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Xenopus tropicalis (tropical clawed frog)


Sialic acid metabolism Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
Reactions specific to the hybrid N-glycan synthesis pathway SUMO is proteolytically processed
Insulin processing ATF6 (ATF6-alpha) activates chaperones
Protein repair Apoptosis
Ligand-independent caspase activation via DCC Activation, myristolyation of BID and translocation to mitochondria
Formation of apoptosome SMAC-mediated dissociation of IAP:caspase complexes
Apoptotic execution phase Regulated Necrosis
Regulation of necroptotic cell death CASP8 activity is inhibited
Cell Cycle Stabilization of p53
Autodegradation of the E3 ubiquitin ligase COP1 Cyclin A:Cdk2-associated events at S phase entry
Synthesis of DNA DNA replication initiation
DNA strand elongation Polymerase switching
Association of licensing factors with the pre-replicative complex Loss of Nlp from mitotic centrosomes
AURKA Activation by TPX2 M Phase
Mitotic Prophase MASTL Facilitates Mitotic Progression
Clearance of Nuclear Envelope Membranes from Chromatin Initiation of Nuclear Envelope Reformation
Assembly of the pre-replicative complex APC/C-mediated degradation of cell cycle proteins
Phosphorylation of Emi1 Extension of Telomeres
Striated Muscle Contraction Transmission across Electrical Synapses
Neurotransmitter Release Cycle Degradation of GABA
Enzymatic degradation of dopamine by COMT Enzymatic degradation of Dopamine by monoamine oxidase
Astrocytic Glutamate-Glutamine Uptake And Metabolism Highly calcium permeable nicotinic acetylcholine receptors
Activation of AMPA receptors CREB phosphorylation through the activation of CaMKII
Presynaptic function of Kainate receptors Activation of GABAB receptors
GABA A (rho) receptor activation HCN channels
Activation of G protein gated Potassium channels Potassium transport channels
Classical Kir channels Mitochondrial ABC transporters
SLC-mediated transmembrane transport Bicarbonate transporters
Sodium/Calcium exchangers Type II Na+/Pi cotransporters
Glucose transport Rhesus glycoproteins mediate ammonium transport.
Vasopressin regulates renal water homeostasis via Aquaporins Transport of glycerol from adipocytes to the liver by Aquaporins
Signaling by EGFR GAB1 signalosome
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Signaling by FGFR
FGFRL1 modulation of FGFR1 signaling FRS-mediated FGFR1 signaling
Spry regulation of FGF signaling FGFR2 ligand binding and activation
Negative regulation of FGFR2 signaling FGFR3c ligand binding and activation
FGFR4 ligand binding and activation SHC-mediated cascade:FGFR4
PI-3K cascade:FGFR4 Insulin receptor signalling cascade
PI3K Cascade NGF processing
NFG and proNGF binds to p75NTR Axonal growth inhibition (RHOA activation)
Regulated proteolysis of p75NTR Activation of TRKA receptors
TRKA activation by NGF Signalling to ERKs
Signalling to RAS Signalling to p38 via RIT and RIN
Frs2-mediated activation Signalling to ERK5
CREB phosphorylation Signaling by PDGF
Downstream signal transduction VEGFR2 mediated vascular permeability
Signaling by ERBB2 RAF-independent MAPK1/3 activation
RHO GTPases activate CIT RHO GTPases regulate CFTR trafficking
RHO GTPases Activate WASPs and WAVEs Downregulation of TGF-beta receptor signaling
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Pre-NOTCH Expression and Processing
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