RHO GTPase Effectors
Homo sapiens (human) RHO GTPase Effectors (provided by Reactome)
About the RHO GTPase Effectors pathway
RHO GTPases regulate cell behaviour by activating a number of downstream effectors that regulate cytoskeletal organization, intracellular trafficking and transcription (reviewed by Sahai and Marshall 2002)
The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.
286 gene
| Gene Symbol | Full Name |
|---|---|
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| ACTB | actin, beta |
| ACTG1 | actin gamma 1 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| KLK3 | kallikrein-related peptidase 3 |
| AR | androgen receptor |
| RHOA | ras homolog family member A |
| RHOB | ras homolog family member B |
| RHOC | ras homolog family member C |
| RHOG | ras homolog family member G |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| FMNL1 | formin-like 1 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CDC20 | cell division cycle 20 |
| CDC25C | cell division cycle 25C |
| CDC42 | cell division cycle 42 |
| CDH1 | cadherin 1, type 1 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CENPA | centromere protein A |
| CENPC | centromere protein C |
| CENPE | centromere protein E, 312kDa |
| CENPF | centromere protein F, 350/400kDa |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYBB | cytochrome b-245, beta polypeptide |
| DIAPH1 | diaphanous-related formin 1 |
| DIAPH2 | diaphanous-related formin 2 |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DVL1 | dishevelled segment polarity protein 1 |
| DVL2 | dishevelled segment polarity protein 2 |
| DVL3 | dishevelled segment polarity protein 3 |
| CTTN | cortactin |
| FLNA | filamin A, alpha |
| CENPI | centromere protein I |
| SFN | stratifin |
| GRB2 | growth factor receptor-bound protein 2 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2AD | histone cluster 1, H2ad |
| H2AFX | H2A histone family, member X |
| H2AFZ | H2A histone family, member Z |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BB | histone cluster 1, H2bb |
| H3F3A | H3 histone, family 3A |
| H3F3B | H3 histone, family 3B (H3.3B) |
| NCKAP1L | NCK-associated protein 1-like |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KIF2A | kinesin heavy chain member 2A |
| KIF5A | kinesin family member 5A |
| KIF5B | kinesin family member 5B |
| KLK2 | kallikrein-related peptidase 2 |
| KLC1 | kinesin light chain 1 |
| KTN1 | kinectin 1 (kinesin receptor) |
| LIMK1 | LIM domain kinase 1 |
| LIMK2 | LIM domain kinase 2 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MEN1 | multiple endocrine neoplasia I |
| MYH9 | myosin, heavy chain 9, non-muscle |
| MYH10 | myosin, heavy chain 10, non-muscle |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| MYLK | myosin light chain kinase |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| NCF2 | neutrophil cytosolic factor 2 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NCK1 | NCK adaptor protein 1 |
| NF2 | neurofibromin 2 (merlin) |
| NUP98 | nucleoporin 98kDa |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 |
| PFN1 | profilin 1 |
| PFN2 | profilin 2 |
| PLK1 | polo-like kinase 1 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
| PKN1 | protein kinase N1 |
| PKN2 | protein kinase N2 |
| MAPK1 | mitogen-activated protein kinase 1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| PTK2 | protein tyrosine kinase 2 |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
