Gene Symbol | EDNRB |
Entrez Gene ID | 414911 |
Full Name | endothelin receptor type B |
Synonyms | ETB |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
ORF » Species Summary » Sus scrofa » EDNRB cDNA ORF clone
Gene Symbol | EDNRB |
Entrez Gene ID | 414911 |
Full Name | endothelin receptor type B |
Synonyms | ETB |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
mRNA | Protein | Name |
---|---|---|
XM_005668476.2 | XP_005668533.1 | endothelin B receptor isoform X1 |
NM_001038002.1 | NP_001033091.1 | endothelin receptor type B precursor |
XM_005668476.3 | XP_005668533.1 | endothelin B receptor isoform X1 |
Pulmonary vasoconstrictor influence of endothelin in exercising swine depends critically on phosphodiesterase 5 activity.
Zhou Z, de Beer VJ, de Wijs-Meijler D, Bender SB, Hoekstra M, Laughlin MH, Duncker DJ, Merkus D
American journal of physiology. Lung cellular and molecular physiology306(5)L442-52(2014 Mar)
Endothelin ET(B) receptors are involved in the relaxation to the pig urinary bladder neck.
Arteaga JL, Orensanz LM, Martínez MP, Barahona MV, Martínez-Sáenz A, Fernandes VS, Bustamante S, Carballido J, Benedito S, García-Sacristán A, Prieto D, Hernández M
Neurourology and urodynamics31(5)688-94(2012 Jun)
Dual endothelin receptor blockade with tezosentan markedly attenuates hypoxia-induced pulmonary vasoconstriction in a porcine model.
Hedelin P, Kylhammar D, Rådegran G
Acta physiologica (Oxford, England)204(3)419-34(2012 Mar)
Activation of ETB receptors regulates the abundance of ET-1 mRNA in vascular endothelial cells.
Farhat N, Matouk CC, Mamarbachi AM, Marsden PA, Allen BG, Thorin E
British journal of pharmacology153(7)1420-31(2008 Apr)
PKC and MAPK signalling pathways regulate vascular endothelin receptor expression.
Nilsson D, Wackenfors A, Gustafsson L, Ugander M, Ingemansson R, Edvinsson L, Malmsjö M
European journal of pharmacology580(1-2)190-200(2008 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following EDNRB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EDNRB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe00820 | |
Clone ID Related Accession (Same CDS sequence) | XM_005668476.2 , NM_001038002.1 , XM_005668476.3 | |
Accession Version | NM_001038002.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1332bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1577116800000 | |
Organism | Sus scrofa(pig) | |
Product | endothelin receptor type B precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB209953.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209953.1, AK231838.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1487420, SAMEA1487433 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGCAGCCGC TGCGCAGCCT ATGCGGACGC GCCCTGGTGG CGCTGATCTT TGCCTGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001033091.1 |
CDS | 155..1486 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCAGCCGC TGCGCAGCCT ATGCGGACGC GCCCTGGTGG CGCTGATCTT TGCCTGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe00820 | |
Clone ID Related Accession (Same CDS sequence) | XM_005668476.2 , NM_001038002.1 , XM_005668476.3 | |
Accession Version | XM_005668476.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1332bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1441814400000 | |
Organism | Sus scrofa(Pig) | |
Product | endothelin B receptor isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003611418.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 11, 2015 this sequence version replaced XM_005668476.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAGCCGC TGCGCAGCCT ATGCGGACGC GCCCTGGTGG CGCTGATCTT TGCCTGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005668533.1 |
CDS | 260..1591 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCAGCCGC TGCGCAGCCT ATGCGGACGC GCCCTGGTGG CGCTGATCTT TGCCTGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe00820 | |
Clone ID Related Accession (Same CDS sequence) | XM_005668476.2 , NM_001038002.1 , XM_005668476.3 | |
Accession Version | XM_005668476.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1332bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1494518400000 | |
Organism | Sus scrofa(pig) | |
Product | endothelin B receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010453.5) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 13, 2017 this sequence version replaced XM_005668476.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAGCCGC TGCGCAGCCT ATGCGGACGC GCCCTGGTGG CGCTGATCTT TGCCTGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005668533.1 |
CDS | 406..1737 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCAGCCGC TGCGCAGCCT ATGCGGACGC GCCCTGGTGG CGCTGATCTT TGCCTGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Pulmonary vasoconstrictor influence of endothelin in exercising swine depends critically on phosphodiesterase 5 activity. |
Endothelin ET(B) receptors are involved in the relaxation to the pig urinary bladder neck. |
Dual endothelin receptor blockade with tezosentan markedly attenuates hypoxia-induced pulmonary vasoconstriction in a porcine model. |
Activation of ETB receptors regulates the abundance of ET-1 mRNA in vascular endothelial cells. |
PKC and MAPK signalling pathways regulate vascular endothelin receptor expression. |