DNALI1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DNALI1
Entrez Gene ID	7802
Full Name	dynein axonemal light intermediate chain 1
Synonyms	P28,dJ423B22.5,hp28
General protein information	Preferred Names dynein axonemal light intermediate chain 1 Names axonemal dynein light intermediate polypeptide 1 dJ423B22.5 (axonemal dynein light chain (hp28)) dynein, axonemal, light intermediate polypeptide 1 inner dynein arm light chain, axonemal inner dynein arm, homolog of clamydomonas
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p34.3
Summary	This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. [provided by RefSeq, Jul 2008].
Disorder MIM:	602135

mRNA and Protein(s)

mRNA	Protein	Name
XM_005271172.2	XP_005271229.1	axonemal dynein light intermediate polypeptide 1 isoform X1
NM_003462.3	NP_003453.2	axonemal dynein light intermediate polypeptide 1
NM_003462.5	NP_003453.3	axonemal dynein light intermediate polypeptide 1
NM_003462.4	NP_003453.3	axonemal dynein light intermediate polypeptide 1
XM_005271172.3	XP_005271229.1	axonemal dynein light intermediate polypeptide 1 isoform X1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004030	XP_318486.5
Homo sapiens (human)	DNALI1	NP_003453.2
Rattus norvegicus (Norway rat)	Dnali1	NP_001026817.1
Drosophila melanogaster (fruit fly)	CG6971	NP_650128.1
Xenopus tropicalis (tropical clawed frog)	dnali1	NP_001016687.1
Macaca mulatta (Rhesus monkey)	DNALI1	XP_001111996.1
Canis lupus familiaris (dog)	DNALI1	XP_539590.3
Bos taurus (cattle)	DNALI1	NP_001178228.2
Danio rerio (zebrafish)	dnali1	NP_001103584.2
Pan troglodytes (chimpanzee)	DNALI1	XP_001169634.1
Mus musculus (house mouse)	Dnali1	NP_780432.1
Danio rerio (zebrafish)	LOC100536814	XP_003200255.1
Gallus gallus (chicken)	DNALI1	XP_417762.3

Gene Ontology
Bibliography

Related articles in PubMed

Identification of a novel host protein interacting with Toxoplasma gondii toxofilin via a yeast two-hybrid system.
Li Y, Yu Z, Cui Y, Sun H, Li J, Yin K, Zhao G, Wang H, Huang B, Wei Q, Liu G, Kou J
Acta biochimica et biophysica Sinica50(4)425-427(2018 Apr)

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.
Dougherty GW, Loges NT, Klinkenbusch JA, Olbrich H, Pennekamp P, Menchen T, Raidt J, Wallmeier J, Werner C, Westermann C, Ruckert C, Mirra V, Hjeij R, Memari Y, Durbin R, Kolb-Kokocinski A, Praveen K, Kashef MA, Kashef S, Eghtedari F, Häffner K, Valmari P, Baktai G, Aviram M, Bentur L, Amirav I, Davis EE, Katsanis N, Brueckner M, Shaposhnykov A, Pigino G, Dworniczak B, Omran H
American journal of respiratory cell and molecular biology55(2)213-24(2016 08)

Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal Disorganization.
Jeanson L, Thomas L, Copin B, Coste A, Sermet-Gaudelus I, Dastot-Le Moal F, Duquesnoy P, Montantin G, Collot N, Tissier S, Papon JF, Clement A, Louis B, Escudier E, Amselem S, Legendre M
Human mutation37(8)776-85(2016 08)

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M, , Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr, , Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, Höhn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ, , Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD, , Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, Pärssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN
American journal of human genetics93(2)264-77(2013 Aug)

