ORF » Species Summary » Apis mellifera » LOC100576359 cDNA ORF clone

LOC100576359 cDNA ORF clone, Apis mellifera(honey bee)

The following LOC100576359 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LOC100576359 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHd21924 XM_016912442.2
Latest version!		 Apis mellifera integrator complex subunit 11 (LOC100576359), mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
View Old Accession Versions >>
OHd21924 XM_016912442.1 Apis mellifera integrator complex subunit 11 (LOC100576359), mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $307.30
$439.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    LOC100576359 ( XM_016912442.1 ) cDNA ORF clone, Apis mellifera(honey bee) -> XP_016767931.1 Apis mellifera integrator complex subunit 11 (LOC100576359), mRNA.
    Price & Availability↑
    CloneID OHd21924
    Clone ID Related Accession (Same CDS sequence) XM_016912442.1 , XM_016912442.2
    Accession Version XM_016912442.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1788bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 1463932800000
    Organism Apis mellifera(honey bee)
    Product integrator complex subunit 11
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007074.3) and transcript sequence (HP575694.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Apis mellifera Annotation Release 103 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 134 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## 

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGCCAGATA TTAAAGTTAC ACCTTTAGGA GCTGGTCAAG ATGTTGGAAG AAGTTGCATT 
    CTTGTATCAA TGGGTGGAAA GAATATTATG TTAGATTGTG GCATGCATAT GGGCTTTAAT 
    GATGAAAGGA GATTTCCAGA TTTTTCATAC ATAATCCCTG AAGGTCCAGC AACTAATTAC 
    ATAGATTGTG TGATTATTTC ACACTTTCAT TTAGATCATT GTGGTGCTCT TCCATATTTT 
    ACAGAAATGG TAGGTTATAC TGGACCAATT TATATGACAC ATCCAACAAA AGCAATTGCA 
    CCAATTTTAC TTGAAGATAT GAGAAAAGTT GCAGTAGAAC GTAAAGGAGA AAGCAATTTT 
    TTTACATCAC AAATGATAAA AGACTGTATG AAAAAAGTTA TTGCTGTTAC ATTGCATCAA 
    TCTGTAATGG TTGATTCAGA ATTAGAAATA AAAGCATATT ATGCAGGACA TGTACTTGGT 
    GCTGCAATGT TCTGGATTCG TGTTGGTTCA CAATCAATTG TATATACAGG AGATTATAAT 
    ATGACACCTG ATAGACATTT AGGTGCTGCA TGGATAGATA AATGTAGACC AGATTTACTA 
    ATATCAGAAT CAACATATGC AACAACCATT AGAGATTCTA AGAGATGTAG AGAAAGAGAT 
    TTCTTAAAAA AAGTTCATGA ATGTATAGAT AGAGGTGGCA AAGTATTAAT CCCTGTATTT 
    GCTCTTGGAC GTGCACAAGA ATTATGTATA TTATTGGAAA CATATTGGGA ACGAATGAAT 
