MKK2 cDNA ORF clone, Leishmania infantum JPCM5

Gene
Clones
gRNAs

Summary

Gene Symbol	MKK2
Entrez Gene ID	5067439
Full Name	mitogen-activated protein kinase kinase 2
Gene Type	protein-coding
Organism	Leishmania infantum JPCM5

mRNA and Protein(s)

mRNA	Protein	Name
XM_001464021.1	XP_001464058.1	mitogen-activated protein kinase kinase 2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
Rogers MB, Hilley JD, Dickens NJ, Wilkes J, Bates PA, Depledge DP, Harris D, Her Y, Herzyk P, Imamura H, Otto TD, Sanders M, Seeger K, Dujardin JC, Berriman M, Smith DF, Hertz-Fowler C, Mottram JC
Genome research21(12)2129-42(2011 Dec)

Comparative genomic analysis of three Leishmania species that cause diverse human disease.
Peacock CS, Seeger K, Harris D, Murphy L, Ruiz JC, Quail MA, Peters N, Adlem E, Tivey A, Aslett M, Kerhornou A, Ivens A, Fraser A, Rajandream MA, Carver T, Norbertczak H, Chillingworth T, Hance Z, Jagels K, Moule S, Ormond D, Rutter S, Squares R, Whitehead S, Rabbinowitsch E, Arrowsmith C, White B, Thurston S, Bringaud F, Baldauf SL, Faulconbridge A, Jeffares D, Depledge DP, Oyola SO, Hilley JD, Brito LO, Tosi LR, Barrell B, Cruz AK, Mottram JC, Smith DF, Berriman M
Nature genetics39(7)839-47(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MKK2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MKK2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OLc01258	XM_001464021.1 Latest version!	Leishmania infantum JPCM5 mitogen-activated protein kinase kinase 2 (MKK2), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MKK2 ( XM_001464021.1 ) cDNA ORF clone, Leishmania infantum JPCM5 -> XP_001464058.1 Leishmania infantum JPCM5 mitogen-activated protein kinase kinase 2 (MKK2), partial mRNA.

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CloneID	OLc01258
Clone ID Related Accession (Same CDS sequence)	XM_001464021.1
Accession Version	XM_001464021.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3273bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1436889600000
Organism	Leishmania infantum JPCM5
Product	mitogen-activated protein kinase kinase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_009397). COMPLETENESS: incomplete on both ends.

