Gene Symbol | EDN1 |
Entrez Gene ID | 494214 |
Full Name | endothelin 1 |
Synonyms | ET-1 |
Gene Type | protein-coding |
Organism | Felis catus(Domestic cat) |
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ORF » Species Summary » Felis catus » EDN1 cDNA ORF clone
Gene Symbol | EDN1 |
Entrez Gene ID | 494214 |
Full Name | endothelin 1 |
Synonyms | ET-1 |
Gene Type | protein-coding |
Organism | Felis catus(Domestic cat) |
mRNA | Protein | Name |
---|---|---|
NM_001009386.1 | NP_001009386.1 | endothelin-1 precursor |
XM_011282148.3 | XP_011280450.1 | endothelin-1 isoform X1 |
XM_011282148.2 | XP_011280450.1 | endothelin-1 isoform X1 |
Endogenous endothelin 1 mediates angiotensin II-induced hypertrophy in electrically paced cardiac myocytes through EGFR transactivation, reactive oxygen species and NHE-1.
Correa MV, Nolly MB, Caldiz CI, de Cingolani GE, Cingolani HE, Ennis IL
Pflugers Archiv : European journal of physiology466(9)1819-30(2014 Sep)
Endothelin-1 concentrations in bronchoalveolar lavage fluid of cats with experimentally induced asthma.
Sharp CR, Lee-Fowler TM, Reinero CR
Journal of veterinary internal medicine27(4)982-4(2013 Jul-Aug)
Activation of p38 MAPK is involved in endothelin-1-stimulated COX-2 expression in cultured Feline esophageal smooth muscle cells.
Song HJ, Min YS, Shin CY, Jeong JH, Sohn UD
Molecules and cells22(1)44-50(2006 Aug)
The positive inotropic effect of angiotensin II: role of endothelin-1 and reactive oxygen species.
Cingolani HE, Villa-Abrille MC, Cornelli M, Nolly A, Ennis IL, Garciarena C, Suburo AM, Torbidoni V, Correa MV, Camiliónde Hurtado MC, Aiello EA
Hypertension (Dallas, Tex. : 1979)47(4)727-34(2006 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following EDN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EDN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFb00062 | |
Clone ID Related Accession (Same CDS sequence) | NM_001009386.1 | |
Accession Version | NM_001009386.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1514217600000 | |
Organism | Felis catus(domestic cat) | |
Product | endothelin-1 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB197698.1. ##Evidence-Data-START## Transcript exon combination :: AB197698.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02058438, SAMN02058439 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGATTATC TCCCCGTGCT TTTCTCTCTG CTGTTGGTGG TTTTCCAAGG AGCTCCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001009386.1 |
CDS | 313..921 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGATTATC TCCCCGTGCT TTTCTCTCTG CTGTTGGTGG TTTTCCAAGG AGCTCCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OFb24885 | |
Clone ID Related Accession (Same CDS sequence) | XM_011282148.3 , XM_011282148.2 | |
Accession Version | XM_011282148.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1512921600000 | |
Organism | Felis catus(domestic cat) | |
Product | endothelin-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_018727.3) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 12, 2017 this sequence version replaced XM_011282148.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Felis catus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATTATT TCCCCGTGCT TTTCTCTCTG CTGTTTGTGG TTTTCCAAGG AACTCCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011280450.1 |
CDS | 668..1273 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGATTATT TCCCCGTGCT TTTCTCTCTG CTGTTTGTGG TTTTCCAAGG AACTCCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OFb24885 | |
Clone ID Related Accession (Same CDS sequence) | XM_011282148.3 , XM_011282148.2 | |
Accession Version | XM_011282148.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 1482854400000 | |
Organism | Felis catus(Domestic cat) | |
Product | endothelin-1 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_018727.2) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 29, 2016 this sequence version replaced XM_011282148.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Felis catus Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATTATT TCCCCGTGCT TTTCTCTCTG CTGTTTGTGG TTTTCCAAGG AACTCCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011280450.1 |
CDS | 595..1200 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGATTATT TCCCCGTGCT TTTCTCTCTG CTGTTTGTGG TTTTCCAAGG AACTCCAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Endogenous endothelin 1 mediates angiotensin II-induced hypertrophy in electrically paced cardiac myocytes through EGFR transactivation, reactive oxygen species and NHE-1. |
Endothelin-1 concentrations in bronchoalveolar lavage fluid of cats with experimentally induced asthma. |
Activation of p38 MAPK is involved in endothelin-1-stimulated COX-2 expression in cultured Feline esophageal smooth muscle cells. |
The positive inotropic effect of angiotensin II: role of endothelin-1 and reactive oxygen species. |