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.
Hjeij R, Lindstrand A, Francis R, Zariwala MA, Liu X, Li Y, Damerla R, Dougherty GW, Abouhamed M, Olbrich H, Loges NT, Pennekamp P, Davis EE, Carvalho CM, Pehlivan D, Werner C, Raidt J, Köhler G, Häffner K, Reyes-Mugica M, Lupski JR, Leigh MW, Rosenfeld M, Morgan LC, Knowles MR, Lo CW, Katsanis N, Omran H
American journal of human genetics93(2)357-67(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DNALI1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DNALI1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu107027	NM_003462.5 Latest version!	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu13976	NM_003462.3 Latest version!	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu33772	XM_005271172.3 Latest version!	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu107027	NM_003462.4	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu33772	XM_005271172.2	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DNALI1 ( NM_003462.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003453.3 Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), mRNA.

Price & Availability↑

CloneID	OHu107027
Clone ID Related Accession (Same CDS sequence)	NM_003462.5 , NM_003462.4
Accession Version	NM_003462.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1565020800000
Organism	Homo sapiens(human)
Product	axonemal dynein light intermediate polypeptide 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX647913.1, BC046117.1 and BC039074.1. On May 17, 2019 this sequence version replaced NM_003462.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.59161.1, SRR1803615.42670.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000652629.1/ ENSP00000498620.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGATTCCGC CCGCAGACTC TTTGCTCAAG TACGACACCC CAGTGCTGGT GAGCCGGAAC 
ACGGAGAAAC GGAGCCCCAA GGCTCGGCTA CTGAAAGTCA GCCCCCAGCA GCCTGGACCT 
TCAGGTTCAG CCCCACAGCC ACCCAAGACC AAGCTCCCCT CAACTCCCTG TGTCCCAGAT 
CCTACAAAGC AGGCAGAAGA AATCTTGAAT GCCATACTAC CCCCAAGGGA GTGGGTGGAA 
GACACGCAGC TATGGATCCA GCAGGTGTCC AGCACCCCTA GCACCAGGAT GGACGTGGTG 
CACCTCCAGG AGCAGTTAGA CTTAAAGCTG CAGCAGCGGC AGGCCAGGGA AACAGGCATC 
TGCCCTGTCC GCAGGGAACT CTACTCACAG TGTTTTGATG AGTTGATCCG GGAGGTCACC 
ATCAACTGTG CGGAGAGGGG GCTGCTGCTG CTGCGAGTCC GGGACGAGAT CCGCATGACC 
ATCGCTGCCT ACCAGACCCT GTACGAGAGC AGCGTGGCGT TTGGCATGAG GAAGGCACTG 
CAGGCTGAGC AGGGGAAGTC AGACATGGAG AGGAAAATCG CAGAATTGGA GACGGAAAAG 
AGAGACCTGG AGAGGCAAGT GAACGAGCAG AAGGCAAAAT GTGAAGCCAC TGAGAAGCGG 
GAGAGCGAGA GGCGGCAGGT GGAGGAGAAG AAGCACAATG AGGAGATTCA GTTCCTGAAG 
CGAACAAATC AGCAGCTGAA GGCCCAACTG GAAGGCATTA TTGCACCAAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003453.3
CDS	56..832
Translation	MIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGSAPQPPKTKLPSTPCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

Target ORF information:

RefSeq Version	NM_003462.5
Organism	Homo sapiens(human)
Definition	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003462.5

ORF Insert Sequence:

