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Homo sapiens (human) Insulin receptor signalling cascade (provided by Reactome)

Browse by Letter Index, Genomic Locus

299 gene

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.


Gene Symbol Full Name
PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3
FGF18 fibroblast growth factor 18
PSMA7 proteasome subunit alpha 7
PSPN persephin
SPTAN1 spectrin alpha, non-erythrocytic 1
FGFR3 fibroblast growth factor receptor 3
PPP2R1B protein phosphatase 2 scaffold subunit Abeta
HGF hepatocyte growth factor
UBB ubiquitin B
CAMK2A calcium/calmodulin dependent protein kinase II alpha
VCL vinculin
SPTBN1 spectrin beta, non-erythrocytic 1
HBEGF heparin binding EGF like growth factor
CAB39L calcium binding protein 39 like
FGB fibrinogen beta chain
IL2 interleukin 2
IL2RG interleukin 2 receptor subunit gamma
KLB klotho beta
ARRB2 arrestin beta 2
WDR83 WD repeat domain 83
EREG epiregulin
CAB39 calcium binding protein 39
PPP2R5A protein phosphatase 2 regulatory subunit B'alpha
FGF17 fibroblast growth factor 17
PSMD14 proteasome 26S subunit, non-ATPase 14
NRG1 neuregulin 1
PDGFRA platelet derived growth factor receptor alpha
NRG4 neuregulin 4
RASGRP1 RAS guanyl releasing protein 1
PPP2R1A protein phosphatase 2 scaffold subunit Aalpha
DUSP6 dual specificity phosphatase 6
PSMD5 proteasome 26S subunit, non-ATPase 5
PSMB5 proteasome subunit beta 5
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
RASA4 RAS p21 protein activator 4
DUSP16 dual specificity phosphatase 16
FGFR2 fibroblast growth factor receptor 2
PSMD3 proteasome 26S subunit, non-ATPase 3
MAPK3 mitogen-activated protein kinase 3
FN1 fibronectin 1
GRIN2B glutamate ionotropic receptor NMDA type subunit 2B
SPTBN5 spectrin beta, non-erythrocytic 5
PPP5C protein phosphatase 5 catalytic subunit
RASGRP3 RAS guanyl releasing protein 3
PPP2R5E protein phosphatase 2 regulatory subunit B'epsilon
PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1
RRAGB Ras related GTP binding B
EGFR epidermal growth factor receptor
CAMK2B calcium/calmodulin dependent protein kinase II beta
RRAGD Ras related GTP binding D
BRAF B-Raf proto-oncogene, serine/threonine kinase
SPTB spectrin beta, erythrocytic
PSMB4 proteasome subunit beta 4
DUSP4 dual specificity phosphatase 4
PSMB11 proteasome subunit beta 11
PPP2R5D protein phosphatase 2 regulatory subunit B'delta
PSMA3 proteasome subunit alpha 3
PSMB9 proteasome subunit beta 9
DUSP5 dual specificity phosphatase 5
MIR7703 microRNA 7703
JAK2 Janus kinase 2
PAQR3 progestin and adipoQ receptor family member 3
PSMA1 proteasome subunit alpha 1
RRAGA Ras related GTP binding A
NRAS NRAS proto-oncogene, GTPase
GRB2 growth factor receptor bound protein 2
IRS2 insulin receptor substrate 2
RASA1 RAS p21 protein activator 1
FGG fibrinogen gamma chain
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1
STRADB STE20-related kinase adaptor beta
TSC2 TSC complex subunit 2
BRAP BRCA1 associated protein
AKAP9 A-kinase anchoring protein 9
PSMB7 proteasome subunit beta 7
ANGPT1 angiopoietin 1
FGF8 fibroblast growth factor 8
FGF7 fibroblast growth factor 7
JAK3 Janus kinase 3
SPRED3 sprouty related EVH1 domain containing 3
SHC3 SHC adaptor protein 3
RPS6KB1 ribosomal protein S6 kinase B1
LAT linker for activation of T cells
PRKAB1 protein kinase AMP-activated non-catalytic subunit beta 1
FGFR1 fibroblast growth factor receptor 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
SPTBN4 spectrin beta, non-erythrocytic 4
NRG3 neuregulin 3
FGF16 fibroblast growth factor 16
INS insulin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
TLN1 talin 1
PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2
SPRED1 sprouty related EVH1 domain containing 1
RASGEF1A RasGEF domain family member 1A
PIK3R4 phosphoinositide-3-kinase regulatory subunit 4
STRADA STE20-related kinase adaptor alpha
PSMA6 proteasome subunit alpha 6
MAP2K2 mitogen-activated protein kinase kinase 2
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