Gene Symbol | PPP1R14A |
Entrez Gene ID | 397610 |
Full Name | protein phosphatase 1 regulatory inhibitor subunit 14A |
Synonyms | CPI17 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
Genome |
ORF » Species Summary » Sus scrofa » PPP1R14A cDNA ORF clone
Gene Symbol | PPP1R14A |
Entrez Gene ID | 397610 |
Full Name | protein phosphatase 1 regulatory inhibitor subunit 14A |
Synonyms | CPI17 |
Gene Type | protein-coding |
Organism | Sus scrofa(pig) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_021093577.1 | XP_020949236.1 | protein phosphatase 1 regulatory subunit 14A isoform X1 |
NM_214337.1 | NP_999502.1 | protein phosphatase 1 regulatory subunit 14A |
Tonic and phasic smooth muscle contraction is not regulated by the PKCα - CPI-17 pathway in swine stomach antrum and fundus.
Zhang Y, Hermanson ME, Eddinger TJ
PloS one8(9)e74608(2013)
Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor.
Eto M, Kitazawa T, Matsuzawa F, Aikawa S, Kirkbride JA, Isozumi N, Nishimura Y, Brautigan DL, Ohki SY
Structure (London, England : 1993)15(12)1591-602(2007 Dec)
A high resolution physical and RH map of pig chromosome 6q1.2 and comparative analysis with human chromosome 19q13.1.
Martins-Wess F, Milan D, Drögemüller C, Vobeta-Nemitz R, Brenig B, Robic A, Yerle M, Leeb T
BMC genomics4(1)20(2003 May)
Distinctive solution conformation of phosphatase inhibitor CPI-17 substituted with aspartate at the phosphorylation-site threonine residue.
Ohki Sy, Eto M, Shimizu M, Takada R, Brautigan DL, Kainosho M
Journal of molecular biology326(5)1539-47(2003 Mar)
Solution NMR structure of the myosin phosphatase inhibitor protein CPI-17 shows phosphorylation-induced conformational changes responsible for activation.
Ohki S, Eto M, Kariya E, Hayano T, Hayashi Y, Yazawa M, Brautigan D, Kainosho M
Journal of molecular biology314(4)839-49(2001 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following PPP1R14A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PPP1R14A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSe00209 | |
Clone ID Related Accession (Same CDS sequence) | NM_214337.1 | |
Accession Version | NM_214337.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 444bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1577116800000 | |
Organism | Sus scrofa(pig) | |
Product | protein phosphatase 1 regulatory subunit 14A | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB008376.1. ##Evidence-Data-START## Transcript exon combination :: AB008376.1, BP436636.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01048241, SAMN01048247 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCAGCTC AGCGGCTGGG CAAGCGGGTG CTGAGCAAGC TGCAGTCTCC GTCGCGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_999502.1 |
CDS | 23..466 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGCTC AGCGGCTGGG CAAGCGGGTG CTGAGCAAGC TGCAGTCTCC GTCGCGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSe250505 | |
Clone ID Related Accession (Same CDS sequence) | XM_021093577.1 | |
Accession Version | XM_021093577.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1494518400000 | |
Organism | Sus scrofa(pig) | |
Product | protein phosphatase 1 regulatory subunit 14A isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_010448.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Sus scrofa Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTC AGCGGCTGGG CAAGCGGGTG CTGAGCAAGC TGCAGTCTCC GTCGCGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_020949236.1 |
CDS | 266..676 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGCTC AGCGGCTGGG CAAGCGGGTG CTGAGCAAGC TGCAGTCTCC GTCGCGGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Tonic and phasic smooth muscle contraction is not regulated by the PKCα - CPI-17 pathway in swine stomach antrum and fundus. |
Phosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitor. |
A high resolution physical and RH map of pig chromosome 6q1.2 and comparative analysis with human chromosome 19q13.1. |
Distinctive solution conformation of phosphatase inhibitor CPI-17 substituted with aspartate at the phosphorylation-site threonine residue. |
Solution NMR structure of the myosin phosphatase inhibitor protein CPI-17 shows phosphorylation-induced conformational changes responsible for activation. |