IL10 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL10
Entrez Gene ID	694931
Full Name	interleukin 10
Gene Type	protein-coding
Organism	Macaca mulatta(Rhesus monkey)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001044727.1	NP_001038192.1	interleukin-10 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	IL10	NP_000563.1
Canis lupus familiaris (dog)	IL10	NP_001003077.1
Mus musculus (house mouse)	Il10	NP_034678.1
Rattus norvegicus (Norway rat)	Il10	NP_036986.2
Xenopus tropicalis (tropical clawed frog)	il10	NP_001165400.1
Macaca mulatta (Rhesus monkey)	IL10	NP_001038192.1
Bos taurus (cattle)	IL10	NP_776513.1
Gallus gallus (chicken)	IL10	NP_001004414.2
Pan troglodytes (chimpanzee)	IL10	NP_001129092.2
Danio rerio (zebrafish)	il10	NP_001018621.2

Gene Ontology
Bibliography

Related articles in PubMed

The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection.
Mooney JP, Butler BP, Lokken KL, Xavier MN, Chau JY, Schaltenberg N, Dandekar S, George MD, Santos RL, Luckhart S, Tsolis RM
Mucosal immunology7(6)1302-11(2014 Nov)

Lack of interleukin-10-mediated anti-inflammatory signals and upregulated interferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection.
Pan D, Kenway-Lynch CS, Lala W, Veazey RS, Lackner AA, Das A, Pahar B
Journal of virology88(22)13015-28(2014 Nov)

Interleukin-10 prevents epithelial cell apoptosis by regulating IFNγ and TNFα expression in rhesus macaque colon explants.
Pan D, Das A, Lala W, Kenway-Lynch CS, Liu DX, Veazey RS, Pahar B
Cytokine64(1)30-4(2013 Oct)

Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Yan G, Zhang G, Fang X, Zhang Y, Li C, Ling F, Cooper DN, Li Q, Li Y, van Gool AJ, Du H, Chen J, Chen R, Zhang P, Huang Z, Thompson JR, Meng Y, Bai Y, Wang J, Zhuo M, Wang T, Huang Y, Wei L, Li J, Wang Z, Hu H, Yang P, Le L, Stenson PD, Li B, Liu X, Ball EV, An N, Huang Q, Zhang Y, Fan W, Zhang X, Li Y, Wang W, Katze MG, Su B, Nielsen R, Yang H, Wang J, Wang X, Wang J
Nature biotechnology29(11)1019-23(2011 Oct)

Polymorphisms in eight host genes associated with control of HIV replication do not mediate elite control of viral replication in SIV-infected Indian rhesus macaques.
Weiler A, May GE, Qi Y, Wilson N, Watkins DI
Immunogenetics58(12)1003-9(2006 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following IL10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMb04754	NM_001044727.1 Latest version!	Macaca mulatta interleukin 10 (IL10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL10 ( NM_001044727.1 ) cDNA ORF clone, Macaca mulatta(Rhesus monkey) -> NP_001038192.1 Macaca mulatta interleukin 10 (IL10), mRNA.

Price & Availability↑

CloneID	OMb04754
Clone ID Related Accession (Same CDS sequence)	NM_001044727.1
Accession Version	NM_001044727.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1577203200000
Organism	Macaca mulatta(Rhesus monkey)
Product	interleukin-10 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from L26029.1. On Aug 31, 2006 this sequence version replaced XM_001085083.1. ##Evidence-Data-START## Transcript exon combination :: L26029.1, DQ890039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4688325, SAMEA4688338 [ECO:0000348] ##Evidence-Data-END##