ATGCTTGTGA CGATGGAGAA CTACCAAATA ATCGAGTCCA TCGGAGAGGG CTCCTTTGGC 
AAAGTGTACA AAGCCCGTAT CAAGGGCACG GGCCAAATAG TAGCAATGAA ATTCATTGTC 
AAGAAAGGCA AAAACGAGAA GGAGCTGAAA AATCTGAGGA GCGAGATCGA GATTTTGACG 
AAGCTGAATC ATCCGCATAT TATCATGCTC TTTGACTCAT TTGAGACGGA TTCCGACTTT 
GTAGTGGTGA TGGAGTATGC ACAGGGTGAG CTATATGACA TCCTGGAAGA TGAAAAGCAG 
CTGCCGGCGA AGGAGGTGCA GAAGATTGCA AAGCAACTCA TCCAGGCACT GAATTACCTT 
CACTCTAATC GAATCATTCA CCGTGATATG AAGCCGCAGA ACATCTTAAT TGGACAGAAC 
GGTGCCGTAA AACTGGCAGA TTTCGGCTTT GCGCGCTCTA TGAGCTACAA CACAATCGTA 
CTAACGAGCA TCAAGGGTAC ACCGCTCTAC ATGGCTCCGG AGCTGGTGCA AGAGCGCGCG 
TACGACAACC GAGTTGACCT GTGGTCGCTA GGCTGCATAT TGTATGAATT GTACTACGGC 
AAACCGCCTT TCTACACGAA CAACCTTTTT GCTTTGATCA AGAAGATCGT TTGTGAGCCA 
GTCAAGTACG ATTCCAAGGC CAATGATCCG ATTAGCCCCG AGTTCAAGAG CTTTCTTAGC 
GGCCTCTTGA CCAAGTCTGC GTCCTCGCGG CTCAATTGGC CTGAACTGCT GAACCACCCA 
TTTGTGCAGC TGACGAAGAG TGACGCGTCG TGGCAGGATG CTATTATGCA GCACGATTCG 
AGGATGAAGG CCCGAATGGA TAGACTAGGG TGTCTTCGAC TTCATGGAAA CGCTGGTCGT 
GCGGCCCCAA AGCGCAAGTC TACCCAAAGC GATGACATTT TCAACCTGAA GACAGTGCAG 
AAGCTCACGA GCGGTTGCGA GTTCGACGTC TGCGCCACAC TCACCCAGCT GGTGCGGATG 
GCTAGGGCGT CCAATGGAGA TGTAACAAAA AGCACTGCTC TTCTTGGAGT GTTCGACTCC 
GGGGTCCTGG AGGCCGCGTT GACGCTGCTC AACGAGAAGC AGTCGGTGAA AGTTGTCGGT 
TTAGTGCTGC AGTTCGTGCA AGAGCTGGTA TTTCCGGAAC ATGGTGATTT GCTTGCCTTT 
CCCTCCCAGC GTCCGAAACG CGACGGGTTG GCGGTGTTAG AGGAAAAACA CTCACGTCAG 
CAGGAGGATC TGTTTATTCG ACAGCAGGTT GCTCTGAAGC TGATGAAGAA GCCTCACACG 
GCGCTTGATT TCATCATTAG CGAAATAAGC AGCGGCGGCG ATTCTCTTGC CGAAACGTGT 
GTGAAGATCA TGTTCCAGTG TTTCCGCTGG GAGAACAGCT TTGGGCCGAT GGTGACACAG 
CTGCGGACTT TTCCGGAAAT GTGGGCGGCC ATCCTCAAAT CTGTCAACCA TCACAGTGTC 
TCAAGGGGCG AGACGTCGCA CGAGTATGCG GCTCTTGTTT TTCACACGGT GTCTATCGTC 
ATTCCGCACG TCAAGCTGGC ATCCCCGCAG CGGATAAATC GTGAGGAGGT GCTGGAGCTC 
GTGACGCAAG GTCTCTCCGC TGTTTGCTAT TACGAGGCCG GCATGGTAGA CGCGCATCGG 
AATAAAACCC CCCCGCTGGT CTATGCAGCG GCAGCGGCAC TCCTCATCGC CTTCGCTCAT 
CGAGAGCTGA AGGATATTGT CTCGTTTAAG GTGAATGGTG CGCTGCTAGA CGGGATTTAC 
TCCATCGTCG ATGCCGTGAC AGACGCACCG AGTCGACCTG TAACGCCGCG GGCGCTGGGA 
AGTAGCTATG GGTATCCTGA CTACGGCTTG CTAGATGGCG TCGCCCATAT GCTGTCGCTG 
GTTTTCTCAG ACTCAGACTC GCTCGTCTAC GCCAAGCTGC CTGGTAGATC AGAGCACCGC 
TTTTTGGAGA GTGACACCAA AAGCCTGGCA CTGTTGGTCA TGACACTTCT GCGTGACAGC 
GATCCAAGGA TGGAATTGTC ACCCAACGGT GTCCAGACGC TGTTGCGAGC GGCGCAGCAG 
ATATTTCAGC AGGAGAAGGA GCAAGCTCTG TCGATGAGTT TGCTGATGGA GCCGATAGCC 
