Gene Symbol | RLN3 |
Entrez Gene ID | 503836 |
Full Name | relaxin 3 |
Synonyms | insl7 |
Gene Type | protein-coding |
Organism | Sus scrofa(Pig) |
ORF » Species Summary » Sus scrofa » RLN3 cDNA ORF clone
Gene Symbol | RLN3 |
Entrez Gene ID | 503836 |
Full Name | relaxin 3 |
Synonyms | insl7 |
Gene Type | protein-coding |
Organism | Sus scrofa(Pig) |
mRNA | Protein | Name |
---|---|---|
XM_013994666.2 | XP_013850120.1 | relaxin-3 isoform X2 |
XM_005661236.2 | XP_005661293.1 | relaxin-3 isoform X1 |
XM_005661236.3 | XP_005661293.1 | relaxin-3 isoform X1 |
XM_021081988.1 | XP_020937647.1 | relaxin-3 isoform X1 |
NM_001045679.1 | NP_001039144.1 | relaxin-3 precursor |
XM_021081995.1 | XP_020937654.1 | relaxin-3 isoform X2 |
XM_013994666.1 | XP_013850120.1 | relaxin-3 isoform X2 |
XM_013994667.1 | XP_013850121.1 | relaxin-3 isoform X2 |
XM_013994668.1 | XP_013850122.1 | relaxin-3 isoform X1 |
Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135.
Liu C, Eriste E, Sutton S, Chen J, Roland B, Kuei C, Farmer N, Jörnvall H, Sillard R, Lovenberg TW
The Journal of biological chemistry278(50)50754-64(2003 Dec)
Production of recombinant human relaxin 3 in AtT20 cells.
Kizawa H, Nishi K, Ishibashi Y, Harada M, Asano T, Ito Y, Suzuki N, Hinuma S, Fujisawa Y, Onda H, Nishimura O, Fujino M
Regulatory peptides113(1-3)79-84(2003 May)
H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.
Sudo S, Kumagai J, Nishi S, Layfield S, Ferraro T, Bathgate RA, Hsueh AJ
The Journal of biological chemistry278(10)7855-62(2003 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following RLN3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RLN3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe00242 | |
Clone ID Related Accession (Same CDS sequence) | XM_013994666.2 , NM_001045679.1 , XM_021081995.1 , XM_013994666.1 , XM_013994667.1 | |
Accession Version | NM_001045679.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1571414400000 | |
Organism | Sus scrofa(pig) | |
Product | relaxin-3 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB076661.2. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1876846, SAMEA2041641 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001039144.1 |
CDS | 1..423 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe00242 | |
Clone ID Related Accession (Same CDS sequence) | XM_013994666.2 , NM_001045679.1 , XM_021081995.1 , XM_013994666.1 , XM_013994667.1 | |
Accession Version | XM_013994666.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1494518400000 | |
Organism | Sus scrofa(pig) | |
Product | relaxin-3 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010444.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 13, 2017 this sequence version replaced XM_013994666.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013850120.1 |
CDS | 338..760 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe00242 | |
Clone ID Related Accession (Same CDS sequence) | XM_013994666.2 , NM_001045679.1 , XM_021081995.1 , XM_013994666.1 , XM_013994667.1 | |
Accession Version | XM_021081995.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1494518400000 | |
Organism | Sus scrofa(pig) | |
Product | relaxin-3 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010444.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_020937654.1 |
CDS | 393..815 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe00242 | |
Clone ID Related Accession (Same CDS sequence) | XM_013994666.2 , NM_001045679.1 , XM_021081995.1 , XM_013994666.1 , XM_013994667.1 | |
Accession Version | XM_013994666.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | relaxin-3 isoform X2 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003609603.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013850120.1 |
CDS | 338..760 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe00242 | |
Clone ID Related Accession (Same CDS sequence) | XM_013994666.2 , NM_001045679.1 , XM_021081995.1 , XM_013994666.1 , XM_013994667.1 | |
Accession Version | XM_013994667.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 423bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | relaxin-3 isoform X2 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003609603.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013850121.1 |
CDS | 388..810 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCAAAC GTCCACTGCT GCTGCTGCTG CTGGCCGTAT GGGTGCTGGC TGGGGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe04983 | |
Clone ID Related Accession (Same CDS sequence) | XM_005661236.2 , XM_005661236.3 , XM_021081988.1 , XM_013994668.1 | |
Accession Version | XM_005661236.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | relaxin-3 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003609603.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005661236.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTGGA AACTTGTCAC AAAGGCAGAT CCTCAGACAC TCTGCAGTCA GAGCCCAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005661293.1 |
CDS | 369..872 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCTGGA AACTTGTCAC AAAGGCAGAT CCTCAGACAC TCTGCAGTCA GAGCCCAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe04983 | |
Clone ID Related Accession (Same CDS sequence) | XM_005661236.2 , XM_005661236.3 , XM_021081988.1 , XM_013994668.1 | |
Accession Version | XM_005661236.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1494518400000 | |
Organism | Sus scrofa(pig) | |
Product | relaxin-3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010444.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 13, 2017 this sequence version replaced XM_005661236.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTGGA AACTTGTCAC AAAGGCAGAT CCTCAGACAC TCTGCAGTCA GAGCCCAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005661293.1 |
CDS | 391..894 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCCTGGA AACTTGTCAC AAAGGCAGAT CCTCAGACAC TCTGCAGTCA GAGCCCAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe04983 | |
Clone ID Related Accession (Same CDS sequence) | XM_005661236.2 , XM_005661236.3 , XM_021081988.1 , XM_013994668.1 | |
Accession Version | XM_021081988.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1494518400000 | |
Organism | Sus scrofa(pig) | |
Product | relaxin-3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010444.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTGGA AACTTGTCAC AAAGGCAGAT CCTCAGACAC TCTGCAGTCA GAGCCCAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_020937647.1 |
CDS | 362..865 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTGGA AACTTGTCAC AAAGGCAGAT CCTCAGACAC TCTGCAGTCA GAGCCCAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe04983 | |
Clone ID Related Accession (Same CDS sequence) | XM_005661236.2 , XM_005661236.3 , XM_021081988.1 , XM_013994668.1 | |
Accession Version | XM_013994668.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | relaxin-3 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003609603.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTGGA AACTTGTCAC AAAGGCAGAT CCTCAGACAC TCTGCAGTCA GAGCCCAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_013850122.1 |
CDS | 190..693 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCCTGGA AACTTGTCAC AAAGGCAGAT CCTCAGACAC TCTGCAGTCA GAGCCCAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135. |
Production of recombinant human relaxin 3 in AtT20 cells. |
H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2. |