    TTAAAAGTTC CCGTGTATTT TGCTTTAGGA TTAACTGAAA AAGCTAATAA TTATTATAAA 
    ATGTTTATTA CTTGGACAAA TCAAAAAATC AAGAAAACTT TTGTACAAAG AAATATGTTT 
    GATTTTAAAC ACATAAAGCC ATTTGATAAA GCATATATTG ATAATCCTGG AGCTATGGTA 
    GTATTTGCTA CTCCAGGTAT GTTGCATGCA GGATTATCTT TACAAATTTT TAAAAAATGG 
    GCTCCAAATG AAGCAAATAT GGTTATTATG CCTGGATTTT GTGTCCAAGG CACTGTTGGA 
    CATAAAGTTT TAAATGGTTC TAGAAGAATC GAATTTGAAA ATCGACAGAT TGTAGAAGTT 
    AAAATGGCAG TAGAATATAT GTCTTTTTCT GCTCATGCAG ATGCAAAAGG TATTATGCAA 
    TTAATACAAT ATTGTGAACC AAAAAATGTT ATGCTTGTAC ATGGTGAATT TGCTAAAATG 
    GAATTTTTAA AAGAAAAAAT AAAACAAGAA TTTGGAACTA ACTGTTATAA TCCTGCAAAT 
    GGTGAAACTT GTGTTATCAC AACTATTTCC AAAGTGCCAG TAGATGCCTC TTTAGCATTA 
    TTAAAAGCTG AAGCAAAAAA ATATTCAGCT TTGCCACCAG ATCCTAAGCG AAGAAGATTA 
    CTCCATAGTG TTTTAATGTT ACGAGAAGAT GGAGTATGTC TTGTAGATGC AGATGAAGTA 
    ACAAAAGCTG CAGGAATAAC AAAACATGTA GTAAGATTTA CATCCACTGT ACAAGTAAGA 
    GATCCTGGTC CTGCACATTC AACAACTTTG AAATTATTGC AACCATTGAA AGAAAGATTA 
    TCAGGTTGGA CAGTTCAGTT AACAGATGGA TCAATATCTG TTGAATCCGT TTTAGTAAAA 
    GTAGAAGGTG ATGAAGATGA TCAAAAAAGT GTATATGTAT CATGGACAAA TCAAGATGAA 
    GATTTGGGTA GTTATATTTT AGGATTTTTA CAAACAATGT TGAATTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016767931.1
    CDS211..1998
    Translation

    Target ORF information:

    RefSeq Version XM_016912442.1
    Organism Apis mellifera(honey bee)
    Definition Apis mellifera integrator complex subunit 11 (LOC100576359), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    		 XM_016912442.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGCCAGATA TTAAAGTTAC ACCTTTAGGA GCTGGTCAAG ATGTTGGAAG AAGTTGCATT 
    CTTGTATCAA TGGGTGGAAA GAATATTATG TTAGATTGTG GCATGCATAT GGGCTTTAAT 
    GATGAAAGGA GATTTCCAGA TTTTTCATAC ATAATCCCTG AAGGTCCAGC AACTAATTAC 
    ATAGATTGTG TGATTATTTC ACACTTTCAT TTAGATCATT GTGGTGCTCT TCCATATTTT 
    ACAGAAATGG TAGGTTATAC TGGACCAATT TATATGACAC ATCCAACAAA AGCAATTGCA 
    CCAATTTTAC TTGAAGATAT GAGAAAAGTT GCAGTAGAAC GTAAAGGAGA AAGCAATTTT 
    TTTACATCAC AAATGATAAA AGACTGTATG AAAAAAGTTA TTGCTGTTAC ATTGCATCAA 
    TCTGTAATGG TTGATTCAGA ATTAGAAATA AAAGCATATT ATGCAGGACA TGTACTTGGT 
    GCTGCAATGT TCTGGATTCG TGTTGGTTCA CAATCAATTG TATATACAGG AGATTATAAT 
    ATGACACCTG ATAGACATTT AGGTGCTGCA TGGATAGATA AATGTAGACC AGATTTACTA 
    ATATCAGAAT CAACATATGC AACAACCATT AGAGATTCTA AGAGATGTAG AGAAAGAGAT 
    TTCTTAAAAA AAGTTCATGA ATGTATAGAT AGAGGTGGCA AAGTATTAAT CCCTGTATTT 
