Dana\GF12469 cDNA ORF clone, Drosophila ananassae

Gene
Clones
gRNAs

Summary

Gene Symbol	Dana\GF12469
Entrez Gene ID	6495319
Full Name	GF12469 gene product from transcript GF12469-RA
Synonyms	GF12469,dana_GLEANR_12472
Gene Type	protein-coding
Organism	Drosophila ananassae

mRNA and Protein(s)

mRNA	Protein	Name
XM_014907763.1	XP_014763249.1	uncharacterized protein, isoform B
XM_001958601.2	XP_001958637.1	uncharacterized protein, isoform A

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Assembly reconciliation.
Zimin AV, Smith DR, Sutton G, Yorke JA
Bioinformatics (Oxford, England)24(1)42-5(2008 Jan)

Evolution of genes and genomes on the Drosophila phylogeny.
, Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B, Markow TA, Kaufman TC, Kellis M, Gelbart W, Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, Abad JP, Abt DN, Adryan B, Aguade M, Akashi H, Anderson WW, Aquadro CF, Ardell DH, Arguello R, Artieri CG, Barbash DA, Barker D, Barsanti P, Batterham P, Batzoglou S, Begun D, Bhutkar A, Blanco E, Bosak SA, Bradley RK, Brand AD, Brent MR, Brooks AN, Brown RH, Butlin RK, Caggese C, Calvi BR, Bernardo de Carvalho A, Caspi A, Castrezana S, Celniker SE, Chang JL, Chapple C, Chatterji S, Chinwalla A, Civetta A, Clifton SW, Comeron JM, Costello JC, Coyne JA, Daub J, David RG, Delcher AL, Delehaunty K, Do CB, Ebling H, Edwards K, Eickbush T, Evans JD, Filipski A, Findeiss S, Freyhult E, Fulton L, Fulton R, Garcia AC, Gardiner A, Garfield DA, Garvin BE, Gibson G, Gilbert D, Gnerre S, Godfrey J, Good R, Gotea V, Gravely B, Greenberg AJ, Griffiths-Jones S, Gross S, Guigo R, Gustafson EA, Haerty W, Hahn MW, Halligan DL, Halpern AL, Halter GM, Han MV, Heger A, Hillier L, Hinrichs AS, Holmes I, Hoskins RA, Hubisz MJ, Hultmark D, Huntley MA, Jaffe DB, Jagadeeshan S, Jeck WR, Johnson J, Jones CD, Jordan WC, Karpen GH, Kataoka E, Keightley PD, Kheradpour P, Kirkness EF, Koerich LB, Kristiansen K, Kudrna D, Kulathinal RJ, Kumar S, Kwok R, Lander E, Langley CH, Lapoint R, Lazzaro BP, Lee SJ, Levesque L, Li R, Lin CF, Lin MF, Lindblad-Toh K, Llopart A, Long M, Low L, Lozovsky E, Lu J, Luo M, Machado CA, Makalowski W, Marzo M, Matsuda M, Matzkin L, McAllister B, McBride CS, McKernan B, McKernan K, Mendez-Lago M, Minx P, Mollenhauer MU, Montooth K, Mount SM, Mu X, Myers E, Negre B, Newfeld S, Nielsen R, Noor MA, O'Grady P, Pachter L, Papaceit M, Parisi MJ, Parisi M, Parts L, Pedersen JS, Pesole G, Phillippy AM, Ponting CP, Pop M, Porcelli D, Powell JR, Prohaska S, Pruitt K, Puig M, Quesneville H, Ram KR, Rand D, Rasmussen MD, Reed LK, Reenan R, Reily A, Remington KA, Rieger TT, Ritchie MG, Robin C, Rogers YH, Rohde C, Rozas J, Rubenfield MJ, Ruiz A, Russo S, Salzberg SL, Sanchez-Gracia A, Saranga DJ, Sato H, Schaeffer SW, Schatz MC, Schlenke T, Schwartz R, Segarra C, Singh RS, Sirot L, Sirota M, Sisneros NB, Smith CD, Smith TF, Spieth J, Stage DE, Stark A, Stephan W, Strausberg RL, Strempel S, Sturgill