Gene Symbol | Nkx6-1 |
Entrez Gene ID | 101826537 |
Full Name | NK6 homeobox 1 |
Synonyms | NKX6A,NKx6.1 |
Gene Type | protein-coding |
Organism | Mesocricetus auratus(golden hamster) |
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ORF » Species Summary » Mesocricetus auratus » Nkx6-1 cDNA ORF clone
Gene Symbol | Nkx6-1 |
Entrez Gene ID | 101826537 |
Full Name | NK6 homeobox 1 |
Synonyms | NKX6A,NKx6.1 |
Gene Type | protein-coding |
Organism | Mesocricetus auratus(golden hamster) |
mRNA | Protein | Name |
---|---|---|
NM_001281696.1 | NP_001268625.1 | homeobox protein Nkx-6.1 |
De novo assembly, annotation, and characterization of the whole brain transcriptome of male and female Syrian hamsters.
McCann KE, Sinkiewicz DM, Norvelle A, Huhman KL
Scientific reports740472(2017 01)
Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1.
Schisler JC, Fueger PT, Babu DA, Hohmeier HE, Tessem JS, Lu D, Becker TC, Naziruddin B, Levy M, Mirmira RG, Newgard CB
Molecular and cellular biology28(10)3465-76(2008 May)
The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter.
Taylor DG, Babu D, Mirmira RG
Biochemistry44(33)11269-78(2005 Aug)
The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1.
Iype T, Taylor DG, Ziesmann SM, Garmey JC, Watada H, Mirmira RG
Molecular endocrinology (Baltimore, Md.)18(6)1363-75(2004 Jun)
Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains.
Mirmira RG, Watada H, German MS
The Journal of biological chemistry275(19)14743-51(2000 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Nkx6-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nkx6-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMe12601 | |
Clone ID Related Accession (Same CDS sequence) | NM_001281696.1 | |
Accession Version | NM_001281696.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1568908800000 | |
Organism | Mesocricetus auratus(golden hamster) | |
Product | homeobox protein Nkx-6.1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X81409.1. On Aug 1, 2013 this sequence version replaced XM_005076362.1. ##Evidence-Data-START## Transcript exon combination :: X81409.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN01831924, SAMN01831926 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTTAGCTG TGGGGGCGAT GGAGGGCCCC CGGCAGAGCG CGTTTCTGCT CAGCAGCCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001268625.1 |
CDS | 23..1117 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGTTAGCTG TGGGGGCGAT GGAGGGCCCC CGGCAGAGCG CGTTTCTGCT CAGCAGCCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
De novo assembly, annotation, and characterization of the whole brain transcriptome of male and female Syrian hamsters. |
Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1. |
The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter. |
The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. |
Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains. |