CCCTACTCAG GGGAGTCAGG GAGCCTATGC TGGCTCTCAG TCATCTGCCG CACAATGAAA 
ACCGATTACT TCCGTCAGCT TTTTTACTGG CCGGCGTGTC GCGGCGGTGG CGCGACCGGC 
GTCAGCGCGC ACGTGACAAT TGTGTCTCAG ATTTTATCTG ACTCACTGCG TCCCGTGAGC 
TCGTCCTCAA ATCCAACGCC TGTGGAGGAC AAGCTGCTAG GCGACGTCAG CCGCGTTCTG 
TACAAGGAGA AAGTTATCGA GCTGCTTGTG CACGCTATGG ACTACTCTGA GGGGGTTTTT 
CTCGGGAGCC CGTTCGCCAT CATCGCGAAG CTGTGCGCCA ACTCCGCAGA CTCCATCAAG 
GCCTTCGTAG ACTGTGGCGG TGTAGACGCC GCTCGAATCA GGCGTATTCT CGACCCAGAC 
AAAGCAGGCA CAGGGCTGAT GTCGGACGGA TTGGTGGTGC TTTCGCAAAT GGCACGCATG 
TCTGCAGAGT TTTATGAGCC CATTCATAGA TCCAACCTGT ATGATTGCTT GGCTGCGCTC 
CTCCAGCACT CAGAAAAAGA TTTACGCGGC AAGACATGCA CGCTTATTGG GAATTTGTGT 
AAGCACTCCG ACTTCTTCTT TGAGCCACTT GAGAAGAACC ACATTGTAGA GCGGCTGGTG 
AAGTGCTGCA GCGACAGCGA CGCACAGACA CAGAAGTTGG CAGCGTTTGC CATTGGCAAT 
GCTGCGTTTC ATAGTGGCTA TCTGTACAAT TTGCTGAGCC CAGCCATTCC CTCGCTGGTG 
GGTCTTCTGG CGTGTGGGGA CGCAAAGACG CGTCAAAACG CTGCCGGGGC GCTGAGCAAC 
TTTGTTCGAA ACGGAGACCA GCTCGTGAGC TCCTTGGCAG AGTCCAGCGT CGTTGAATCT 
CTGCTGAAGA TGTTGCGTGA CGACGACACA CCGTCATCAA AAAAGGTCGC AGTGCTCACT 
ATCAACTCGT TTTGTGCATA CGATGTATTC CGTCGCAAGT TTATTGCGCT GAACTTGCGA 
GAGGATATTC GCAAGCTGCA GCAGGACCCT AACGCGCGCG CAGACCCCTC AATTCAAAAG 
TACGTTGGCA ATCTCGTAGA TCGACTTGGT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_001464058.1
CDS	1..3273
Translation	MLVTMENYQIIESIGEGSFGKVYKARIKGTGQIVAMKFIVKKGKNEKELKNLRSEIEILTKLNHPHIIMLFDSFETDSDFVVVMEYAQGELYDILEDEKQLPAKEVQKIAKQLIQALNYLHSNRIIHRDMKPQNILIGQNGAVKLADFGFARSMSYNTIVLTSIKGTPLYMAPELVQERAYDNRVDLWSLGCILYELYYGKPPFYTNNLFALIKKIVCEPVKYDSKANDPISPEFKSFLSGLLTKSASSRLNWPELLNHPFVQLTKSDASWQDAIMQHDSRMKARMDRLGCLRLHGNAGRAAPKRKSTQSDDIFNLKTVQKLTSGCEFDVCATLTQLVRMARASNGDVTKSTALLGVFDSGVLEAALTLLNEKQSVKVVGLVLQFVQELVFPEHGDLLAFPSQRPKRDGLAVLEEKHSRQQEDLFIRQQVALKLMKKPHTALDFIISEISSGGDSLAETCVKIMFQCFRWENSFGPMVTQLRTFPEMWAAILKSVNHHSVSRGETSHEYAALVFHTVSIVIPHVKLASPQRINREEVLELVTQGLSAVCYYEAGMVDAHRNKTPPLVYAAAAALLIAFAHRELKDIVSFKVNGALLDGIYSIVDAVTDAPSRPVTPRALGSSYGYPDYGLLDGVAHMLSLVFSDSDSLVYAKLPGRSEHRFLESDTKSLALLVMTLLRDSDPRMELSPNGVQTLLRAAQQIFQQEKEQALSMSLLMEPIAPYSGESGSLCWLSVICRTMKTDYFRQLFYWPACRGGGATGVSAHVTIVSQILSDSLRPVSSSSNPTPVEDKLLGDVSRVLYKEKVIELLVHAMDYSEGVFLGSPFAIIAKLCANSADSIKAFVDCGGVDAARIRRILDPDKAGTGLMSDGLVVLSQMARMSAEFYEPIHRSNLYDCLAALLQHSEKDLRGKTCTLIGNLCKHSDFFFEPLEKNHIVERLVKCCSDSDAQTQKLAAFAIGNAAFHSGYLYNLLSPAIPSLVGLLACGDAKTRQNAAGALSNFVRNGDQLVSSLAESSVVESLLKMLRDDDTPSSKKVAVLTINSFCAYDVFRRKFIALNLREDIRKLQQDPNARADPSIQKYVGNLVDRLG