D, Sutton G, Sutton GG, Tao W, Teichmann S, Tobari YN, Tomimura Y, Tsolas JM, Valente VL, Venter E, Venter JC, Vicario S, Vieira FG, Vilella AJ, Villasante A, Walenz B, Wang J, Wasserman M, Watts T, Wilson D, Wilson RK, Wing RA, Wolfner MF, Wong A, Wong GK, Wu CI, Wu G, Yamamoto D, Yang HP, Yang SP, Yorke JA, Yoshida K, Zdobnov E, Zhang P, Zhang Y, Zimin AV, Baldwin J, Abdouelleil A, Abdulkadir J, Abebe A, Abera B, Abreu J, Acer SC, Aftuck L, Alexander A, An P, Anderson E, Anderson S, Arachi H, Azer M, Bachantsang P, Barry A, Bayul T, Berlin A, Bessette D, Bloom T, Blye J, Boguslavskiy L, Bonnet C, Boukhgalter B, Bourzgui I, Brown A, Cahill P, Channer S, Cheshatsang Y, Chuda L, Citroen M, Collymore A, Cooke P, Costello M, D'Aco K, Daza R, De Haan G, DeGray S, DeMaso C, Dhargay N, Dooley K, Dooley E, Doricent M, Dorje P, Dorjee K, Dupes A, Elong R, Falk J, Farina A, Faro S, Ferguson D, Fisher S, Foley CD, Franke A, Friedrich D, Gadbois L, Gearin G, Gearin CR, Giannoukos G, Goode T, Graham J, Grandbois E, Grewal S, Gyaltsen K, Hafez N, Hagos B, Hall J, Henson C, Hollinger A, Honan T, Huard MD, Hughes L, Hurhula B, Husby ME, Kamat A, Kanga B, Kashin S, Khazanovich D, Kisner P, Lance K, Lara M, Lee W, Lennon N, Letendre F, LeVine R, Lipovsky A, Liu X, Liu J, Liu S, Lokyitsang T, Lokyitsang Y, Lubonja R, Lui A, MacDonald P, Magnisalis V, Maru K, Matthews C, McCusker W, McDonough S, Mehta T, Meldrim J, Meneus L, Mihai O, Mihalev A, Mihova T, Mittelman R, Mlenga V, Montmayeur A, Mulrain L, Navidi A, Naylor J, Negash T, Nguyen T, Nguyen N, Nicol R, Norbu C, Norbu N, Novod N, O'Neill B, Osman S, Markiewicz E, Oyono OL, Patti C, Phunkhang P, Pierre F, Priest M, Raghuraman S, Rege F, Reyes R, Rise C, Rogov P, Ross K, Ryan E, Settipalli S, Shea T, Sherpa N, Shi L, Shih D, Sparrow T, Spaulding J, Stalker J, Stange-Thomann N, Stavropoulos S, Stone C, Strader C, Tesfaye S, Thomson T, Thoulutsang Y, Thoulutsang D, Topham K, Topping I, Tsamla T, Vassiliev H, Vo A, Wangchuk T, Wangdi T, Weiand M, Wilkinson J, Wilson A, Yadav S, Young G, Yu Q, Zembek L, Zhong D, Zimmer A, Zwirko Z, Jaffe DB, Alvarez P, Brockman W, Butler J, Chin C, Gnerre S, Grabherr M, Kleber M, Mauceli E, MacCallum I
Nature450(7167)203-18(2007 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dana\GF12469 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dana\GF12469 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODh05680	XM_001958601.2 Latest version!	Drosophila ananassae uncharacterized protein, transcript variant A (Dana\GF12469), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ODh20202	XM_014907763.1 Latest version!	Drosophila ananassae uncharacterized protein, transcript variant B (Dana\GF12469), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dana\GF12469 ( XM_001958601.2 ) cDNA ORF clone, Drosophila ananassae -> XP_001958637.1 Drosophila ananassae uncharacterized protein, transcript variant A (Dana\GF12469), mRNA.