ATGCACAGCT CAGCACTGCT CTGTTGCCTA GTCCTCCTGA CTGGGGTGAG GGCCAGCCCA 
GGCCAGGGCA CCCAGTCTGA GAACAGCTGC ACCCGCTTCC CAGGCAACCT GCCTCACATG 
CTTCGAGACC TCCGAGATGC CTTCAGCAGA GTGAAGACTT TCTTTCAAAT GAAGGATCAG 
CTGGACAACA TATTGTTAAA GGAGTCCTTG CTGGAGGACT TTAAGGGTTA CCTGGGTTGC 
CAAGCCTTGT CTGAGATGAT CCAGTTTTAC CTGGAGGAGG TGATGCCCCA AGCTGAGAAC 
CACGACCCAG ACATCAAGGA GCATGTGAAC TCCCTGGGGG AGAATCTGAA GACCCTCAGG 
CTGAGGCTGC GGCGCTGTCA TCGATTTCTT CCCTGTGAAA ACAAGAGCAA GGCCGTGGAG 
CAGGTGAAGA ATGCCTTTAG TAAGCTCCAA GAGAAAGGCG TCTACAAAGC CATGAGTGAG 
TTTGACATCT TCATCAACTA CATAGAAGCC TACATGACAA TGAAGATACA AAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001038192.1
CDS	8..544
Translation	MHSSALLCCLVLLTGVRASPGQGTQSENSCTRFPGNLPHMLRDLRDAFSRVKTFFQMKDQLDNILLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENHDPDIKEHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFSKLQEKGVYKAMSEFDIFINYIEAYMTMKIQN

Target ORF information:

RefSeq Version	NM_001044727.1
Organism	Macaca mulatta(Rhesus monkey)
Definition	Macaca mulatta interleukin 10 (IL10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001044727.1

ORF Insert Sequence:

ATGCACAGCT CAGCACTGCT CTGTTGCCTA GTCCTCCTGA CTGGGGTGAG GGCCAGCCCA 
GGCCAGGGCA CCCAGTCTGA GAACAGCTGC ACCCGCTTCC CAGGCAACCT GCCTCACATG 
CTTCGAGACC TCCGAGATGC CTTCAGCAGA GTGAAGACTT TCTTTCAAAT GAAGGATCAG 
CTGGACAACA TATTGTTAAA GGAGTCCTTG CTGGAGGACT TTAAGGGTTA CCTGGGTTGC 
CAAGCCTTGT CTGAGATGAT CCAGTTTTAC CTGGAGGAGG TGATGCCCCA AGCTGAGAAC 
CACGACCCAG ACATCAAGGA GCATGTGAAC TCCCTGGGGG AGAATCTGAA GACCCTCAGG 
CTGAGGCTGC GGCGCTGTCA TCGATTTCTT CCCTGTGAAA ACAAGAGCAA GGCCGTGGAG 
CAGGTGAAGA ATGCCTTTAG TAAGCTCCAA GAGAAAGGCG TCTACAAAGC CATGAGTGAG 
TTTGACATCT TCATCAACTA CATAGAAGCC TACATGACAA TGAAGATACA AAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection.
Mucosal immunology7(6)1302-11(2014 Nov)
Mooney JP,Butler BP,Lokken KL,Xavier MN,Chau JY,Schaltenberg N,Dandekar S,George MD,Santos RL,Luckhart S,Tsolis RM

Lack of interleukin-10-mediated anti-inflammatory signals and upregulated interferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection.
Journal of virology88(22)13015-28(2014 Nov)
Pan D,Kenway-Lynch CS,Lala W,Veazey RS,Lackner AA,Das A,Pahar B

Interleukin-10 prevents epithelial cell apoptosis by regulating IFNγ and TNFα expression in rhesus macaque colon explants.
Cytokine64(1)30-4(2013 Oct)
Pan D,Das A,Lala W,Kenway-Lynch CS,Liu DX,Veazey RS,Pahar B

Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques.
Nature biotechnology29(11)1019-23(2011 Oct)
Yan G,Zhang G,Fang X,Zhang Y,Li C,Ling F,Cooper DN,Li Q,Li Y,van Gool AJ,Du H,Chen J,Chen R,Zhang P,Huang Z,Thompson JR,Meng Y,Bai Y,Wang J,Zhuo M,Wang T,Huang Y,Wei L,Li J,Wang Z,Hu H,Yang P,Le L,Stenson PD,Li B,Liu X,Ball EV,An N,Huang Q,Zhang Y,Fan W,Zhang X,Li Y,Wang W,Katze MG,Su B,Nielsen R,Yang H,Wang J,Wang X,Wang J

Polymorphisms in eight host genes associated with control of HIV replication do not mediate elite control of viral replication in SIV-infected Indian rhesus macaques.
Immunogenetics58(12)1003-9(2006 Dec)
Weiler A,May GE,Qi Y,Wilson N,Watkins DI

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IL10 cDNA ORF clone, Macaca mulatta(Rhesus monkey)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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