Catalog Products » Recombinant Proteins » MIP-3β/CCL19, Mouse

MIP-3β/CCL19, Mouse

Chemokine (C-C motif) ligand 19 (CCL19) is a small cytokine belonging to the CC chemokine family that is also known as EBI1 ligand chemokine (ELC) and macrophage inflammatory protein-3-beta (MIP-3-beta). It binds specifically to the chemokine receptor CCR7 / EBI1 / BLR2. CCL19 is expressed abundantly in thymus, lymph nodes and in activated bone marrow stromal cells. It attracts certain cells of the immune system, including dendritic cells and antigen-engaged B cells, CCR7+ central-memory T-Cells.
Z02903
$165.00

Ask us a question
Product Introduction
Species Mouse
Protein Construction
MIP-3β (Gly26-Ser108)
Accession # O70460
Purity > 97% as analyzed by SDS-PAGE
> 97% as analyzed by HPLC
Endotoxin Level < 1 EU/μg of protein by LAL method
Biological Activity Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human mature dendritic cells is in a concentration range of 10.0-100.0 ng/ml.
Expression System E. coli
Theoretical Molecular Weight 9.2 kDa
Formulation Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.

Background
Target Background Chemokine (C-C motif) ligand 19 (CCL19) is a small cytokine belonging to the CC chemokine family that is also known as EBI1 ligand chemokine (ELC) and macrophage inflammatory protein-3-beta (MIP-3-beta). It binds specifically to the chemokine receptor CCR7 / EBI1 / BLR2. CCL19 is expressed abundantly in thymus, lymph nodes and in activated bone marrow stromal cells. It attracts certain cells of the immune system, including dendritic cells and antigen-engaged B cells, CCR7+ central-memory T-Cells.
Synonyms CCL-19; CKb11; ELC; MIP-3b; MIP3B; SCYA19; C-C motif chemokine ligand 19

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.