Price & Availability↑

CloneID	ODh05680
Clone ID Related Accession (Same CDS sequence)	XM_001958601.2
Accession Version	XM_001958601.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1059bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1450108800000
Organism	Drosophila ananassae
Product	uncharacterized protein, isoform A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NW_001939294). On Dec 16, 2015 this sequence version replaced XM_001958601.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 1.04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGTGGAAAA TACATAACAA GCTCTTAATC TACATACTCT GGATTATGGA AATAAGATTA 
GTGTCCAGCT TTACATCCGC CATGCTCTGC GCCCGGATAC CGGGCCTCAC GCCGGCCCAG 
CGTCATATGT GCGGCGAGAT GCCCGACGCT CTGATCGCCC TGGGCGAGGG CCACCAGCTG 
GGCGCCCAGG AGTGCCAGCA CCAGTTCCGG GGCCACCGCT GGAACTGTTC GGAGGTGTGG 
CAGCGTAATG TCTTTGCCCA TGTTATACCC ACAGCTTCAC GTGAGGCGGC CTACACCTAT 
GCGATAGCCA GTGCCGGAGC GGCATATGCG GTGACTGCCG CCTGTGCCCG TGGCAACATC 
TCCACCTGCG GCTGCGATGT GCGGCACAAG ACCGCACCCG TAGCTGAAGG AGCACCGGAA 
GAGCCCTGGA AGTGGGGCGG TTGTTCGGCA GATGTGGATT TCGGAATGCG GTATGCGAGA 
AGATTCATGG ATGCCCGGGA ACTAGAGCGC GATTCAAGAA CGCTAATGAA TCTACACAAC 
AATCGAGCAG GGAGAACGTT GGTGAAGAAA ATGCTTCGCA CAGACTGCAA GTGCCATGGC 
GTAAGTGGAT CCTGTGTGAT GAAGACCTGC TGGAAGAGCC TGCCGCCTTT CCGGCTGATC 
GGCGACAAGC TGATGCAAAA ATATCAAAAA GCCAAAACTG TTCAAGCCGT CAAAGGCAAA 
CGTGGACTGA GATTAGTAAT AAGCAGAAAG AAGCACACTG GAGTAGCTCG TGCCCCGAAA 
CCGGTGCTCC ATTGGCCAAA GCGGATGGAA CTGATCTATC TGGAGGCGTC ACCCAATTAC 
TGTGAGCGTA GCCTGCAGGC GGGCAGCCAG GGCACCGCCG GAAGGATCTG CCAGCACGGT 
GGCCACGGCC CGCAGAGTTG CGACCTCCTA TGCTGTGGGC GTGGCCACAA CACGCAGCAC 
ATCCGGGTGA CGAAGCAGTG CCGCTGCCAG TTCCGATGGT GCTGCGAGGT GAAGTGCGAT 
GAATGCGACG AGAGCTACGA GGAGTTCACC TGTAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_001958637.1
CDS	1442..2500
Translation	MWKIHNKLLIYILWIMEIRLVSSFTSAMLCARIPGLTPAQRHMCGEMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDVRHKTAPVAEGAPEEPWKWGGCSADVDFGMRYARRFMDARELERDSRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLIGDKLMQKYQKAKTVQAVKGKRGLRLVISRKKHTGVARAPKPVLHWPKRMELIYLEASPNYCERSLQAGSQGTAGRICQHGGHGPQSCDLLCCGRGHNTQHIRVTKQCRCQFRWCCEVKCDECDESYEEFTCK

Target ORF information:

RefSeq Version	XM_001958601.2
Organism	Drosophila ananassae
Definition	Drosophila ananassae uncharacterized protein, transcript variant A (Dana\GF12469), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_001958601.2

ORF Insert Sequence:

ATGTGGAAAA TACATAACAA GCTCTTAATC TACATACTCT GGATTATGGA AATAAGATTA 
GTGTCCAGCT TTACATCCGC CATGCTCTGC GCCCGGATAC CGGGCCTCAC GCCGGCCCAG 
CGTCATATGT GCGGCGAGAT GCCCGACGCT CTGATCGCCC TGGGCGAGGG CCACCAGCTG 
GGCGCCCAGG AGTGCCAGCA CCAGTTCCGG GGCCACCGCT GGAACTGTTC GGAGGTGTGG 
CAGCGTAATG TCTTTGCCCA TGTTATACCC ACAGCTTCAC GTGAGGCGGC CTACACCTAT 
GCGATAGCCA GTGCCGGAGC GGCATATGCG GTGACTGCCG CCTGTGCCCG TGGCAACATC 
TCCACCTGCG GCTGCGATGT GCGGCACAAG ACCGCACCCG TAGCTGAAGG AGCACCGGAA 
GAGCCCTGGA AGTGGGGCGG TTGTTCGGCA GATGTGGATT TCGGAATGCG GTATGCGAGA 
AGATTCATGG ATGCCCGGGA ACTAGAGCGC GATTCAAGAA CGCTAATGAA TCTACACAAC 
AATCGAGCAG GGAGAACGTT GGTGAAGAAA ATGCTTCGCA CAGACTGCAA GTGCCATGGC 
GTAAGTGGAT CCTGTGTGAT GAAGACCTGC TGGAAGAGCC TGCCGCCTTT CCGGCTGATC 
GGCGACAAGC TGATGCAAAA ATATCAAAAA GCCAAAACTG TTCAAGCCGT CAAAGGCAAA 
CGTGGACTGA GATTAGTAAT AAGCAGAAAG AAGCACACTG GAGTAGCTCG TGCCCCGAAA 
CCGGTGCTCC ATTGGCCAAA GCGGATGGAA CTGATCTATC TGGAGGCGTC ACCCAATTAC 
TGTGAGCGTA GCCTGCAGGC GGGCAGCCAG GGCACCGCCG GAAGGATCTG CCAGCACGGT 
GGCCACGGCC CGCAGAGTTG CGACCTCCTA TGCTGTGGGC GTGGCCACAA CACGCAGCAC 
ATCCGGGTGA CGAAGCAGTG CCGCTGCCAG TTCCGATGGT GCTGCGAGGT GAAGTGCGAT 
GAATGCGACG AGAGCTACGA GGAGTTCACC TGTAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dana\GF12469 ( XM_014907763.1 ) cDNA ORF clone, Drosophila ananassae -> XP_014763249.1 Drosophila ananassae uncharacterized protein, transcript variant B (Dana\GF12469), mRNA.

Price & Availability↑

CloneID	ODh20202
Clone ID Related Accession (Same CDS sequence)	XM_014907763.1
Accession Version	XM_014907763.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	1450108800000
Organism	Drosophila ananassae
Product	uncharacterized protein, isoform B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NW_001939294). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 1.04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCTCTGCG CCCGGATACC GGGCCTCACG CCGGCCCAGC GTCATATGTG CGGCGAGATG 
CCCGACGCTC TGATCGCCCT GGGCGAGGGC CACCAGCTGG GCGCCCAGGA GTGCCAGCAC 
CAGTTCCGGG GCCACCGCTG GAACTGTTCG GAGGTGTGGC AGCGTAATGT CTTTGCCCAT 
GTTATACCCA CAGCTTCACG TGAGGCGGCC TACACCTATG CGATAGCCAG TGCCGGAGCG 
GCATATGCGG TGACTGCCGC CTGTGCCCGT GGCAACATCT CCACCTGCGG CTGCGATGTG 
CGGCACAAGA CCGCACCCGT AGCTGAAGGA GCACCGGAAG AGCCCTGGAA GTGGGGCGGT 
TGTTCGGCAG ATGTGGATTT CGGAATGCGG TATGCGAGAA GATTCATGGA TGCCCGGGAA 
CTAGAGCGCG ATTCAAGAAC GCTAATGAAT CTACACAACA ATCGAGCAGG GAGAACGTTG 
GTGAAGAAAA TGCTTCGCAC AGACTGCAAG TGCCATGGCG TAAGTGGATC CTGTGTGATG 
AAGACCTGCT GGAAGAGCCT GCCGCCTTTC CGGCTGATCG GCGACAAGCT GATGCAAAAA 
TATCAAAAAG CCAAAACTGT TCAAGCCGTC AAAGGCAAAC GTGGACTGAG ATTAGTAATA 
AGCAGAAAGA AGCACACTGG AGTAGCTCGT GCCCCGAAAC CGGTGCTCCA TTGGCCAAAG 
CGGATGGAAC TGATCTATCT GGAGGCGTCA CCCAATTACT GTGAGCGTAG CCTGCAGGCG 
GGCAGCCAGG GCACCGCCGG AAGGATCTGC CAGCACGGTG GCCACGGCCC GCAGAGTTGC 
GACCTCCTAT GCTGTGGGCG TGGCCACAAC ACGCAGCACA TCCGGGTGAC GAAGCAGTGC 
CGCTGCCAGT TCCGATGGTG CTGCGAGGTG AAGTGCGATG AATGCGACGA GAGCTACGAG 
GAGTTCACCT GTAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_014763249.1
CDS	108..1085
Translation	MLCARIPGLTPAQRHMCGEMPDALIALGEGHQLGAQECQHQFRGHRWNCSEVWQRNVFAHVIPTASREAAYTYAIASAGAAYAVTAACARGNISTCGCDVRHKTAPVAEGAPEEPWKWGGCSADVDFGMRYARRFMDARELERDSRTLMNLHNNRAGRTLVKKMLRTDCKCHGVSGSCVMKTCWKSLPPFRLIGDKLMQKYQKAKTVQAVKGKRGLRLVISRKKHTGVARAPKPVLHWPKRMELIYLEASPNYCERSLQAGSQGTAGRICQHGGHGPQSCDLLCCGRGHNTQHIRVTKQCRCQFRWCCEVKCDECDESYEEFTCK

