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Drosophila melanogaster (fruit fly)

Browse by Letter Index, Genomic Locus


TCR signaling Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Antigen Presentation: Folding, assembly and peptide loading of class I MHC Toll Like Receptor 10 (TLR10) Cascade
MyD88 cascade initiated on plasma membrane TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Toll Like Receptor 9 (TLR9) Cascade Toll Like Receptor TLR6:TLR2 Cascade
NOD1/2 Signaling Pathway The NLRP3 inflammasome
ZBP1(DAI) mediated induction of type I IFNs Regulation of IFNG signaling
Interleukin-1 processing Interleukin-3, 5 and GM-CSF signaling
Interleukin-6 family signaling TNFR2 non-canonical NF-kB pathway
HSF1-dependent transactivation Attenuation phase
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RNA Polymerase I Transcription Initiation
RNA Polymerase III Transcription Mitochondrial transcription initiation
RNA Polymerase II Transcription Initiation RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Termination Transport of Mature mRNA derived from an Intron-Containing Transcript
Processing of Capped Intronless Pre-mRNA Mitochondrial tRNA aminoacylation
Deadenylation-dependent mRNA decay Deadenylation of mRNA
Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
KSRP (KHSRP) binds and destabilizes mRNA rRNA processing
Displacement of DNA glycosylase by APEX1 PCNA-Dependent Long Patch Base Excision Repair
HDR through MMEJ (alt-NHEJ) DNA Damage Recognition in GG-NER
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Fanconi Anemia Pathway
G2/M Checkpoints G0 and Early G1
G1/S Transition Cyclin E associated events during G1/S transition
Mitotic G2-G2/M phases Regulation of PLK1 Activity at G2/M Transition
Mitotic Prophase Nuclear Pore Complex (NPC) Disassembly
APC/C-mediated degradation of cell cycle proteins Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Cdc20:Phospho-APC/C mediated degradation of Cyclin A Chromosome Maintenance
Telomere Maintenance Hexose transport
Regulation of Glucokinase by Glucokinase Regulatory Protein Fructose metabolism
Glycosaminoglycan metabolism HS-GAG biosynthesis
Chondroitin sulfate biosynthesis Synthesis of IP3 and IP4 in the cytosol
Synthesis of IPs in the nucleus Synthesis of pyrophosphates in the cytosol
Lipid digestion, mobilization, and transport Chylomicron-mediated lipid transport
LDL-mediated lipid transport Triglyceride Biosynthesis
mitochondrial fatty acid beta-oxidation of saturated fatty acids Beta oxidation of butanoyl-CoA to acetyl-CoA
Beta-oxidation of pristanoyl-CoA Androgen biosynthesis
Phospholipid metabolism Synthesis of PE
Choline catabolism Acyl chain remodelling of PS
Acyl chain remodeling of CL Synthesis of PIPs at the ER membrane
Synthesis of PIPs at the early endosome membrane Acetylcholine regulates insulin secretion
Insulin effects increased synthesis of Xylulose-5-Phosphate AMPK inhibits chREBP transcriptional activation activity
Metabolism of nitric oxide NOSTRIN mediated eNOS trafficking
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation Regulation of pyruvate dehydrogenase (PDH) complex
Purine metabolism Pyrimidine salvage reactions
Phosphate bond hydrolysis by NUDT proteins Vitamin D (calciferol) metabolism
Amino acid synthesis and interconversion (transamination) Histidine catabolism
Phenylalanine and tyrosine catabolism Proline catabolism
Amine-derived hormones Thyroxine biosynthesis
Glyoxylate metabolism and glycine degradation Degradation of cysteine and homocysteine
Endogenous sterols Miscellaneous substrates
PAOs oxidise polyamines to amines Electron transport from NADPH to Ferredoxin
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