    GCTCTTGGAC GTGCACAAGA ATTATGTATA TTATTGGAAA CATATTGGGA ACGAATGAAT 
    TTAAAAGTTC CCGTGTATTT TGCTTTAGGA TTAACTGAAA AAGCTAATAA TTATTATAAA 
    ATGTTTATTA CTTGGACAAA TCAAAAAATC AAGAAAACTT TTGTACAAAG AAATATGTTT 
    GATTTTAAAC ACATAAAGCC ATTTGATAAA GCATATATTG ATAATCCTGG AGCTATGGTA 
    GTATTTGCTA CTCCAGGTAT GTTGCATGCA GGATTATCTT TACAAATTTT TAAAAAATGG 
    GCTCCAAATG AAGCAAATAT GGTTATTATG CCTGGATTTT GTGTCCAAGG CACTGTTGGA 
    CATAAAGTTT TAAATGGTTC TAGAAGAATC GAATTTGAAA ATCGACAGAT TGTAGAAGTT 
    AAAATGGCAG TAGAATATAT GTCTTTTTCT GCTCATGCAG ATGCAAAAGG TATTATGCAA 
    TTAATACAAT ATTGTGAACC AAAAAATGTT ATGCTTGTAC ATGGTGAATT TGCTAAAATG 
    GAATTTTTAA AAGAAAAAAT AAAACAAGAA TTTGGAACTA ACTGTTATAA TCCTGCAAAT 
    GGTGAAACTT GTGTTATCAC AACTATTTCC AAAGTGCCAG TAGATGCCTC TTTAGCATTA 
    TTAAAAGCTG AAGCAAAAAA ATATTCAGCT TTGCCACCAG ATCCTAAGCG AAGAAGATTA 
    CTCCATAGTG TTTTAATGTT ACGAGAAGAT GGAGTATGTC TTGTAGATGC AGATGAAGTA 
    ACAAAAGCTG CAGGAATAAC AAAACATGTA GTAAGATTTA CATCCACTGT ACAAGTAAGA 
    GATCCTGGTC CTGCACATTC AACAACTTTG AAATTATTGC AACCATTGAA AGAAAGATTA 
    TCAGGTTGGA CAGTTCAGTT AACAGATGGA TCAATATCTG TTGAATCCGT TTTAGTAAAA 
    GTAGAAGGTG ATGAAGATGA TCAAAAAAGT GTATATGTAT CATGGACAAA TCAAGATGAA 
    GATTTGGGTA GTTATATTTT AGGATTTTTA CAAACAATGT TGAATTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    LOC100576359 ( XM_016912442.2 ) cDNA ORF clone, Apis mellifera(honey bee) -> XP_016767931.1 Apis mellifera integrator complex subunit 11 (LOC100576359), mRNA.
    Price & Availability↑
    CloneID OHd21924
    Clone ID Related Accession (Same CDS sequence) XM_016912442.1 , XM_016912442.2
    Accession Version XM_016912442.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1788bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 1537200000000
    Organism Apis mellifera(honey bee)
    Product integrator complex subunit 11
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037642.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 19, 2018 this sequence version replaced XM_016912442.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Apis mellifera Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGCCAGATA TTAAAGTTAC ACCTTTAGGA GCTGGTCAAG ATGTTGGAAG AAGTTGCATT 
    CTTGTATCAA TGGGTGGAAA GAATATTATG TTAGATTGTG GCATGCATAT GGGCTTTAAT 
    GATGAAAGGA GATTTCCAGA TTTTTCATAC ATAATCCCTG AAGGTCCAGC AACTAATTAC 
    ATAGATTGTG TGATTATTTC ACACTTTCAT TTAGATCATT GTGGTGCTCT TCCATATTTT 
    ACAGAAATGG TAGGTTATAC TGGACCAATT TATATGACAC ATCCAACAAA AGCAATTGCA 