ATGATTCCGC CCGCAGACTC TTTGCTCAAG TACGACACCC CAGTGCTGGT GAGCCGGAAC 
ACGGAGAAAC GGAGCCCCAA GGCTCGGCTA CTGAAAGTCA GCCCCCAGCA GCCTGGACCT 
TCAGGTTCAG CCCCACAGCC ACCCAAGACC AAGCTCCCCT CAACTCCCTG TGTCCCAGAT 
CCTACAAAGC AGGCAGAAGA AATCTTGAAT GCCATACTAC CCCCAAGGGA GTGGGTGGAA 
GACACGCAGC TATGGATCCA GCAGGTGTCC AGCACCCCTA GCACCAGGAT GGACGTGGTG 
CACCTCCAGG AGCAGTTAGA CTTAAAGCTG CAGCAGCGGC AGGCCAGGGA AACAGGCATC 
TGCCCTGTCC GCAGGGAACT CTACTCACAG TGTTTTGATG AGTTGATCCG GGAGGTCACC 
ATCAACTGTG CGGAGAGGGG GCTGCTGCTG CTGCGAGTCC GGGACGAGAT CCGCATGACC 
ATCGCTGCCT ACCAGACCCT GTACGAGAGC AGCGTGGCGT TTGGCATGAG GAAGGCACTG 
CAGGCTGAGC AGGGGAAGTC AGACATGGAG AGGAAAATCG CAGAATTGGA GACGGAAAAG 
AGAGACCTGG AGAGGCAAGT GAACGAGCAG AAGGCAAAAT GTGAAGCCAC TGAGAAGCGG 
GAGAGCGAGA GGCGGCAGGT GGAGGAGAAG AAGCACAATG AGGAGATTCA GTTCCTGAAG 
CGAACAAATC AGCAGCTGAA GGCCCAACTG GAAGGCATTA TTGCACCAAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNALI1 ( NM_003462.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003453.3 Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), mRNA.

Price & Availability↑

CloneID	OHu107027
Clone ID Related Accession (Same CDS sequence)	NM_003462.5 , NM_003462.4
Accession Version	NM_003462.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1539273600000
Organism	Homo sapiens(human)
Product	axonemal dynein light intermediate polypeptide 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX647913.1, BC046117.1 and BC039074.1. On Jun 30, 2018 this sequence version replaced NM_003462.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC046117.1, BC039074.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATTCCGC CCGCAGACTC TTTGCTCAAG TACGACACCC CAGTGCTGGT GAGCCGGAAC 
ACGGAGAAAC GGAGCCCCAA GGCTCGGCTA CTGAAAGTCA GCCCCCAGCA GCCTGGACCT 
TCAGGTTCAG CCCCACAGCC ACCCAAGACC AAGCTCCCCT CAACTCCCTG TGTCCCAGAT 
CCTACAAAGC AGGCAGAAGA AATCTTGAAT GCCATACTAC CCCCAAGGGA GTGGGTGGAA 
GACACGCAGC TATGGATCCA GCAGGTGTCC AGCACCCCTA GCACCAGGAT GGACGTGGTG 
CACCTCCAGG AGCAGTTAGA CTTAAAGCTG CAGCAGCGGC AGGCCAGGGA AACAGGCATC 
TGCCCTGTCC GCAGGGAACT CTACTCACAG TGTTTTGATG AGTTGATCCG GGAGGTCACC 
ATCAACTGTG CGGAGAGGGG GCTGCTGCTG CTGCGAGTCC GGGACGAGAT CCGCATGACC 
ATCGCTGCCT ACCAGACCCT GTACGAGAGC AGCGTGGCGT TTGGCATGAG GAAGGCACTG 
CAGGCTGAGC AGGGGAAGTC AGACATGGAG AGGAAAATCG CAGAATTGGA GACGGAAAAG 
AGAGACCTGG AGAGGCAAGT GAACGAGCAG AAGGCAAAAT GTGAAGCCAC TGAGAAGCGG 
GAGAGCGAGA GGCGGCAGGT GGAGGAGAAG AAGCACAATG AGGAGATTCA GTTCCTGAAG 
CGAACAAATC AGCAGCTGAA GGCCCAACTG GAAGGCATTA TTGCACCAAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003453.3
CDS	56..832
Translation	MIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGSAPQPPKTKLPSTPCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

Target ORF information:

RefSeq Version	NM_003462.4
Organism	Homo sapiens(human)
Definition	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003462.4

ORF Insert Sequence:

ATGATTCCGC CCGCAGACTC TTTGCTCAAG TACGACACCC CAGTGCTGGT GAGCCGGAAC 
ACGGAGAAAC GGAGCCCCAA GGCTCGGCTA CTGAAAGTCA GCCCCCAGCA GCCTGGACCT 
TCAGGTTCAG CCCCACAGCC ACCCAAGACC AAGCTCCCCT CAACTCCCTG TGTCCCAGAT 
CCTACAAAGC AGGCAGAAGA AATCTTGAAT GCCATACTAC CCCCAAGGGA GTGGGTGGAA 
GACACGCAGC TATGGATCCA GCAGGTGTCC AGCACCCCTA GCACCAGGAT GGACGTGGTG 
CACCTCCAGG AGCAGTTAGA CTTAAAGCTG CAGCAGCGGC AGGCCAGGGA AACAGGCATC 
TGCCCTGTCC GCAGGGAACT CTACTCACAG TGTTTTGATG AGTTGATCCG GGAGGTCACC 
ATCAACTGTG CGGAGAGGGG GCTGCTGCTG CTGCGAGTCC GGGACGAGAT CCGCATGACC 
ATCGCTGCCT ACCAGACCCT GTACGAGAGC AGCGTGGCGT TTGGCATGAG GAAGGCACTG 
CAGGCTGAGC AGGGGAAGTC AGACATGGAG AGGAAAATCG CAGAATTGGA GACGGAAAAG 
AGAGACCTGG AGAGGCAAGT GAACGAGCAG AAGGCAAAAT GTGAAGCCAC TGAGAAGCGG 
GAGAGCGAGA GGCGGCAGGT GGAGGAGAAG AAGCACAATG AGGAGATTCA GTTCCTGAAG 
CGAACAAATC AGCAGCTGAA GGCCCAACTG GAAGGCATTA TTGCACCAAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNALI1 ( NM_003462.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003453.2 Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), mRNA.

Price & Availability↑

CloneID	OHu13976
Clone ID Related Accession (Same CDS sequence)	NM_003462.3
Accession Version	NM_003462.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1506700800000
Organism	Homo sapiens(human)
Product	axonemal dynein light intermediate polypeptide 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX647913.1, BC046117.1 and BC039074.1. On Oct 9, 2003 this sequence version replaced NM_003462.2. ##Evidence-Data-START## Transcript exon combination :: BX647913.1, BC039074.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGACGG CAAACAAGGC CCACACTGGA CAGGGCAGCT GCTGGGTTGC TACTCTCGCC 
TCCGCCATGA TTCCGCCCGC AGACTCTTTG CTCAAGTACG ACACCCCAGT GCTGGTGAGC 
CGGAACACGG AGAAACGGAG CCCCAAGGCT CGGCTACTGA AAGTCAGCCC CCAGCAGCCT 
GGACCTTCAG GTTCAGCCCC ACAGCCACCC AAGACCAAGC TCCCCTCAAC TCCCTGTGTC 
CCAGATCCTA CAAAGCAGGC AGAAGAAATC TTGAATGCCA TACTACCCCC AAGGGAGTGG 
GTGGAAGACA CGCAGCTATG GATCCAGCAG GTGTCCAGCA CCCCTAGCAC CAGGATGGAC 
GTGGTGCACC TCCAGGAGCA GTTAGACTTA AAGCTGCAGC AGCGGCAGGC CAGGGAAACA 
GGCATCTGCC CTGTCCGCAG GGAACTCTAC TCACAGTGTT TTGATGAGTT GATCCGGGAG 
GTCACCATCA ACTGTGCGGA GAGGGGGCTG CTGCTGCTGC GAGTCCGGGA CGAGATCCGC 
ATGACCATCG CTGCCTACCA GACCCTGTAC GAGAGCAGCG TGGCGTTTGG CATGAGGAAG 
GCACTGCAGG CTGAGCAGGG GAAGTCAGAC ATGGAGAGGA AAATCGCAGA ATTGGAGACG 
GAAAAGAGAG ACCTGGAGAG GCAAGTGAAC GAGCAGAAGG CAAAATGTGA AGCCACTGAG 
AAGCGGGAGA GCGAGAGGCG GCAGGTGGAG GAGAAGAAGC ACAATGAGGA GATTCAGTTC 
CTGAAGCGAA CAAATCAGCA GCTGAAGGCC CAACTGGAAG GCATTATTGC ACCAAAGAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003453.2
CDS	11..853
Translation	MVTANKAHTGQGSCWVATLASAMIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGSAPQPPKTKLPSTPCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

