Peptide News

Overview

Immune checkpoints provide broad and diverse opportunities to enhance T cell activity that can increase anti-tumor immunity, potentially resulting in durable clinical responses. GenScript has developed overexpression cell line products expressing the most popular co-inhibitory and co-stimulatory immune checkpoints of human, mouse and cynomolgus monkey origin to accelerate immunotherapy discovery and clinical translation.

Highlights

Single clone

Single clone

Multiple Species

Multiple Species

Guaranteed performance

Guaranteed performance

Stringent QC standards

Stringent QC standards

Stable Cell Lines

Applications

Screening antibodies binding with immune checkpoints

Evaluating binding affinity between antibodies with immune checkpoints

Using as immunogen for antibody development

Receptor List

Co-Inhibitory Immune Checkpoints
PD-1 PD-L1 PD-L2 CTLA4 LAG3
TIGIT TIM3 VISTA BDCA2 BTLA
KIR CD38 CD47 CD80 CD86
CD103 / ITGAE CD155 / PVR CD200 R1
Co-Stimulatory Immune Checkpoints
4-1BB OX40 GITR ICOS B7-H2 / ICOSLG
B7-H3 / CD276 B7-H4 HVEM

Product List

PD-1

Cell Line Cat.No.
CHO-K1/PD-1 M00529
CHO-K1/mouse PD-1 M00552
CHO-K1/cyno PD-1 M00572
Daudi/PD-1 M00630

PD-L1

Cell Line Cat.No.
HEK293/PD-L1 M00544
CHO-K1/PD-L1 M00543
CHO-K1/mouse PD-L1 M00567
CHO-K1/cyno PD-L1 M00573

PD-L2

Cell Line Cat.No.
CHO-K1/PD-L2 M00627
CHO-K1/cyno PD-L2 M00629

CTLA4

Cell Line Cat.No.
CHO-K1/CTLA4 M00530
CHO-K1/mouse CTLA4 M00570
CHO-K1/cyno CTLA4 M00571

Lag3

Cell Line Cat.No.
CHO-K1/Lag3 M00532

TIGIT

Cell Line Cat.No.
CHO-K1/TIGIT M00542
CHO-K1/mouse TIGIT M00585

Tim3

Cell Line Cat.No.
CHO-K1/Tim3 M00531

VISTA

Cell Line Cat.No.
CHO-K1/VISTA M00533
CHO-K1/Mouse VISTA M00633
CHO-K1/Cyno VISTA M00634

BDCA2

Cell Line Cat.No.
CHO-K1/BDCA2 M00595
CHO-K1/Cyno BDCA2 M00596
CHO-K1/BDCA2 and FcER1G M00593
CHO-K1/ Cyno BDCA2 and FcER1G M00594

BTLA

Cell Line Cat.No.
CHO-K1/BTLA M00534

KIR

Cell Line Cat.No.
CHO-K1/KIR M00650

CD38

Cell Line Cat.No.
CHO-K1/human CD38 M00553
CHO-K1/mouse CD38 M00636

CD47

Cell Line Cat.No.
CHO-K1/CD47 M00581
CHO-K1/Mouse CD47 M00631
CHO-K1/Cyno CD47 M00632

CD80

Cell Line Cat.No.
CHO-K1/CD80 M00545

CD103

Cell Line Cat.No.
CHO-K1/ITGAE M00592

CD112

Cell Line Cat.No.
CHO-K1/CD112 M00590

CD155

Cell Line Cat.No.
CHO-K1/CD155 M00591
CHO-K1/Cyno CD155 M00643
CHO-K1/Mouse CD155 M00642

CD200 R1

Cell Line Cat.No.
CHO-K1/CD200 R1 M00541

4-1BB

Cell Line Cat.No.
CHO-K1/4-1BB M00538
CHO-K1/mouse 4-1BB M00568
CHO-K1/cyno 4-1BB M00569

OX-40

Cell Line Cat.No.
CHO-K1/OX-40 M00561

GITR

Cell Line Cat.No.
CHO-K1/GITR M00539

ICOS

Cell Line Cat.No.
CHO-K1/ICOS M00649

B7-H2

Cell Line Cat.No.
CHO-K1/B7-H2 M00671

B7-H3

Cell Line Cat.No.
CHO-K1/B7-H3 M00536

B7-H4

Cell Line Cat.No.
CHO-K1/B7-H4 M00537

HVEM

Cell Line Cat.No.
CHO-K1/HVEM M00646
CHO-K1/mouse HVEM M00647
CHO-K1/Cyno HVEM M00648

Resources

Stable Cell Lines Brochure
Stable Cell Lines Brochure

Cell line product catalog including brief introductions, product list and validations.

Free Download
Fc Receptor Cell Lines Flyer
Fc Receptor Cell Lines Flyer

Cell line product catalog including brief introductions, product list and validations.

Free Download

Related Products

Cas9 Plasmids
Fc Receptor Cell Lines
Cas9 Nucleases
Immune checkpoint antibodies

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EMAIL

product@genscript.com

PHONE

1-877-436-7274 (Toll-Free)
1-732-885-9188

ONLINE FORM

Online Quote Submission

ONLINE FORM

Online Quote Submission

FAX

1-732-210-0262