the target cell surface TRAF3-dependent IRF activation pathway
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Regulation by TREX1
Fcgamma receptor (FCGR) dependent phagocytosis DAP12 signaling
RAF/MAP kinase cascade Regulation of RAS by GAPs
CaM pathway Fc epsilon receptor (FCERI) signaling
FCERI mediated Ca+2 mobilization Dectin-1 mediated noncanonical NF-kB signaling
CLEC7A/inflammasome pathway Interferon alpha/beta signaling
Regulation of IFNG signaling Interleukin-1 processing
TNFs bind their physiological receptors Reduction of cytosolic Ca++ levels
Platelet Adhesion to exposed collagen Thrombin signalling through proteinase activated receptors (PARs)
GPVI-mediated activation cascade Dissolution of Fibrin Clot
Factors involved in megakaryocyte development and platelet production GRB2 events in EGFR signaling
SHC1 events in EGFR signaling SHC-mediated cascade:FGFR1
FGFR2 ligand binding and activation SHC-mediated cascade:FGFR2
PI-3K cascade:FGFR2 PI-3K cascade:FGFR3
Signaling by FGFR4 Downstream signaling of activated FGFR4
Insulin receptor signalling cascade NFG and proNGF binds to p75NTR
Cell death signalling via NRAGE, NRIF and NADE NRIF signals cell death from the nucleus
p75NTR recruits signalling complexes Axonal growth stimulation
NGF-independant TRKA activation Signalling to ERKs
Signalling to RAS p38MAPK events
Frs2-mediated activation Retrograde neurotrophin signalling
Signaling by VEGF Glycerophospholipid biosynthesis
Synthesis of PI Synthesis of PIPs at the Golgi membrane
alpha-linolenic acid (ALA) metabolism Arachidonic acid metabolism
Synthesis of 15-eicosatetraenoic acid derivatives Synthesis of Lipoxins (LX)
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) Adrenaline,noradrenaline inhibits insulin secretion
AMPK inhibits chREBP transcriptional activation activity NOSIP mediated eNOS trafficking
Pyruvate metabolism Regulation of pyruvate dehydrogenase (PDH) complex
Mitochondrial Uncoupling Proteins Purine ribonucleoside monophosphate biosynthesis
Metabolism of water-soluble vitamins and cofactors Vitamin C (ascorbate) metabolism
Vitamin B2 (riboflavin) metabolism Coenzyme A biosynthesis
Tryptophan catabolism Creatine metabolism
Agmatine biosynthesis Cysteine formation from homocysteine
Heme degradation Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
Eicosanoids Glucuronidation
Glutathione conjugation Conjugation of salicylate with glycine
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