Gene Symbol | BCO2 |
Entrez Gene ID | 100286796 |
Full Name | beta-carotene oxygenase 2 |
Gene Type | protein-coding |
Organism | Ovis aries(sheep) |
ORF » Species Summary » Ovis aries » BCO2 cDNA ORF clone
Gene Symbol | BCO2 |
Entrez Gene ID | 100286796 |
Full Name | beta-carotene oxygenase 2 |
Gene Type | protein-coding |
Organism | Ovis aries(sheep) |
mRNA | Protein | Name |
---|---|---|
XM_012095241.1 | XP_011950631.1 | beta,beta-carotene 9',10'-oxygenase isoform X2 |
NM_001159278.1 | NP_001152750.1 | beta,beta-carotene 9',10'-oxygenase |
XM_012095240.2 | XP_011950630.1 | beta,beta-carotene 9',10'-oxygenase isoform X1 |
NM_001159278.2 | NP_001152750.2 | beta,beta-carotene 9',10'-oxygenase |
XM_012095240.3 | XP_011950630.2 | beta,beta-carotene 9',10'-oxygenase isoform X1 |
Biallelic β-carotene oxygenase 2 knockout results in yellow fat in sheep via CRISPR/Cas9.
Niu Y, Jin M, Li Y, Li P, Zhou J, Wang X, Petersen B, Huang X, Kou Q, Chen Y
Animal genetics48(2)242-244(2017 Apr)
A nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene is tightly associated with accumulation of carotenoids in adipose tissue in sheep (Ovis aries).
Våge DI, Boman IA
BMC genetics1110(2010 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following BCO2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BCO2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSm21115 | |
Clone ID Related Accession (Same CDS sequence) | NM_001159278.1 | |
Accession Version | NM_001159278.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 198bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1549641600000 | |
Organism | Ovis aries(sheep) | |
Product | beta,beta-carotene 9',10'-oxygenase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from FN257487.1. ##Evidence-Data-START## Transcript exon combination :: FN257486.1, FN257487.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA104494983, SAMEA104494984 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTTTCCTG AACTCTTTCT ACGTTCAGTC AGCAGCTTTT CTACCATTGC AGTTGATTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001152750.1 |
CDS | 1..198 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTTTCCTG AACTCTTTCT ACGTTCAGTC AGCAGCTTTT CTACCATTGC AGTTGATTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSm22427 | |
Clone ID Related Accession (Same CDS sequence) | XM_012095241.1 | |
Accession Version | XM_012095241.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1413bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1450195200000 | |
Organism | Ovis aries(sheep) | |
Product | beta,beta-carotene 9',10'-oxygenase isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639024.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTTTAC TTCACCAGTT CAAGATGGAG AAGGGCACAG TGACATATAG GAGCAAGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011950631.1 |
CDS | 42..1454 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTTTAC TTCACCAGTT CAAGATGGAG AAGGGCACAG TGACATATAG GAGCAAGTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSm65115 | |
Clone ID Related Accession (Same CDS sequence) | NM_001159278.2 , XM_012095240.3 | |
Accession Version | NM_001159278.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1572105600000 | |
Organism | Ovis aries(sheep) | |
Product | beta,beta-carotene 9',10'-oxygenase | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from PEKD01003261.1 and FN257486.1. On or before Oct 28, 2019 this sequence version replaced XM_012095240.3, NM_001159278.1. ##Evidence-Data-START## Transcript exon combination :: FN257486.1, FN257487.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA104494983, SAMEA104494984 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTTTCCTG AACTCTTTCT ACGTTCAGTC AGCAGCTTTT CTACCATTGC AGTTGATTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001152750.2 |
CDS | 50..1777 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTTTCCTG AACTCTTTCT ACGTTCAGTC AGCAGCTTTT CTACCATTGC AGTTGATTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSm22426 | |
Clone ID Related Accession (Same CDS sequence) | XM_012095240.2 | |
Accession Version | XM_012095240.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1450195200000 | |
Organism | Ovis aries(sheep) | |
Product | beta,beta-carotene 9',10'-oxygenase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_014639024.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 17, 2015 this sequence version replaced XM_012095240.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Ovis aries Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTCCTG AACTCTTTCT ACGTTCAGTC AGCAGCTTTT CTACCATTGC AGTTGATTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011950630.1 |
CDS | 72..1799 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTTTCCTG AACTCTTTCT ACGTTCAGTC AGCAGCTTTT CTACCATTGC AGTTGATTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSm65115 | |
Clone ID Related Accession (Same CDS sequence) | NM_001159278.2 , XM_012095240.3 | |
Accession Version | XM_012095240.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1549296000000 | |
Organism | Ovis aries(sheep) | |
Product | beta,beta-carotene 9',10'-oxygenase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_040266.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 6, 2019 this sequence version replaced XM_012095240.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Ovis aries Annotation Release 103 Annotation Version :: 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTCCTG AACTCTTTCT ACGTTCAGTC AGCAGCTTTT CTACCATTGC AGTTGATTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011950630.2 |
CDS | 44..1771 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTTTCCTG AACTCTTTCT ACGTTCAGTC AGCAGCTTTT CTACCATTGC AGTTGATTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Biallelic β-carotene oxygenase 2 knockout results in yellow fat in sheep via CRISPR/Cas9. |
A nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene is tightly associated with accumulation of carotenoids in adipose tissue in sheep (Ovis aries). |