Target ORF information:

RefSeq Version	XM_001464021.1
Organism	Leishmania infantum JPCM5
Definition	Leishmania infantum JPCM5 mitogen-activated protein kinase kinase 2 (MKK2), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_001464021.1

ORF Insert Sequence:

ATGCTTGTGA CGATGGAGAA CTACCAAATA ATCGAGTCCA TCGGAGAGGG CTCCTTTGGC 
AAAGTGTACA AAGCCCGTAT CAAGGGCACG GGCCAAATAG TAGCAATGAA ATTCATTGTC 
AAGAAAGGCA AAAACGAGAA GGAGCTGAAA AATCTGAGGA GCGAGATCGA GATTTTGACG 
AAGCTGAATC ATCCGCATAT TATCATGCTC TTTGACTCAT TTGAGACGGA TTCCGACTTT 
GTAGTGGTGA TGGAGTATGC ACAGGGTGAG CTATATGACA TCCTGGAAGA TGAAAAGCAG 
CTGCCGGCGA AGGAGGTGCA GAAGATTGCA AAGCAACTCA TCCAGGCACT GAATTACCTT 
CACTCTAATC GAATCATTCA CCGTGATATG AAGCCGCAGA ACATCTTAAT TGGACAGAAC 
GGTGCCGTAA AACTGGCAGA TTTCGGCTTT GCGCGCTCTA TGAGCTACAA CACAATCGTA 
CTAACGAGCA TCAAGGGTAC ACCGCTCTAC ATGGCTCCGG AGCTGGTGCA AGAGCGCGCG 
TACGACAACC GAGTTGACCT GTGGTCGCTA GGCTGCATAT TGTATGAATT GTACTACGGC 
AAACCGCCTT TCTACACGAA CAACCTTTTT GCTTTGATCA AGAAGATCGT TTGTGAGCCA 
GTCAAGTACG ATTCCAAGGC CAATGATCCG ATTAGCCCCG AGTTCAAGAG CTTTCTTAGC 
GGCCTCTTGA CCAAGTCTGC GTCCTCGCGG CTCAATTGGC CTGAACTGCT GAACCACCCA 
TTTGTGCAGC TGACGAAGAG TGACGCGTCG TGGCAGGATG CTATTATGCA GCACGATTCG 
AGGATGAAGG CCCGAATGGA TAGACTAGGG TGTCTTCGAC TTCATGGAAA CGCTGGTCGT 
GCGGCCCCAA AGCGCAAGTC TACCCAAAGC GATGACATTT TCAACCTGAA GACAGTGCAG 
AAGCTCACGA GCGGTTGCGA GTTCGACGTC TGCGCCACAC TCACCCAGCT GGTGCGGATG 
GCTAGGGCGT CCAATGGAGA TGTAACAAAA AGCACTGCTC TTCTTGGAGT GTTCGACTCC 
GGGGTCCTGG AGGCCGCGTT GACGCTGCTC AACGAGAAGC AGTCGGTGAA AGTTGTCGGT 
TTAGTGCTGC AGTTCGTGCA AGAGCTGGTA TTTCCGGAAC ATGGTGATTT GCTTGCCTTT 
CCCTCCCAGC GTCCGAAACG CGACGGGTTG GCGGTGTTAG AGGAAAAACA CTCACGTCAG 
CAGGAGGATC TGTTTATTCG ACAGCAGGTT GCTCTGAAGC TGATGAAGAA GCCTCACACG 
GCGCTTGATT TCATCATTAG CGAAATAAGC AGCGGCGGCG ATTCTCTTGC CGAAACGTGT 
GTGAAGATCA TGTTCCAGTG TTTCCGCTGG GAGAACAGCT TTGGGCCGAT GGTGACACAG 
CTGCGGACTT TTCCGGAAAT GTGGGCGGCC ATCCTCAAAT CTGTCAACCA TCACAGTGTC 
TCAAGGGGCG AGACGTCGCA CGAGTATGCG GCTCTTGTTT TTCACACGGT GTCTATCGTC 
ATTCCGCACG TCAAGCTGGC ATCCCCGCAG CGGATAAATC GTGAGGAGGT GCTGGAGCTC 
GTGACGCAAG GTCTCTCCGC TGTTTGCTAT TACGAGGCCG GCATGGTAGA CGCGCATCGG 
AATAAAACCC CCCCGCTGGT CTATGCAGCG GCAGCGGCAC TCCTCATCGC CTTCGCTCAT 
CGAGAGCTGA AGGATATTGT CTCGTTTAAG GTGAATGGTG CGCTGCTAGA CGGGATTTAC 
TCCATCGTCG ATGCCGTGAC AGACGCACCG AGTCGACCTG TAACGCCGCG GGCGCTGGGA 
AGTAGCTATG GGTATCCTGA CTACGGCTTG CTAGATGGCG TCGCCCATAT GCTGTCGCTG 
GTTTTCTCAG ACTCAGACTC GCTCGTCTAC GCCAAGCTGC CTGGTAGATC AGAGCACCGC 
