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Xenopus tropicalis (tropical clawed frog)


RNA Polymerase II Transcription Elongation Formation of RNA Pol II elongation complex
Transport of Mature mRNA derived from an Intron-Containing Transcript Processing of Capped Intronless Pre-mRNA
SLBP independent Processing of Histone Pre-mRNAs Formation of the Editosome
C6 deamination of adenosine Nonsense-Mediated Decay (NMD)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Post-transcriptional silencing by small RNAs HuR (ELAVL1) binds and stabilizes mRNA
Translation Eukaryotic Translation Initiation
Cap-dependent Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
L13a-mediated translational silencing of Ceruloplasmin expression snRNP Assembly
TET1,2,3 and TDG demethylate DNA Collagen formation
Collagen biosynthesis and modifying enzymes Laminin interactions
ECM proteoglycans Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases Mitochondrial translation
Cilium Assembly Cargo trafficking to the periciliary membrane
Metabolism of proteins Association of TriC/CCT with target proteins during biosynthesis
Synthesis of glycosylphosphatidylinositol (GPI) N-glycan antennae elongation in the medial/trans-Golgi
O-linked glycosylation O-linked glycosylation of mucins
Termination of O-glycan biosynthesis SUMO is conjugated to E1 (UBA2:SAE1)
SUMOylation of DNA damage response and repair proteins Glycoprotein hormones
Mitophagy Ligand-dependent caspase activation
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Release of apoptotic factors from the mitochondria
SMAC-mediated apoptotic response Caspase-mediated cleavage of cytoskeletal proteins
Breakdown of the nuclear lamina Cell Cycle Checkpoints
Transcriptional activation of p53 responsive genes G2/M DNA damage checkpoint
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Inactivation of APC/C via direct inhibition of the APC/C complex Mitotic G1-G1/S phases
G1 Phase G1/S Transition
Cyclin E associated events during G1/S transition Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
E2F mediated regulation of DNA replication CDK-mediated phosphorylation and removal of Cdc6
Removal of the Flap Intermediate G2 Phase
Centrosome maturation Recruitment of NuMA to mitotic centrosomes
Loss of proteins required for interphase microtubule organization from the centrosome Nuclear Pore Complex (NPC) Disassembly
Mitotic Prometaphase Resolution of Sister Chromatid Cohesion
Nuclear Envelope Reassembly M/G1 Transition
DNA Replication Pre-Initiation Cdc20:Phospho-APC/C mediated degradation of Cyclin A
APC-Cdc20 mediated degradation of Nek2A Chromosome Maintenance
Polymerase switching on the C-strand of the telomere Removal of the Flap Intermediate from the C-strand
Cardiac conduction Neuronal System
Transmission across Chemical Synapses GABA synthesis
Dopamine clearance from the synaptic cleft Metabolism of serotonin
Trafficking of AMPA receptors CREB phosphorylation through the activation of Adenylate Cyclase
Transmembrane transport of small molecules Cation-coupled Chloride cotransporters
Multifunctional anion exchangers Sodium-coupled phosphate cotransporters
Class II GLUTs Proton-coupled monocarboxylate transport
Iron uptake and transport Ligand-gated ion channel transport
Stimuli-sensing channels Signal Transduction
EGFR interacts with phospholipase C-gamma DAG and IP3 signaling
Cam-PDE 1 activation GRB2 events in EGFR signaling
RAF/MAP kinase cascade Signaling by FGFR1
FGFR1 ligand binding and activation FGFR1b ligand binding and activation
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