Target ORF information:

RefSeq Version	NM_003462.3
Organism	Homo sapiens(human)
Definition	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003462.3

ORF Insert Sequence:

ATGGTGACGG CAAACAAGGC CCACACTGGA CAGGGCAGCT GCTGGGTTGC TACTCTCGCC 
TCCGCCATGA TTCCGCCCGC AGACTCTTTG CTCAAGTACG ACACCCCAGT GCTGGTGAGC 
CGGAACACGG AGAAACGGAG CCCCAAGGCT CGGCTACTGA AAGTCAGCCC CCAGCAGCCT 
GGACCTTCAG GTTCAGCCCC ACAGCCACCC AAGACCAAGC TCCCCTCAAC TCCCTGTGTC 
CCAGATCCTA CAAAGCAGGC AGAAGAAATC TTGAATGCCA TACTACCCCC AAGGGAGTGG 
GTGGAAGACA CGCAGCTATG GATCCAGCAG GTGTCCAGCA CCCCTAGCAC CAGGATGGAC 
GTGGTGCACC TCCAGGAGCA GTTAGACTTA AAGCTGCAGC AGCGGCAGGC CAGGGAAACA 
GGCATCTGCC CTGTCCGCAG GGAACTCTAC TCACAGTGTT TTGATGAGTT GATCCGGGAG 
GTCACCATCA ACTGTGCGGA GAGGGGGCTG CTGCTGCTGC GAGTCCGGGA CGAGATCCGC 
ATGACCATCG CTGCCTACCA GACCCTGTAC GAGAGCAGCG TGGCGTTTGG CATGAGGAAG 
GCACTGCAGG CTGAGCAGGG GAAGTCAGAC ATGGAGAGGA AAATCGCAGA ATTGGAGACG 
GAAAAGAGAG ACCTGGAGAG GCAAGTGAAC GAGCAGAAGG CAAAATGTGA AGCCACTGAG 
AAGCGGGAGA GCGAGAGGCG GCAGGTGGAG GAGAAGAAGC ACAATGAGGA GATTCAGTTC 
CTGAAGCGAA CAAATCAGCA GCTGAAGGCC CAACTGGAAG GCATTATTGC ACCAAAGAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNALI1 ( XM_005271172.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005271229.1 Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu33772
Clone ID Related Accession (Same CDS sequence)	XM_005271172.2 , XM_005271172.3
Accession Version	XM_005271172.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1465056000000
Organism	Homo sapiens(human)
Product	axonemal dynein light intermediate polypeptide 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005271172.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCATACT ACCCCCAAGA TGAGTTGATC CGGGAGGTCA CCATCAACTG TGCGGAGAGG 
GGGCTGCTGC TGCTGCGAGT CCGGGACGAG ATCCGCATGA CCATCGCTGC CTACCAGACC 
CTGTACGAGA GCAGCGTGGC GTTTGGCATG AGGAAGGCAC TGCAGGCTGA GCAGGGGAAG 
TCAGACATGG AGAGGAAAAT CGCAGAATTG GAGACGGAAA AGAGAGACCT GGAGAGGCAA 
GTGAACGAGC AGAAGGCAAA ATGTGAAGCC ACTGAGAAGC GGGAGAGCGA GAGGCGGCAG 
GTGGAGGAGA AGAAGCACAA TGAGGAGATT CAGTTCCTGA AGCGAACAAA TCAGCAGCTG 
AAGGCCCAAC TGGAAGGCAT TATTGCACCA AAGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005271229.1
CDS	267..665
Translation	MPYYPQDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