TTTTTGGAGA GTGACACCAA AAGCCTGGCA CTGTTGGTCA TGACACTTCT GCGTGACAGC 
GATCCAAGGA TGGAATTGTC ACCCAACGGT GTCCAGACGC TGTTGCGAGC GGCGCAGCAG 
ATATTTCAGC AGGAGAAGGA GCAAGCTCTG TCGATGAGTT TGCTGATGGA GCCGATAGCC 
CCCTACTCAG GGGAGTCAGG GAGCCTATGC TGGCTCTCAG TCATCTGCCG CACAATGAAA 
ACCGATTACT TCCGTCAGCT TTTTTACTGG CCGGCGTGTC GCGGCGGTGG CGCGACCGGC 
GTCAGCGCGC ACGTGACAAT TGTGTCTCAG ATTTTATCTG ACTCACTGCG TCCCGTGAGC 
TCGTCCTCAA ATCCAACGCC TGTGGAGGAC AAGCTGCTAG GCGACGTCAG CCGCGTTCTG 
TACAAGGAGA AAGTTATCGA GCTGCTTGTG CACGCTATGG ACTACTCTGA GGGGGTTTTT 
CTCGGGAGCC CGTTCGCCAT CATCGCGAAG CTGTGCGCCA ACTCCGCAGA CTCCATCAAG 
GCCTTCGTAG ACTGTGGCGG TGTAGACGCC GCTCGAATCA GGCGTATTCT CGACCCAGAC 
AAAGCAGGCA CAGGGCTGAT GTCGGACGGA TTGGTGGTGC TTTCGCAAAT GGCACGCATG 
TCTGCAGAGT TTTATGAGCC CATTCATAGA TCCAACCTGT ATGATTGCTT GGCTGCGCTC 
CTCCAGCACT CAGAAAAAGA TTTACGCGGC AAGACATGCA CGCTTATTGG GAATTTGTGT 
AAGCACTCCG ACTTCTTCTT TGAGCCACTT GAGAAGAACC ACATTGTAGA GCGGCTGGTG 
AAGTGCTGCA GCGACAGCGA CGCACAGACA CAGAAGTTGG CAGCGTTTGC CATTGGCAAT 
GCTGCGTTTC ATAGTGGCTA TCTGTACAAT TTGCTGAGCC CAGCCATTCC CTCGCTGGTG 
GGTCTTCTGG CGTGTGGGGA CGCAAAGACG CGTCAAAACG CTGCCGGGGC GCTGAGCAAC 
TTTGTTCGAA ACGGAGACCA GCTCGTGAGC TCCTTGGCAG AGTCCAGCGT CGTTGAATCT 
CTGCTGAAGA TGTTGCGTGA CGACGACACA CCGTCATCAA AAAAGGTCGC AGTGCTCACT 
ATCAACTCGT TTTGTGCATA CGATGTATTC CGTCGCAAGT TTATTGCGCT GAACTTGCGA 
GAGGATATTC GCAAGCTGCA GCAGGACCCT AACGCGCGCG CAGACCCCTC AATTCAAAAG 
TACGTTGGCA ATCTCGTAGA TCGACTTGGT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania.
Genome research21(12)2129-42(2011 Dec)
Rogers MB,Hilley JD,Dickens NJ,Wilkes J,Bates PA,Depledge DP,Harris D,Her Y,Herzyk P,Imamura H,Otto TD,Sanders M,Seeger K,Dujardin JC,Berriman M,Smith DF,Hertz-Fowler C,Mottram JC

Comparative genomic analysis of three Leishmania species that cause diverse human disease.
Nature genetics39(7)839-47(2007 Jul)
Peacock CS,Seeger K,Harris D,Murphy L,Ruiz JC,Quail MA,Peters N,Adlem E,Tivey A,Aslett M,Kerhornou A,Ivens A,Fraser A,Rajandream MA,Carver T,Norbertczak H,Chillingworth T,Hance Z,Jagels K,Moule S,Ormond D,Rutter S,Squares R,Whitehead S,Rabbinowitsch E,Arrowsmith C,White B,Thurston S,Bringaud F,Baldauf SL,Faulconbridge A,Jeffares D,Depledge DP,Oyola SO,Hilley JD,Brito LO,Tosi LR,Barrell B,Cruz AK,Mottram JC,Smith DF,Berriman M

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MKK2 cDNA ORF clone, Leishmania infantum JPCM5

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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