Company News » GenCRISPR™ NLS-wtSpCas9, his-tag

RC00001

This newly wtSpCas9 is produced by expression in an E. coli strain carrying a plasmid encoding the Cas9 gene from Streptococcus pyogenes with an nuclear localization signal (NLS) and his-tag.
RC00001
$150.00

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Description

CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and Cas9.
Note

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.