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Xenopus tropicalis (tropical clawed frog)


Metabolism of fat-soluble vitamins Vitamin D (calciferol) metabolism
Metabolism of amino acids and derivatives Methionine salvage pathway
Regulation of ornithine decarboxylase (ODC) Urea cycle
Serotonin and melatonin biosynthesis Degradation of cysteine and homocysteine
Sulfide oxidation to sulfate Metabolism of ingested MeSeO2H into MeSeH
Metabolism of porphyrins Heme biosynthesis
Phase 1 - Functionalization of compounds Endogenous sterols
Vitamins Glutathione conjugation
CRMPs in Sema3A signaling Other semaphorin interactions
NCAM1 interactions Role of Abl in Robo-Slit signaling
EPH-Ephrin signaling EPHA-mediated growth cone collapse
Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells Clathrin-mediated endocytosis
VLDL biosynthesis Activation of CaMK IV
DNA Damage Reversal UCH proteinases
Ub-specific processing proteases Ovarian tumor domain proteases
Metalloprotease DUBs RAB geranylgeranylation
Protein methylation HDACs deacetylate histones
p75NTR signals via NF-kB Axonal growth stimulation
ARMS-mediated activation PLC-gamma1 signalling
Retrograde neurotrophin signalling Nuclear Events (kinase and transcription factor activation)
ERKs are inactivated Signaling by VEGF
VEGFA-VEGFR2 Pathway VEGFR2 mediated cell proliferation
Regulation of KIT signaling Downregulation of ERBB2:ERBB3 signaling
ERBB2 Activates PTK6 Signaling Nuclear signaling by ERBB4
Prolactin receptor signaling MAPK1/MAPK3 signaling
MAPK6/MAPK4 signaling RHO GTPases activate PKNs
RHO GTPases activate KTN1 RHO GTPases Activate Formins
Signaling by BMP TGF-beta receptor signaling activates SMADs
Signaling by NOTCH Signaling by NOTCH1
Activated NOTCH1 Transmits Signal to the Nucleus Signaling by GPCR
Amine ligand-binding receptors Serotonin receptors
Hormone ligand-binding receptors Leukotriene receptors
Adenosine P1 receptors Effects of PIP2 hydrolysis
G-protein beta:gamma signalling Adenylate cyclase activating pathway
Degradation of beta-catenin by the destruction complex TCF dependent signaling in response to WNT
WNT mediated activation of DVL Beta-catenin independent WNT signaling
WNT5A-dependent internalization of FZD4 Signaling by Hippo
SHC-related events triggered by IGF1R Signaling by Leptin
Integrin alphaIIb beta3 signaling Degradation of GLI1 by the proteasome
CD28 co-stimulation CD28 dependent Vav1 pathway
Antigen Presentation: Folding, assembly and peptide loading of class I MHC Cross-presentation of soluble exogenous antigens (endosomes)
Toll-Like Receptors Cascades MAPK targets/ Nuclear events mediated by MAP kinases
Toll Like Receptor 7/8 (TLR7/8) Cascade MyD88 dependent cascade initiated on endosome
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Toll Like Receptor 4 (TLR4) Cascade
Creation of C4 and C2 activators Lectin pathway of complement activation
Classical antibody-mediated complement activation Terminal pathway of complement
Cytosolic sensors of pathogen-associated DNA RIP-mediated NFkB activation via ZBP1
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production DAP12 interactions
FCERI mediated Ca+2 mobilization Dectin-1 mediated noncanonical NF-kB signaling
Signaling by Interleukins Interleukin-1 signaling
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