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Overview

GenScript's Plasmid DNA Preparation Service is accommodating to both small research labs as well as large-scale manufacturing biotech and pharmaceutical companies, providing you with high quality plasmids with 100% full insert sequence accuracy. Choose from a variety of our packages to help you achieve highly efficient cell transfection, and to support your DNA vaccine development, antibody production, and other preclinical research projects. Request a quote now for New plasmids to be synthesized, or Re-prep of previously synthesized plasmid.

Grades and Applications

With close to 20 years of CRO experience, GenScript truly understands your needs. From transformation to extraction, we have developed a robust protocol with years of process optimization to provide you top-notch quality plasmid preps with fully customizable services.

Research Grade

Plasmid prep shouldn't be a time and energy-consuming job in your lab! Highly economical, GenScript's research grade plasmid DNA can help you with standard preps for cloning, mutagenesis and transformation. From microgram- to gram-scale with reliable quality and fast turnaround time to accommodate tight deadlines.

Industrial Grade

Are uncontrolled or unexplained failures in your plasmid prep causing reproducibility issues and delays in your experiments? GenScript's Industrial Grade Plasmid DNA can help your experiments achieve highly efficient cell transfection, helping to improve experimental outcomes in research areas such as protein expression, antibody production, and other research projects.

Pre-clinical Grade

GenScript offers preclinical grade plasmids with the most comprehensive and stringent quality specifications and analysis for your preclinical project needs. Ideal for preclinical in vivo animal studies, from mice to non-human primates, in gene therapy, cell therapy, and vaccine research. Available in quantities of 10 mg and up.

Specs Research Grade Industrial Grade HT Grade Pre-clinical Grade
Price From $39 From $99 From $29 From $1199
Volume 100 µg-2 g 100 µg-2 g 10 µg-30 µg 10 mg-2 g
Turnaround Time From 2BD (bundled) From 8BD
(stand alone)		 From 2BD (bundled) From 8BD
(stand alone)		 From 2BD (bundled) From 9BD
(stand alone)		 From 2BD (bundled) From 9BD
(stand alone)
Homogeneity Predominantly supercoiled ≥90±10% supercoiled ≥90±10% supercoiled ≥90% supercoiled
Endotoxin - Quantitative LAL assay
<0.01 EU/µg		 Quantitative LAL assay
<0.1 EU/µg		 Quantitative LAL assay
≤0.01 EU/µg
or
≤0.005 EU/µg
Residual RNA Non-detectable by gel electrophoresis at 200ng
Residual E. coli DNA Non-detectable by gel electrophoresis Quantitative PCR
≤ 5%
Residual Host Protein - HCP ELISA ≤1%
Bioburden Testing - No growth on agar plate after 48 hours
Animal Free Production* Available with additional charge
Enzyme Free Production - Available with additional charge
Advanced Endotoxin Removal <0.005 EU/µg - Available with additional charge
Mycoplasma Contamination - Available with additional charge
Material Archiving - Available with additional charge
Appearance Clear, colorless, no visible particulates
A260:280 1.8 - 2.0
pH - 8.0 ± 0.5 (in TE buffer)
7.4 ± 0.5 (in PBS buffer)
(5-7) ± 0.5 (in ddH2O buffer)
Restriction Analysis Conforming to reference pattern

*:For research, industrial and HT grade plasmid preps: Since densitometry is semi quantitative, the genomic DNA is considered nonvisible if the comparative intensity of genomic DNA < 15% of plasmid band. Quantitative genomic DNA measurement by qPCR is available with additional charges.
**: Sequence verification of the full gene insert only applies when bundled with gene synthesis (an insert to be cloned into a plasmid).
***: Percentage of supercoiled plasmid may vary when analyzing with different methods or can be altered due to shipping conditions.

Additional QC available upon request

Animal Free Statement Plasmid Prep QC
Molecular Biology

Additional Resources

industrial grade plasmid flyer
Industrial Grade Plasmid Service

A 100% Full Insert Sequence Accuracy, Guaranteed

Free Download
preclinical grade plasmids flyer
Preclinical Grade Plasmids

With the most comprehensive and stringent QC
Tailored for preclinical studies

Free Download

GLP Plasmid Prep Services

As a leading biotech company and the largest gene synthesis supplier in the USA, GenScript has accumulated a wealth of experience in GLP-level plasmid preparation.
We are happy to offer GLP plasmid prep services to provide you with ultra transparent documentation system and communication.

Strict

Operating Procedurces

Comprehensive

Final Report

Data Archive

Management

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Testimonials

KansasState Dr. Melissa A. Melan

University of Pittsburgh
Medical Center,
USA

We used GenScript's plasmid preparation service to prepare large quantities of plasmids that contain our Southern blot probe fragments. This saved our lab considerable time and expense. From the initial order to service delivery, GenScript provided our lab with timely follow-ups and valuable advice. We now have an adequate supply of these probes with no need to grow bacterial cultures every time a new probe is required. Thank you, GenScript!

Customer Reviews

1 Customer Reviews

4.5 out of 5 stars
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EMAIL

gene@genscript.com

PHONE

1-877-436-7274

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