RET gene (Adenomatous Polyposis Coli)
Do you need RET gene to express the RET protein for functional or characterization studies? Get the RET gene in an expression-ready vector for your molecular biology studies by ordering a RET ORF clone.
About the RET gene
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
Genomic context of RET gene
The human RET gene is shown in the context of the human genome below. To see information about the RET gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse RET, rat RET, and human RET, as well as on-demand RET ORF clones in 183 other species.
Genomic sequence of RET gene
GenEZ™ ORF cDNA clones
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