NBN gene (nibrin)
Do you need NBN gene to express the NBN protein for functional or characterization studies? Get the NBN gene in an expression-ready vector for your molecular biology studies by ordering a NBN ORF clone.
About the NBN gene
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Genomic context of NBN gene
The human NBN gene is shown in the context of the human genome below. To see information about the NBN gene in other species, please use the Search tool to select your desired species. GenScript has in-stock ORF clones for mouse NBN, rat NBN, and human NBN, as well as on-demand NBN ORF clones in 183 other species.
Genomic sequence of NBN gene
GenEZ™ ORF cDNA clones
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