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Cardiac Troponin I (cTnI), His, Human

Recombinant Human Cardiac Troponin I (cTnI) produced in E. coli cells is a single non-glycosylated polypeptide chain containing 222 amino acids. rhcTnI has a molecular mass of 26 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Z03320
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Product Introduction
Species Human
Protein Construction
Poly-His cTnI (Ala2-Ser210)
Accession # P19429
N-term C-term
Purity > 95% as analyzed by SDS-PAGE
Expression System E. coli
Apparent Molecular Weight ~26 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized after extensive dialysis against 10 mM HCl.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

Background
Target Background Cardiac Troponin I (cTnI) is a subtype of the troponin family that is commonly used as a marker for myocardial damage. Cardiac troponin I is specific for cardiac tissue and is detected in the serum only if myocardial injury has occurred. Because cardiac troponin I is a very sensitive and specific indicator of heart muscle (myocardium) damage, serum levels can be used to help differentiate between unstable angina and myocardial infarction (heart attack) in people with chest pain or acute coronary syndrome.
Synonyms Human Cardiac Troponin I

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.