Target ORF information:

RefSeq Version	XM_005271172.2
Organism	Homo sapiens(human)
Definition	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005271172.2

ORF Insert Sequence:

ATGCCATACT ACCCCCAAGA TGAGTTGATC CGGGAGGTCA CCATCAACTG TGCGGAGAGG 
GGGCTGCTGC TGCTGCGAGT CCGGGACGAG ATCCGCATGA CCATCGCTGC CTACCAGACC 
CTGTACGAGA GCAGCGTGGC GTTTGGCATG AGGAAGGCAC TGCAGGCTGA GCAGGGGAAG 
TCAGACATGG AGAGGAAAAT CGCAGAATTG GAGACGGAAA AGAGAGACCT GGAGAGGCAA 
GTGAACGAGC AGAAGGCAAA ATGTGAAGCC ACTGAGAAGC GGGAGAGCGA GAGGCGGCAG 
GTGGAGGAGA AGAAGCACAA TGAGGAGATT CAGTTCCTGA AGCGAACAAA TCAGCAGCTG 
AAGGCCCAAC TGGAAGGCAT TATTGCACCA AAGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DNALI1 ( XM_005271172.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005271229.1 Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), transcript variant X1, mRNA.

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CloneID	OHu33772
Clone ID Related Accession (Same CDS sequence)	XM_005271172.2 , XM_005271172.3
Accession Version	XM_005271172.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 399bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1521907200000
Organism	Homo sapiens(human)
Product	axonemal dynein light intermediate polypeptide 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005271172.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCATACT ACCCCCAAGA TGAGTTGATC CGGGAGGTCA CCATCAACTG TGCGGAGAGG 
GGGCTGCTGC TGCTGCGAGT CCGGGACGAG ATCCGCATGA CCATCGCTGC CTACCAGACC 
CTGTACGAGA GCAGCGTGGC GTTTGGCATG AGGAAGGCAC TGCAGGCTGA GCAGGGGAAG 
TCAGACATGG AGAGGAAAAT CGCAGAATTG GAGACGGAAA AGAGAGACCT GGAGAGGCAA 
GTGAACGAGC AGAAGGCAAA ATGTGAAGCC ACTGAGAAGC GGGAGAGCGA GAGGCGGCAG 
GTGGAGGAGA AGAAGCACAA TGAGGAGATT CAGTTCCTGA AGCGAACAAA TCAGCAGCTG 
AAGGCCCAAC TGGAAGGCAT TATTGCACCA AAGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005271229.1
CDS	267..665
Translation	MPYYPQDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

Target ORF information:

RefSeq Version	XM_005271172.3
Organism	Homo sapiens(human)
Definition	Homo sapiens dynein axonemal light intermediate chain 1 (DNALI1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005271172.3

ORF Insert Sequence:

ATGCCATACT ACCCCCAAGA TGAGTTGATC CGGGAGGTCA CCATCAACTG TGCGGAGAGG 
GGGCTGCTGC TGCTGCGAGT CCGGGACGAG ATCCGCATGA CCATCGCTGC CTACCAGACC 
CTGTACGAGA GCAGCGTGGC GTTTGGCATG AGGAAGGCAC TGCAGGCTGA GCAGGGGAAG 
TCAGACATGG AGAGGAAAAT CGCAGAATTG GAGACGGAAA AGAGAGACCT GGAGAGGCAA 
GTGAACGAGC AGAAGGCAAA ATGTGAAGCC ACTGAGAAGC GGGAGAGCGA GAGGCGGCAG 
GTGGAGGAGA AGAAGCACAA TGAGGAGATT CAGTTCCTGA AGCGAACAAA TCAGCAGCTG 
AAGGCCCAAC TGGAAGGCAT TATTGCACCA AAGAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of a novel host protein interacting with Toxoplasma gondii toxofilin via a yeast two-hybrid system.
Acta biochimica et biophysica Sinica50(4)425-427(2018 Apr)
Li Y,Yu Z,Cui Y,Sun H,Li J,Yin K,Zhao G,Wang H,Huang B,Wei Q,Liu G,Kou J

