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Homo sapiens (human) Degradation of the extracellular matrix (provided by Reactome)

112 gene

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.


Gene Symbol Full Name
COL13A1 collagen type XIII alpha 1 chain
TIMP2 TIMP metallopeptidase inhibitor 2
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18
COL26A1 collagen type XXVI alpha 1 chain
TLL1 tolloid like 1
MIR4758 microRNA 4758
CASP3 caspase 3
COL16A1 collagen type XVI alpha 1 chain
CTSD cathepsin D
CAPN11 calpain 11
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase
LAMA3 laminin subunit alpha 3
CAPN12 calpain 12
MMP11 matrix metallopeptidase 11
MMP24 matrix metallopeptidase 24
CAPN6 calpain 6
CTSL cathepsin L
CAPNS2 calpain small subunit 2
KLK2 kallikrein related peptidase 2
HTRA1 HtrA serine peptidase 1
CAPNS1 calpain small subunit 1
COL14A1 collagen type XIV alpha 1 chain
CTSS cathepsin S
MMP16 matrix metallopeptidase 16
MMP20 matrix metallopeptidase 20
COL17A1 collagen type XVII alpha 1 chain
CAPN3 calpain 3
LAMC1 laminin subunit gamma 1
KLK7 kallikrein related peptidase 7
CAPN9 calpain 9
TMPRSS6 transmembrane serine protease 6
MMP1 matrix metallopeptidase 1
CAPN15 calpain 15
CDH1 cadherin 1
CTSB cathepsin B
PRSS1 serine protease 1
ADAM8 ADAM metallopeptidase domain 8
NCSTN nicastrin
DCN decorin
ELANE elastase, neutrophil expressed
LAMB1 laminin subunit beta 1
MMP7 matrix metallopeptidase 7
COL18A1 collagen type XVIII alpha 1 chain
COL23A1 collagen type XXIII alpha 1 chain
BSG basigin (Ok blood group)
MMP8 matrix metallopeptidase 8
FURIN furin, paired basic amino acid cleaving enzyme
COL9A3 collagen type IX alpha 3 chain
CAPN2 calpain 2
COL12A1 collagen type XII alpha 1 chain
CTSK cathepsin K
KLKB1 kallikrein B1
CAPN10 calpain 10
CAPN7 calpain 7
CAST calpastatin
PRSS2 serine protease 2
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1
MMP12 matrix metallopeptidase 12
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif 16
ACAN aggrecan
LAMB3 laminin subunit beta 3
A2M alpha-2-macroglobulin
ADAM17 ADAM metallopeptidase domain 17
BMP1 bone morphogenetic protein 1
BCAN brevican
ADAM9 ADAM metallopeptidase domain 9
PSEN1 presenilin 1
MMP14 matrix metallopeptidase 14
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4
MIR4260 microRNA 4260
MIR936 microRNA 936
MMP3 matrix metallopeptidase 3
SPOCK3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3
MMP19 matrix metallopeptidase 19
LAMA5 laminin subunit alpha 5
OPTC opticin
TPSAB1 tryptase alpha/beta 1
TLL2 tolloid like 2
CAPN8 calpain 8
CD44 CD44 molecule (Indian blood group)
NID1 nidogen 1
CTSG cathepsin G
ADAM15 ADAM metallopeptidase domain 15
CAPN5 calpain 5
MMP25 matrix metallopeptidase 25
CAPN1 calpain 1
CAPN13 calpain 13
MMP13 matrix metallopeptidase 13
CTRB2 chymotrypsinogen B2
CTRB1 chymotrypsinogen B1
CAPN14 calpain 14
COL19A1 collagen type XIX alpha 1 chain
MMP9 matrix metallopeptidase 9
LAMC2 laminin subunit gamma 2
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8
TIMP1 TIMP metallopeptidase inhibitor 1
SPP1 secreted phosphoprotein 1
MMP10 matrix metallopeptidase 10
HSPG2 heparan sulfate proteoglycan 2
CMA1 chymase 1
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ORF