    CCAATTTTAC TTGAAGATAT GAGAAAAGTT GCAGTAGAAC GTAAAGGAGA AAGCAATTTT 
    TTTACATCAC AAATGATAAA AGACTGTATG AAAAAAGTTA TTGCTGTTAC ATTGCATCAA 
    TCTGTAATGG TTGATTCAGA ATTAGAAATA AAAGCATATT ATGCAGGACA TGTACTTGGT 
    GCTGCAATGT TCTGGATTCG TGTTGGTTCA CAATCAATTG TATATACAGG AGATTATAAT 
    ATGACACCTG ATAGACATTT AGGTGCTGCA TGGATAGATA AATGTAGACC AGATTTACTA 
    ATATCAGAAT CAACATATGC AACAACCATT AGAGATTCTA AGAGATGTAG AGAAAGAGAT 
    TTCTTAAAAA AAGTTCATGA ATGTATAGAT AGAGGTGGCA AAGTATTAAT CCCTGTATTT 
    GCTCTTGGAC GTGCACAAGA ATTATGTATA TTATTGGAAA CATATTGGGA ACGAATGAAT 
    TTAAAAGTTC CCGTGTATTT TGCTTTAGGA TTAACTGAAA AAGCTAATAA TTATTATAAA 
    ATGTTTATTA CTTGGACAAA TCAAAAAATC AAGAAAACTT TTGTACAAAG AAATATGTTT 
    GATTTTAAAC ACATAAAGCC ATTTGATAAA GCATATATTG ATAATCCTGG AGCTATGGTA 
    GTATTTGCTA CTCCAGGTAT GTTGCATGCA GGATTATCTT TACAAATTTT TAAAAAATGG 
    GCTCCAAATG AAGCAAATAT GGTTATTATG CCTGGATTTT GTGTCCAAGG CACTGTTGGA 
    CATAAAGTTT TAAATGGTTC TAGAAGAATC GAATTTGAAA ATCGACAGAT TGTAGAAGTT 
    AAAATGGCAG TAGAATATAT GTCTTTTTCT GCTCATGCAG ATGCAAAAGG TATTATGCAA 
    TTAATACAAT ATTGTGAACC AAAAAATGTT ATGCTTGTAC ATGGTGAATT TGCTAAAATG 
    GAATTTTTAA AAGAAAAAAT AAAACAAGAA TTTGGAACTA ACTGTTATAA TCCTGCAAAT 
    GGTGAAACTT GTGTTATCAC AACTATTTCC AAAGTGCCAG TAGATGCCTC TTTAGCATTA 
    TTAAAAGCTG AAGCAAAAAA ATATTCAGCT TTGCCACCAG ATCCTAAGCG AAGAAGATTA 
    CTCCATAGTG TTTTAATGTT ACGAGAAGAT GGAGTATGTC TTGTAGATGC AGATGAAGTA 
    ACAAAAGCTG CAGGAATAAC AAAACATGTA GTAAGATTTA CATCCACTGT ACAAGTAAGA 
    GATCCTGGTC CTGCACATTC AACAACTTTG AAATTATTGC AACCATTGAA AGAAAGATTA 
    TCAGGTTGGA CAGTTCAGTT AACAGATGGA TCAATATCTG TTGAATCCGT TTTAGTAAAA 
    GTAGAAGGTG ATGAAGATGA TCAAAAAAGT GTATATGTAT CATGGACAAA TCAAGATGAA 
    GATTTGGGTA GTTATATTTT AGGATTTTTA CAAACAATGT TGAATTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016767931.1
    CDS210..1997
    Translation

    Target ORF information:

    RefSeq Version XM_016912442.2
    Organism Apis mellifera(honey bee)
    Definition Apis mellifera integrator complex subunit 11 (LOC100576359), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    		 XM_016912442.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGCCAGATA TTAAAGTTAC ACCTTTAGGA GCTGGTCAAG ATGTTGGAAG AAGTTGCATT 
    CTTGTATCAA TGGGTGGAAA GAATATTATG TTAGATTGTG GCATGCATAT GGGCTTTAAT 
    GATGAAAGGA GATTTCCAGA TTTTTCATAC ATAATCCCTG AAGGTCCAGC AACTAATTAC 
    ATAGATTGTG TGATTATTTC ACACTTTCAT TTAGATCATT GTGGTGCTCT TCCATATTTT 
    ACAGAAATGG TAGGTTATAC TGGACCAATT TATATGACAC ATCCAACAAA AGCAATTGCA 