Target ORF information:

RefSeq Version	XM_014907763.1
Organism	Drosophila ananassae
Definition	Drosophila ananassae uncharacterized protein, transcript variant B (Dana\GF12469), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_014907763.1

ORF Insert Sequence:

ATGCTCTGCG CCCGGATACC GGGCCTCACG CCGGCCCAGC GTCATATGTG CGGCGAGATG 
CCCGACGCTC TGATCGCCCT GGGCGAGGGC CACCAGCTGG GCGCCCAGGA GTGCCAGCAC 
CAGTTCCGGG GCCACCGCTG GAACTGTTCG GAGGTGTGGC AGCGTAATGT CTTTGCCCAT 
GTTATACCCA CAGCTTCACG TGAGGCGGCC TACACCTATG CGATAGCCAG TGCCGGAGCG 
GCATATGCGG TGACTGCCGC CTGTGCCCGT GGCAACATCT CCACCTGCGG CTGCGATGTG 
CGGCACAAGA CCGCACCCGT AGCTGAAGGA GCACCGGAAG AGCCCTGGAA GTGGGGCGGT 
TGTTCGGCAG ATGTGGATTT CGGAATGCGG TATGCGAGAA GATTCATGGA TGCCCGGGAA 
CTAGAGCGCG ATTCAAGAAC GCTAATGAAT CTACACAACA ATCGAGCAGG GAGAACGTTG 
GTGAAGAAAA TGCTTCGCAC AGACTGCAAG TGCCATGGCG TAAGTGGATC CTGTGTGATG 
AAGACCTGCT GGAAGAGCCT GCCGCCTTTC CGGCTGATCG GCGACAAGCT GATGCAAAAA 
TATCAAAAAG CCAAAACTGT TCAAGCCGTC AAAGGCAAAC GTGGACTGAG ATTAGTAATA 
AGCAGAAAGA AGCACACTGG AGTAGCTCGT GCCCCGAAAC CGGTGCTCCA TTGGCCAAAG 
CGGATGGAAC TGATCTATCT GGAGGCGTCA CCCAATTACT GTGAGCGTAG CCTGCAGGCG 
GGCAGCCAGG GCACCGCCGG AAGGATCTGC CAGCACGGTG GCCACGGCCC GCAGAGTTGC 
GACCTCCTAT GCTGTGGGCG TGGCCACAAC ACGCAGCACA TCCGGGTGAC GAAGCAGTGC 
CGCTGCCAGT TCCGATGGTG CTGCGAGGTG AAGTGCGATG AATGCGACGA GAGCTACGAG 
GAGTTCACCT GTAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Assembly reconciliation.
Bioinformatics (Oxford, England)24(1)42-5(2008 Jan)
Zimin AV,Smith DR,Sutton G,Yorke JA

Evolution of genes and genomes on the Drosophila phylogeny.
Nature450(7167)203-18(2007 Nov)
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