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Homo sapiens (human)

Browse by Letter Index, Genomic Locus


p53-Dependent G1/S DNA damage checkpoint Transcriptional activation of cell cycle inhibitor p21
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Mitotic Spindle Checkpoint
G1 Phase Cyclin D associated events in G1
Cyclin E associated events during G1/S transition G1/S-Specific Transcription
Inhibition of replication initiation of damaged DNA by RB1/E2F1 DNA replication initiation
CDK-mediated phosphorylation and removal of Cdc6 DNA strand elongation
Establishment of Sister Chromatid Cohesion Cyclin A/B1 associated events during G2/M transition
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes Centrosome maturation
M Phase Golgi Cisternae Pericentriolar Stack Reorganization
Condensation of Prometaphase Chromosomes Mitotic Anaphase
M/G1 Transition CDC6 association with the ORC:origin complex
Regulation of mitotic cell cycle Nuclear Events (kinase and transcription factor activation)
VEGFR2 mediated vascular permeability Signaling by ERBB2
SHC1 events in ERBB2 signaling GRB7 events in ERBB2 signaling
Downregulation of ERBB2:ERBB3 signaling RAF-independent MAPK1/3 activation
MAPK3 (ERK1) activation Rho GTPase cycle
RHO GTPases Activate Rhotekin and Rhophilins Formyl peptide receptors bind formyl peptides and many other ligands
Muscarinic acetylcholine receptors Dopamine receptors
Eicosanoid ligand-binding receptors Leukotriene receptors
Nucleotide-like (purinergic) receptors Lysosphingolipid and LPA receptors
Opsins GPCR downstream signaling
Signaling by Wnt WNT ligand biogenesis and trafficking
TCF dependent signaling in response to WNT Formation of the beta-catenin:TCF transactivating complex
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 IRS-related events triggered by IGF1R
Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Signaling by Retinoic Acid Signaling by Leptin
Ligand-receptor interactions Activation of SMO
TRAIL signaling YAP1- and WWTR1 (TAZ)-stimulated gene expression
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase II Transcription Initiation mRNA Capping
mRNA Splicing - Minor Pathway Transport of the SLBP Dependant Mature mRNA
Formation of the Editosome mRNA Editing: A to I Conversion
tRNA Aminoacylation Gene Silencing by RNA
TET1,2,3 and TDG demethylate DNA Metabolism of proteins
Translation Formation of the ternary complex, and subsequently, the 43S complex
Protein folding Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC Synthesis of dolichyl-phosphate mannose
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Synthesis of Dolichyl-phosphate
Sialic acid metabolism Transport to the Golgi and subsequent modification
ER to Golgi Anterograde Transport Mitochondrial protein import
Serotonin Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation
GABA synthesis Dopamine clearance from the synaptic cleft
Highly calcium permeable nicotinic acetylcholine receptors Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
Trafficking of GluR2-containing AMPA receptors CREB phosphorylation through the activation of CaMKII
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits HCN channels
Potassium transport channels Tandem pore domain potassium channels
TWIK-releated acid-sensitive K+ channel (TASK) Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Transcriptional activation of mitochondrial biogenesis Signaling by Ligand-Responsive EGFR Variants in Cancer
Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by FGFR2 in disease
FGFR3 mutant receptor activation t(4;14) translocations of FGFR3
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