    CCAATTTTAC TTGAAGATAT GAGAAAAGTT GCAGTAGAAC GTAAAGGAGA AAGCAATTTT 
    TTTACATCAC AAATGATAAA AGACTGTATG AAAAAAGTTA TTGCTGTTAC ATTGCATCAA 
    TCTGTAATGG TTGATTCAGA ATTAGAAATA AAAGCATATT ATGCAGGACA TGTACTTGGT 
    GCTGCAATGT TCTGGATTCG TGTTGGTTCA CAATCAATTG TATATACAGG AGATTATAAT 
    ATGACACCTG ATAGACATTT AGGTGCTGCA TGGATAGATA AATGTAGACC AGATTTACTA 
    ATATCAGAAT CAACATATGC AACAACCATT AGAGATTCTA AGAGATGTAG AGAAAGAGAT 
    TTCTTAAAAA AAGTTCATGA ATGTATAGAT AGAGGTGGCA AAGTATTAAT CCCTGTATTT 
    GCTCTTGGAC GTGCACAAGA ATTATGTATA TTATTGGAAA CATATTGGGA ACGAATGAAT 
    TTAAAAGTTC CCGTGTATTT TGCTTTAGGA TTAACTGAAA AAGCTAATAA TTATTATAAA 
    ATGTTTATTA CTTGGACAAA TCAAAAAATC AAGAAAACTT TTGTACAAAG AAATATGTTT 
    GATTTTAAAC ACATAAAGCC ATTTGATAAA GCATATATTG ATAATCCTGG AGCTATGGTA 
    GTATTTGCTA CTCCAGGTAT GTTGCATGCA GGATTATCTT TACAAATTTT TAAAAAATGG 
    GCTCCAAATG AAGCAAATAT GGTTATTATG CCTGGATTTT GTGTCCAAGG CACTGTTGGA 
    CATAAAGTTT TAAATGGTTC TAGAAGAATC GAATTTGAAA ATCGACAGAT TGTAGAAGTT 
    AAAATGGCAG TAGAATATAT GTCTTTTTCT GCTCATGCAG ATGCAAAAGG TATTATGCAA 
    TTAATACAAT ATTGTGAACC AAAAAATGTT ATGCTTGTAC ATGGTGAATT TGCTAAAATG 
    GAATTTTTAA AAGAAAAAAT AAAACAAGAA TTTGGAACTA ACTGTTATAA TCCTGCAAAT 
    GGTGAAACTT GTGTTATCAC AACTATTTCC AAAGTGCCAG TAGATGCCTC TTTAGCATTA 
    TTAAAAGCTG AAGCAAAAAA ATATTCAGCT TTGCCACCAG ATCCTAAGCG AAGAAGATTA 
    CTCCATAGTG TTTTAATGTT ACGAGAAGAT GGAGTATGTC TTGTAGATGC AGATGAAGTA 
    ACAAAAGCTG CAGGAATAAC AAAACATGTA GTAAGATTTA CATCCACTGT ACAAGTAAGA 
    GATCCTGGTC CTGCACATTC AACAACTTTG AAATTATTGC AACCATTGAA AGAAAGATTA 
    TCAGGTTGGA CAGTTCAGTT AACAGATGGA TCAATATCTG TTGAATCCGT TTTAGTAAAA 
    GTAGAAGGTG ATGAAGATGA TCAAAAAAGT GTATATGTAT CATGGACAAA TCAAGATGAA 
    GATTTGGGTA GTTATATTTT AGGATTTTTA CAAACAATGT TGAATTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    Finding the missing honey bee genes: lessons learned from a genome upgrade.
    BMC genomics1586(2014 Jan)
    Elsik CG,Worley KC,Bennett AK,Beye M,Camara F,Childers CP,de Graaf DC,Debyser G,Deng J,Devreese B,Elhaik E,Evans JD,Foster LJ,Graur D,Guigo R,,Hoff KJ,Holder ME,Hudson ME,Hunt GJ,Jiang H,Joshi V,Khetani RS,Kosarev P,Kovar CL,Ma J,Maleszka R,Moritz RF,Munoz-Torres MC,Murphy TD,Muzny DM,Newsham IF,Reese JT,Robertson HM,Robinson GE,Rueppell O,Solovyev V,Stanke M,Stolle E,Tsuruda JM,Vaerenbergh MV,Waterhouse RM,Weaver DB,Whitfield CW,Wu Y,Zdobnov EM,Zhang L,Zhu D,Gibbs RA,


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