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.
American journal of respiratory cell and molecular biology55(2)213-24(2016 08)
Dougherty GW,Loges NT,Klinkenbusch JA,Olbrich H,Pennekamp P,Menchen T,Raidt J,Wallmeier J,Werner C,Westermann C,Ruckert C,Mirra V,Hjeij R,Memari Y,Durbin R,Kolb-Kokocinski A,Praveen K,Kashef MA,Kashef S,Eghtedari F,Häffner K,Valmari P,Baktai G,Aviram M,Bentur L,Amirav I,Davis EE,Katsanis N,Brueckner M,Shaposhnykov A,Pigino G,Dworniczak B,Omran H

Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal Disorganization.
Human mutation37(8)776-85(2016 08)
Jeanson L,Thomas L,Copin B,Coste A,Sermet-Gaudelus I,Dastot-Le Moal F,Duquesnoy P,Montantin G,Collot N,Tissier S,Papon JF,Clement A,Louis B,Escudier E,Amselem S,Legendre M

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
American journal of human genetics93(2)264-77(2013 Aug)
Cheng CY,Schache M,Ikram MK,Young TL,Guggenheim JA,Vitart V,MacGregor S,Verhoeven VJ,Barathi VA,Liao J,Hysi PG,Bailey-Wilson JE,St Pourcain B,Kemp JP,McMahon G,Timpson NJ,Evans DM,Montgomery GW,Mishra A,Wang YX,Wang JJ,Rochtchina E,Polasek O,Wright AF,Amin N,van Leeuwen EM,Wilson JF,Pennell CE,van Duijn CM,de Jong PT,Vingerling JR,Zhou X,Chen P,Li R,Tay WT,Zheng Y,Chew M,,Burdon KP,Craig JE,Iyengar SK,Igo RP Jr,Lass JH Jr,,Chew EY,Haller T,Mihailov E,Metspalu A,Wedenoja J,Simpson CL,Wojciechowski R,Höhn R,Mirshahi A,Zeller T,Pfeiffer N,Lackner KJ,,Bettecken T,Meitinger T,Oexle K,Pirastu M,Portas L,Nag A,Williams KM,Yonova-Doing E,Klein R,Klein BE,Hosseini SM,Paterson AD,,Makela KM,Lehtimaki T,Kahonen M,Raitakari O,Yoshimura N,Matsuda F,Chen LJ,Pang CP,Yip SP,Yap MK,Meguro A,Mizuki N,Inoko H,Foster PJ,Zhao JH,Vithana E,Tai ES,Fan Q,Xu L,Campbell H,Fleck B,Rudan I,Aung T,Hofman A,Uitterlinden AG,Bencic G,Khor CC,Forward H,Pärssinen O,Mitchell P,Rivadeneira F,Hewitt AW,Williams C,Oostra BA,Teo YY,Hammond CJ,Stambolian D,Mackey DA,Klaver CC,Wong TY,Saw SM,Baird PN

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.
American journal of human genetics93(2)357-67(2013 Aug)
Hjeij R,Lindstrand A,Francis R,Zariwala MA,Liu X,Li Y,Damerla R,Dougherty GW,Abouhamed M,Olbrich H,Loges NT,Pennekamp P,Davis EE,Carvalho CM,Pehlivan D,Werner C,Raidt J,Köhler G,Häffner K,Reyes-Mugica M,Lupski JR,Leigh MW,Rosenfeld M,Morgan LC,Knowles MR,Lo CW,Katsanis N,Omran H

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DNALI1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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