ORF » Species Summary » Homo sapiens » Reactome » Negative regulation of the PI3K/AKT network

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Homo sapiens (human) Negative regulation of the PI3K/AKT network (provided by Reactome)

Browse by Letter Index, Genomic Locus

94 gene

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.


Gene Symbol Full Name
EGF epidermal growth factor
ICOS inducible T cell costimulator
PPP2CB protein phosphatase 2 catalytic subunit beta
SRC SRC proto-oncogene, non-receptor tyrosine kinase
KIT KIT proto-oncogene receptor tyrosine kinase
FGF20 fibroblast growth factor 20
FGFR4 fibroblast growth factor receptor 4
FGF23 fibroblast growth factor 23
TRAT1 T cell receptor associated transmembrane adaptor 1
CD86 CD86 molecule
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
FGF22 fibroblast growth factor 22
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
CD19 CD19 molecule
PDGFRB platelet derived growth factor receptor beta
PIK3R1 phosphoinositide-3-kinase regulatory subunit 1
FGF5 fibroblast growth factor 5
FGF1 fibroblast growth factor 1
AKT2 AKT serine/threonine kinase 2
FGF9 fibroblast growth factor 9
PIK3R2 phosphoinositide-3-kinase regulatory subunit 2
FGF4 fibroblast growth factor 4
FGF3 fibroblast growth factor 3
AKT3 AKT serine/threonine kinase 3
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
FGF2 fibroblast growth factor 2
PPP2R5C protein phosphatase 2 regulatory subunit B'gamma
VAV1 vav guanine nucleotide exchange factor 1
MET MET proto-oncogene, receptor tyrosine kinase
PPP2R5B protein phosphatase 2 regulatory subunit B'beta
PDGFA platelet derived growth factor subunit A
LCK LCK proto-oncogene, Src family tyrosine kinase
THEM4 thioesterase superfamily member 4
INSR insulin receptor
MAPK1 mitogen-activated protein kinase 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
PPP2CA protein phosphatase 2 catalytic subunit alpha
KL klotho
KITLG KIT ligand
FGF19 fibroblast growth factor 19
AKT1 AKT serine/threonine kinase 1
NRG2 neuregulin 2
BTC betacellulin
TRIB3 tribbles pseudokinase 3
FGF6 fibroblast growth factor 6
PIK3R3 phosphoinositide-3-kinase regulatory subunit 3
ERBB2 erb-b2 receptor tyrosine kinase 2
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
FRS2 fibroblast growth factor receptor substrate 2
IRS1 insulin receptor substrate 1
ERBB4 erb-b2 receptor tyrosine kinase 4
GAB1 GRB2 associated binding protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
ERBB3 erb-b2 receptor tyrosine kinase 3
FYN FYN proto-oncogene, Src family tyrosine kinase
FGF10 fibroblast growth factor 10
PDGFB platelet derived growth factor subunit B
FGF18 fibroblast growth factor 18
FGFR3 fibroblast growth factor receptor 3
PPP2R1B protein phosphatase 2 scaffold subunit Abeta
HGF hepatocyte growth factor
HBEGF heparin binding EGF like growth factor
KLB klotho beta
EREG epiregulin
PPP2R5A protein phosphatase 2 regulatory subunit B'alpha
FGF17 fibroblast growth factor 17
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma
IER3 immediate early response 3
NRG1 neuregulin 1
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta
PDGFRA platelet derived growth factor receptor alpha
CD28 CD28 molecule
NRG4 neuregulin 4
PPP2R1A protein phosphatase 2 scaffold subunit Aalpha
PTEN phosphatase and tensin homolog
FGFR2 fibroblast growth factor receptor 2
MAPK3 mitogen-activated protein kinase 3
PPP2R5E protein phosphatase 2 regulatory subunit B'epsilon
EGFR epidermal growth factor receptor
PPP2R5D protein phosphatase 2 regulatory subunit B'delta
GRB2 growth factor receptor bound protein 2
IRS2 insulin receptor substrate 2
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase type 2 beta
FGF8 fibroblast growth factor 8
FGF7 fibroblast growth factor 7
FGFR1 fibroblast growth factor receptor 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
NRG3 neuregulin 3
FGF16 fibroblast growth factor 16
CD80 CD80 molecule
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
INS insulin
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
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